3 results match your criteria: "Federal Scientific and Clinical Center of Pediatric Hematology[Affiliation]"

Article Synopsis
  • * Results showed that younger children (under 1.5 years) had much better survival rates (91% overall survival) compared to older children (61% overall survival), with high-risk factors like stage 4 and N-myc amplification leading to poorer outcomes.
  • * Notably, treatment with anti-GD2 antibodies significantly improved survival rates in high-risk patients, indicating the need for better cancer registration to enhance understanding and treatment of neuroblastoma across Europe.
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In modern neuro-oncology and onco-hematology, intraventricular injection of chemotherapeutic agents (most typically, methotrexate) is an inevitable part of many protocols for treating patients with malignant tumors of the CNS, neuroleukemia, CNS lymphomas and some other disorders. A ventricular catheter system (also known as the Ommaya reservoir) is used to provide repeated injection of chemotherapeutic agents to cerebral ventricles. The use of modern neuronavigation systems allows one to place Ommaya reservoir in patients with narrow and slit-like ventricles.

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Malignant rhabdoid tumor of the liver presented with initial tumor rupture.

Cancer Genet

September 2014

Department of Clinical Oncology, Federal Scientific and Clinical Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russian Federation.

Malignant rhabdoid tumor (MRT) of the liver is a rare, highly aggressive tumor of early childhood. We report a 6-month-old boy who was diagnosed with MRT of the liver and presented with spontaneous tumor rupture. The patient underwent intensified chemotherapy and a radical surgical procedure.

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