Hyperbaric oxygen therapy prevents epithelial atrophy in distal tubules and TGF-β1 overexpression in diabetic rat kidneys.

Diabetic nephropathy (DN) is one of the most relevant and prevalent microvascular complications associated with Diabetes Mellitus. In recent years, hyperbaric oxygen therapy (HBO) has been used to mitigate tissue damage caused by hypoxia, thereby attenuating inflammatory processes. This study aimed to explore morphological aspects associated with DN in rats subjected to HBO.

Transmissible venereal tumour with encephalic metastasis in dogs.

From January 2000 to December 2023 the Laboratory of Animal Pathology of the Federal University of Campina Grande received 6,218 canine autopsy and biopsy submissions, with six (0.09%) autopsy cases diagnosed as transmissible venereal tumour (TVT) with encephalic metastases. The mean age of affected dogs (four females and two males) was 7 years.

Disperse Red 1 azo dye: Consequences of low-dose/low-concentration exposures in mice and zebrafish.

Color Index Disperse Red 1 (DR1), an azo dye widely used in the textile industry and released into aquatic environments, is genotoxic in somatic cells, but little is known concerning its effects on the reproductive system or the early stages of embryonic development. We have assessed the effects on the spermatozoa of male mice following oral exposure to the dye, at low doses, for 14 days. Measured endpoints were DNA damage (comet assay), miRNA-34c levels, and sperm number, morphology, and motility.

Molecular Diagnosis of the Main Hemoparasites of Dairy Cows in the State of Ceará.

Background/objectives: Trypanosomiasis and bovine babesiosis correspond to important diseases that cause great economic losses, but there are still no studies evaluating their occurrence in herds of dairy cattle in Ceará. The aim of this study was to perform molecular diagnosis of the main hemoparasites of dairy cows in the microregion of the central hinterland of Ceará.

Methods: For the molecular diagnosis of parasites, genomic material was extracted and polymerase chain reaction directed to the cdCatL-like gene for and SS rRNA of and was performed.

Storage Potential of Cactus Mucilage Powder for Incorporation into Foods and Production of Biopolymeric Films.

The objective was to investigate the physicochemical stability of stored cactus pear mucilage and assess the technological feasibility to produce polymeric films. Mucilage of cactus pear species (L.) Salm-Dyck MIU and (Haw.

Nephroprotective effects of hyperbaric oxygen therapy in murine models of acute kidney injury: A systematic review and meta-analysis.

Aims: Acute kidney injury (AKI) is a life-threatening condition marked by sudden kidney function loss and azotemia. While its management is limited to supportive care, the effects of hyperbaric oxygen therapy (HBO) on AKI remain a subject of conflicting animal research. This study aimed to systematically review and meta-analyze HBO's effects on renal function biomarkers serum creatinine (SCr) and blood urea nitrogen (BUN) in murine AKI models, also exploring tissue-level nephroprotection.

Time of Application of Desiccant Herbicides Affects Photosynthetic Pigments, Physiological Indicators, and the Quality of Cowpea Seeds.

Chemical desiccation is widely used in agriculture to anticipate harvest and mitigate the effects of adverse environmental conditions. It is applied to both grains and seeds. Although this practice is widely used, there are still significant gaps in understanding the effects of different herbicide application times on seed quality and plant physiological responses.

Effects of Kinesio tape on vascularity, pliability and height of the hypertrophic scar in burns patients: a randomized pilot clinical trial.

Deep burns damage the reticular dermis and may lead to the formation of hypertrophic scars. Compression therapy reduces local vascularity and realigns collagen fibers, resulting in esthetic and functional improvements. This study evaluated the effect of Kinesio tape compression with maximum mechanical tension on vascularity, pliability and the height of hypertrophic scars following deep burns.

Global seroprevalence and factors associated with seropositivity for feline immunodeficiency virus (FIV) in cats: A systematic review and meta-analysis.

The feline immunodeficiency virus (FIV) is a retrovirus of the Lentivirus genus, distributed worldwide, that causes persistent infection with a significant impact on the cats' health. Due to the importance of this infection in feline medicine, this pioneering study aimed to obtain an integrated estimate of the global seroprevalence of FIV in cats and to characterize the factors associated with this infection. Four electronic databases were screened for observational studies with FIV seroprevalence in cats published globally for this systematic review and meta-analysis.

Comparative assessment of growth curves in Brazilian white Morada Nova hair sheep breed.

The Morada Nova sheep breed is essential for the economy of the semi-arid region of Northeast Brazil, standing out for its adaptability, resistance to parasites and reproductive ability. However, the white variant is endangered, highlighting the importance of studies on its productivity to support conservation efforts. This study focuses on the growth curve of the Morada Nova sheep breed, using nonlinear models and analyzing flock profiles.

Effect of coconut processing by-product graded feeding on carcass traits and meat quality of lambs.

The inclusion of by-product coconut mesocarp skins (CMS) in diets was evaluated in feedlot lambs. The objective of this study was to evaluate CMS levels effects on carcass traits and meat quality of lambs. Thirty-five male lambs with an initial body weight of 16.

Chitosan Coating with Rosemary Extract Increases Shelf Life and Reduces Water Losses from Beef.

This study aimed to evaluate the influence of films based on chitosan and rosemary extract on the physicochemical, microbiological, and oxidative characteristics of beef. Refrigerated steaks of were distributed in a factorial arrangement (4 × 4) into four treatments consisting of four edible films (control; chitosan; chitosan + 4% rosemary extract; and chitosan + 8% rosemary extract) and four days of aging (0, 2, 4, and 8 days). Incorporating 4% or 8% rosemary extract into the chitosan film improved the characteristics of the films in terms of moisture absorption and elasticity.

Vermicompost and millicompost as a resource in sustainable agriculture in semiarid: decomposition, nutrient release, and microstructure under the action of nitrogen and organic-mineral fertilizers.

With the expansion of organic agriculture, research is needed to indicate economically and ecologically viable fertilizer options, especially in semiarid regions, with low soil organic matter and nitrogen content. In the Brazilian semiarid region, vermicomposts are widely used by farmers and are scientifically investigated; however, there is no information for millicompost, a new type of organic compound that has shown very promising results in other regions. Thus, this study aimed to analyze the decomposition rate, nutrient release, and microstructure evaluation of vermicomposts from different sources and of millicompost produced from plant residues, with the application of mineral nitrogen-urea and organo-mineral fertilizer in the Brazilian semiarid region.

Tofacitinib and peficitinib inhibitors of Janus kinase for autoimmune disease treatment: a quantum biochemistry approach.

Autoimmune inflammatory diseases, such as rheumatoid arthritis (RA) and ulcerative colitis, are associated with an uncontrolled production of cytokines leading to the pronounced inflammatory response of these disorders. Their therapy is currently focused on the inhibition of cytokine receptors, such as the Janus kinase (JAK) protein family. Tofacitinib and peficitinib are JAK inhibitors that have been recently approved to treat rheumatoid arthritis.

Assessment of the adaptive capacity of Morada Nova ewes with different coat coloration.

Coat color is a factor affecting heat tolerance in tropical ruminant and a particular coat color can determine which is more resilient to environmental changes. The aim of this study was to measure the level of adaptation of Morada Nova sheep with different coat color by using an Adaptability Index (AI). Adult ewes were used, including two different coat colors of Morada Nova sheep (red and white) with mean of body weight of 28.

Development of an Optical Sensor Using a Molecularly Imprinted Polymer as a Selective Extracting Agent for the Direct Quantification of Tartrazine in Real Water Samples.

This study presents a new optical sensor for tartrazine (TAR) quantification developed using a molecularly imprinted polymer (MIP) as the recognition element, with optical fiber serving as the supporting substrate. The fiber surface was functionalized with 3-(trimethoxysilyl)propyl methacrylate (MPS), and the fiber was coated with MIP using the precipitation polymerization method. The analysis of MIP immobilization on the functionalized optical fiber (FF) was conducted through the use of scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) techniques.

Modulation of Drought-Induced Stress in Cowpea Genotypes Using Exogenous Salicylic Acid.

Plant endogenous mechanisms are not always sufficient enough to mitigate drought stress, therefore, the exogenous application of elicitors, such as salicylic acid, is necessary. In this study, we assessed the mitigating action of salicylic acid (SA) in cowpea genotypes under drought conditions. An experiment was conducted with two cowpea genotypes and six treatments of drought stress and salicylic acid (T1 = Control, T2 = drought stress (stress), T3 = stress + 0.

Electrochemical Analysis of Curcumin in Real Samples Using Intelligent Materials.

Curcumin is a compound of great importance in the food industry due to its biological and pharmacological properties, which include being an antioxidant, anti-inflammatory, antibacterial, antiviral, and anticarcinogenic. This paper proposes the synthesis of an electrochemical sensor based on molecularly imprinted polymers (MIPs) and MWCNT by drop casting deposited on a glassy carbon electrode (GCE) for the selective quantification of curcumin in food samples. The synthesized compounds are characterized by Fourier transform infrared (IR), Brunauer-Emmett-Teller (BET), and electrochemical techniques such as cyclic voltammetry (CV) and differential pulse voltammetry (DPV).

The Practical Application of Bio-Inspired PMA for the Detection of Partial Discharges in High Voltage Equipment.

In this paper, the practical application of a bio-inspired antenna for partial discharge (PD) detection in high voltage equipment was evaluated in order to validate the efficiency of using this technology for PD monitoring purposes. For this, PD measurements using the bio-inspired antenna were performed on operational 69 kV potential transformers (PT) in a real substation. After the field experiment, laboratory measurements using the IEC 60270 standard method and a bio-inspired antenna were performed, simultaneously, over the evaluated PT.

Effects of cactus pear clone harvest seasons and times on the physicochemical and technological properties of resulting mucilage and biopolymeric films.

Cactus pear cladodes, clones 'Miúda' (MIU) and 'Orelha de Elefante Mexicana' (OEM) were harvested at 6 am and 8 pm during the rainy-dry, dry and rainy seasons to evaluate the effect of type of clone and harvest seasons on the physicochemical and technological properties of mucilage as well as the optical, physicochemical, mechanical, thermal and microstructural characteristics of the films obtained. The mucilage of the OEM clone presented a higher content of phenolic compounds, compared to the Nopalea genus, regardless of the season and time of harvest. Furthermore, the dry period resulted in higher carbohydrate levels, regardless of the harvest time.

Physiological Responses of Minimally Processed Sweet Potatoes Grown with Increasing Doses of Phosphate Fertilizer.

The present work aimed to study oxidative damage and protection, phenylpropanoid metabolism, and the quality of minimally processed colored sweet potatoes cultivated with increments in PO fertilization. Sweet potato was cultivated with 0, 60, 120, 180, and 240 kg ha of PO. The roots were harvested, and the P content in the roots and leaves was quantified.