1 results match your criteria: "Federal Research Center for Original and Prospective Biomedical and Pharmaceutical Technologies[Affiliation]"
Challenges in Humoral Immune Response to Adeno-Associated Viruses Determination.
Int J Mol Sci
January 2025
Federal Research Center for Original and Prospective Biomedical and Pharmaceutical Technologies, 8 Baltiyskaya Street, Moscow 125315, Russia.
Adeno-associated viruses (AAVs) are non-pathogenic, replication-deficient viruses that have gained widespread attention for their application as gene therapy vectors. While these vectors offer high transduction efficiency and long-term gene expression, the host immune response poses a significant challenge to their clinical success. This review focuses on the obstacles to evaluating the humoral response to AAVs.
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