1 results match your criteria: "Federal Research Center for Biotechnology of the Russian Academy of Sciences[Affiliation]"
Visualizing the Nucleome Using the CRISPR-Cas9 System: From in vitro to in vivo.
Biochemistry (Mosc)
January 2023
Bach Institute of Biochemistry, Federal Research Center for Biotechnology of the Russian Academy of Sciences, Moscow, 119071, Russia.
One of the latest methods in modern molecular biology is labeling genomic loci in living cells using fluorescently labeled Cas protein. The NIH Foundation has made the mapping of the 4D nucleome (the three-dimensional nucleome on a timescale) a priority in the studies aimed to improve our understanding of chromatin organization. Fluorescent methods based on CRISPR-Cas are a significant step forward in visualization of genomic loci in living cells.
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