Specific Features of the Proteomic Response of Thermophilic Bacterium to Terahertz Irradiation.

Studying the effects of terahertz (THz) radiation on the proteome of temperature-sensitive organisms is limited by a number of significant technical difficulties, one of which is maintaining an optimal temperature range to avoid thermal shock as much as possible. In the case of extremophilic species with an increased temperature tolerance, it is easier to isolate the effects of THz radiation directly. We studied the proteomic response to terahertz radiation of the thermophilic , persisting under wide temperature fluctuations with a 60 °C optimum.

Effects of a in the Hippocampus on Behavior, the Serotonin System, and BDNF.

The serotonin 5-HT receptor is one of the most abundant and widely distributed brain serotonin (5-HT) receptors that play a major role in the modulation of emotions and behavior. The 5-HT receptor gene () is under the control of transcription factor Freud-1 (also known as ). Here, using adeno-associated virus (AAV) constructs in vivo, we investigated effects of a in the hippocampus of C57BL/6J mice on behavior, the brain 5-HT system, and brain-derived neurotrophic factor (BDNF).