14 results match your criteria: "Federal Medical Centre Owo[Affiliation]"

Background: Data on the presentation, management, and outcomes of Lassa fever (LF) in children are limited.

Methods: Description of the clinical and biological features, treatment, and outcomes of reverse transcriptase and polymerase chain reaction (RT-PCR)-confirmed LF in children aged under 15, enrolled in the LASsa fever clinical COurse and Prognostic factors in an Epidemic context (LASCOPE) prospective cohort study in Nigeria between April 2018 and February 2023.

Results: One hundred twenty-four children (aged under 12 months: 19; over 12 months: 105) were hospitalized with RT-PCR-confirmed LF.

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Background: Despite the huge burden of sickle cell disease (SCD) among Nigerian children, the burden and outcome of respiratory illnesses remain undocumented. Thus, we aimed to describe the spectrum and outcome of respiratory illnesses among SCD childrenand adolescentadmissions in ten Nigerian tertiary hospitals.

Method: A retrospective review of the SCD admission records of children and adolescents with a confirmed diagnosis of respiratory illnesses from 2012 to 2021 in ten tertiary health facilities across five geopolitical zones in Nigeria was conducted.

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Myocardial infarction (MI) is usually discussed in light of some occlusion to the coronary circulation. It usually occurs in the setting of well-established risk factors such as hypertension, obesity, coronary atherosclerosis, smoking, and male gender. However, a subset of this population does not follow the clinical presentation seen in traditional MI.

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Article Synopsis
  • The study investigates the immune responses in Lassa fever (LF) survivors and their contacts in Nigeria to understand natural protection and inform vaccine development.
  • It finds that while both groups show similar T cell and antibody responses, neutralizing antibodies are predominantly present in LF survivors and provide cross-reactivity against various LASV strains.
  • The research also highlights that immune responses diminish over time, suggesting potential vaccine targets in specific areas of the LASV Glycoprotein and Nucleoprotein for future clinical trials.
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Impact of COVID-19 on global burn care.

Burns

September 2022

Division of Plastic and Reconstructive Surgery, Department of Surgery, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA.

Background: Worldwide, different strategies have been chosen to face the COVID-19-patient surge, often affecting access to health care for other patients. This observational study aimed to investigate whether the standard of burn care changed globally during the pandemic, and whether country´s income, geographical location, COVID-19-transmission pattern, and levels of specialization of the burn units affected reallocation of resources and access to burn care.

Methods: The Burn Care Survey is a questionnaire developed to collect information on the capacity to provide burn care by burn units around the world, before and during the pandemic.

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Lassa fever outcomes and prognostic factors in Nigeria (LASCOPE): a prospective cohort study.

Lancet Glob Health

April 2021

Inserm 1219, University of Bordeaux, and French National Research Institute for Sustainable Development, Bordeaux, France; Department of Infectious Diseases and Tropical Medicine, Division of Tropical Medicine and Clinical International Health, University Hospital Centre of Bordeaux, Hôpital Pellegrin, Bordeaux, France; Programme PAC-CI/ANRS Research Site, University Hospital Centre of Treichville, Abidjan, Côte d'Ivoire.

Background: Lassa fever is a viral haemorrhagic fever endemic in parts of west Africa. New treatments are needed to decrease mortality, but pretrial reference data on the disease characteristics are scarce. We aimed to document baseline characteristics and outcomes for patients hospitalised with Lassa fever in Nigeria.

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Introduction: it has been close to four years since the authors highlighted the total neglect of the oral health of street children in the Journal of Public Health Policy. Since then, the authorities appear to have simply turned the blind eye making this follow-up imperative. This follow-up report specifically examines the resultant oral health disparity between Nigeria's street children and Private, fee-paying secondary school students in Northern Nigeria.

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Background: Chronic obstructive pulmonary disease (COPD) is a complex multisystemic disorder of public health interest. It has both pulmonary and extrapulmonary manifestation that affect the Health-related Quality of Life (HRQOL) of the patients. The COPD Assessment Test (CAT) is an example of HRQOL, a self-administered questionnaire.

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Background: Laparoscopic surgery is a relatively new and expanding field of surgical therapy in Ondo state. This is a multi-centre study cataloguing the work of the authors in Ondo State, Nigeria.

Aim: To determine the indications, operative findings, and interventions at Laparoscopy in our resource challenged settings.

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Lassa fever clinical course and setting a standard of care for future randomized trials: A protocol for a cohort study of Lassa-infected patients in Nigeria (LASCOPE).

Travel Med Infect Dis

August 2021

Inserm U1219, University of Bordeaux, 146 Rue Léo Saignat, 33076, Bordeaux, France; Department of Infectious Diseases and Tropical Medicine, Division of Tropical Medicine and Clinical International Health, CHU de Bordeaux, Hôpital Pellegrin, Place Amélie Raba Léon, 33076, Bordeaux, France; Programme PAC-CI/ANRS Research Site, CHU de Treichville, 18 BP 1954 Abidjan 18, Abidjan, Côte d'Ivoire. Electronic address:

Background: Lassa Fever (LF), is a severe viral disease prevalent in Western Africa. It is classified as a priority disease by the World Health Organization (WHO). Ribavirin is the recommended therapy despite weak evidence of its efficacy.

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Delayed-onset paraparesis in Lassa fever: A case report.

Int J Infect Dis

March 2020

Lassa fever response team, Infection Control and Research Centre, Federal Medical Centre Owo, Michael Adekun Ajasin Road, PMB 1053, Owo, Ondo State, Nigeria. Electronic address:

Lassa fever (LF) is an endemic viral hemorrhagic fever in West Africa. Among the serious complications of the disease are neurological manifestations whose spectrum is incompletely known. Here we report the case of a 61-year-old man who developed a delayed-onset paraparesis a few weeks after getting infected with Lassa virus, thereby suggesting a possible association between LF and spinal cord disorders.

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An audit of 954 family planning clinic attendees, who received counselling from 2006 to 2010, was conducted at the only federal government owned tertiary hospital in Ondo state, Nigeria. Of these, 637 (66.8%) accepted a family planning method: 47.

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Objective: To assess the knowledge and attitude of rural Nigerian women to the incorporation of HIV screening as part of the routine antenatal screening test at booking.

Methods: 1 820 women were interviewed using a close ended questionnaire at the antenatal clinic of the Federal Medical Centre (FMC) Owo, Nigeria over a period of 12 months.

Results: Though the majority of the women were of low socio-economic status (85.

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We studied prospectively the effect of antenatal care on the obstetric performance of teenagers seen at a university teaching hospital over a 14-month period. When the obstetric complications among the teenagers were compared to their older counterpart, there were significantly higher complication rates, especially anaemia, preterm delivery, low birth weight and neonatal admission. After controlling for utilisation of antenatal care, significant differences were observed only in the incidence of low birth weight babies.

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