3 results match your criteria: "Federal Institute for Vaccines and Biomedicine[Affiliation]"
Viral sepsis - pathophysiology and disease manifestation.
Infection
February 2025
Paul-Ehrlich-Institute, Federal Institute for Vaccines and Biomedicine, Langen, Germany.
Viral infection is found in approximately 30% of all sepsis cases and may be followed by bacterial infection in organs such as the lungs. Sepsis manifests as fever, hemorrhagic lesions and cell death. Organ dysfunction caused by sepsis, such as meningitis and encephalitis, can lead to organ damage.
View Article and Find Full Text PDFAntibiotic Resistance and Mobile Genetic Elements in Extensively Drug-Resistant Sequence Type 147 Recovered from Germany.
Antibiotics (Basel)
October 2020
Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, 50935 Cologne, Germany.
Mobile genetic elements (MGEs), especially multidrug-resistance plasmids, are major vehicles for the dissemination of antimicrobial resistance determinants. Herein, we analyse the MGEs in three extensively drug-resistant (XDR) isolates from Germany. Whole genome sequencing (WGS) is performed using Illumina and MinION platforms followed by core-genome multi-locus sequence typing (MLST).
View Article and Find Full Text PDFMobile Genetic Elements Harboring Antibiotic Resistance Determinants in Isolates From Bolivia.
Front Microbiol
May 2020
Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany.
Article Synopsis
- Researchers used short and long DNA sequencing to study antibiotic resistance genes in multi-drug resistant bacteria from Bolivia, finding three distinct clonal lineages.
- The study identified various mobile genetic elements (MGEs), including transposons, plasmids, and resistance islands, which are essential for the bacteria’s ability to resist multiple antibiotics, especially carbapenems.
- This research highlights the complex nature of antimicrobial resistance in Bolivia, revealing the genetic mechanisms behind it and underscoring the need for further investigation and action against antibiotic resistance globally.