Application of the T1w/T2w mapping technique for spinal cord assessment in patients with degenerative cervical myelopathy.

Study Design: Retrospective case-control study.

Objectives: To investigate signal changes on T1w/T2w signal intensity ratio maps within cervical cord in patients with degenerative cervical myelopathy (DCM).

Setting: Novosibirsk Neurosurgery Center, Russia.

Brainstem and subcortical regions volume loss in patients with degenerative cervical myelopathy and its association with spinal cord compression severity.

Background: In recent years, structural and functional reorganization of the brain and changes in brainstem structural connectivity have been shown in patients with degenerative cervical myelopathy (DCM). We hypothesized that volume loss in the basal ganglia, thalami, and brainstem structures exists and is associated with spinal cord compression severity in patients with DCM.

Methods: Forty-seven patients with DCM and 25 patients with cervical radiculopathy were evaluated using cervical spinal cord and brain magnetic resonance imaging (MRI).

White and Gray Matter Perfusion in Children with Moyamoya Angiopathy after Revascularization Surgery.

Introduction: Surgical revascularization is very effective in patients with moyamoya angiopathy (MMA) and leads to improvements in cortical perfusion parameters. However, changes in white matter hemodynamics are still underestimated. To date, only a few studies have examined brain perfusion changes within deep white matter after bypass surgery in patients with MMA.

T1w/T2w ratio is associated with the brush sign and perfusion delay in watershed regions in patients with moyamoya angiopathy.

Background: It has been shown recently using the T1w/T2w mapping technique that white matter microstructural integrity impairments exist in watershed regions patients with moyamoya angiopathy (MMA). We hypothesized that these changes could be associated with the prominence of other neuroimaging markers of chronic brain ischemia, such as perfusion delay and the brush sign.

Methods: Thirteen adult patients with MMA (24 affected hemispheres) were evaluated using brain MRI and CT perfusion.

Neuroimaging in Moyamoya angiopathy: Updated review.

Moyamoya angiopathy (MMA) is a rare condition characterized by steno-occlusion of terminal portions of the internal carotid arteries and/or their proximal branches with the formation of collateral vessels network (moyamoya vessels). These changes result in chronic ischemia of the brain parenchyma with subsequent serious cerebrovascular accidents. The prognosis of MMA could be dramatically improved if the diagnosis and assessment are prompt and accurate.

'Moderate global aphasia': A generalized decline of language processing caused by glioma surgery but not stroke.

Unlike stroke, neurosurgical removal of left-hemisphere gliomas acts upon a reorganized language network and involves brain areas rarely damaged by stroke. We addressed whether this causes the profiles of neurosurgery- and stroke-induced language impairments to be distinct. K-means clustering of language assessment data (neurosurgery cohort: N = 88, stroke cohort: N = 95) identified similar profiles in both cohorts.