The potential of large language model chatbots for application to epilepsy: Let's talk about physical exercise.

In this paper, we discuss how artificial intelligence chatbots based on large-scale language models (LLMs) can be used to disseminate information about the benefits of physical exercise for individuals with epilepsy. LLMs have demonstrated the ability to generate increasingly detailed text and allow structured dialogs. These can be useful tools, providing guidance and advice to people with epilepsy on different forms of treatment as well as physical exercise.

Virtual Obstacle Avoidance Strategy: Navigating through a Complex Environment While Interacting with Virtual and Physical Elements.

Robotic walking devices can be used for intensive exercises to enhance gait rehabilitation therapies. Mixed Reality (MR) techniques may improve engagement through immersive and interactive environments. This article introduces an MR-based multimodal human-robot interaction strategy designed to enable shared control with a Smart Walker.

Effects of a 12-week training program in outdoor gym equipment in morphological and functional parameters, quality of life, and physical activity levels in older adults.

Introduction: This study aimed to investigate the effectiveness of a supervised physical training program with controlled cadence on functional fitness parameters, quality of life perception, and physical activity level in older adults.

Methods: Sixty physically independent older adults were randomly divided into three groups: Supervised Training (ST,  = 20), Unsupervised Training (UT,  = 20), and a Control Group (C,  = 20). The ST and UT groups participated in a 12-week program, performing exercises three times a week for 30 min.

Biomass-Derived Cellulose Acetate Membranes Modified with TiO/Graphene Oxide for Oil-In-Water Emulsion Treatment.

Considering the environmental impact and health risks caused by oily wastewater in the petrochemical industry, it is crucial to develop more efficient separation techniques than traditional methods, such as membrane separation, for treating stable emulsions enriched with natural surfactants. This study investigated the preparation of dense cellulose acetate membranes from a low-cost biomass precursor () and their modification with graphene oxide (GO) and TiO nanoparticles, aiming to obtain a polymeric nanocomposite with good flux characteristics and selectivity for the treatment of oil/water emulsions. The materials obtained were characterized using techniques such as X-ray diffraction, nuclear magnetic resonance spectroscopy, infrared absorption spectroscopy, along with optical and scanning electron microscopy, among others.

Effects of osteopathic manipulative treatment associated with transcranial direct current stimulation in individuals with chronic low back pain: A double-blind, randomised placebo-controlled trial.

Objective: To evaluate the effectiveness of osteopathic manipulative treatment (OMT) associated with transcranial direct current stimulation (tDCS) in reducing pain, disability, and improving quality of life in participants with non-specific chronic low back pain.

Design: A randomised double-blind clinical trial.

Setting: Clinical outpatient unit.

Capsinoids Increase Antioxidative Enzyme Activity and Prevent Obesity-Induced Cardiac Injury without Positively Modulating Body Fat Accumulation and Cardiac Oxidative Biomarkers.

Background/objectives: Capsinoids are potential antioxidant agents capable of reducing oxidative damage and the resulting complications triggered by obesity. Thus, this study aimed to investigate the effects of capsinoids on adiposity and biomarkers of cardiac oxidative stress in obese rats induced by a high-fat diet.

Methods: Male rats were exposed to a high-fat diet for 27 consecutive weeks.

Electroencephalography Neurofeedback Training with Focus on the State of Attention: An Investigation Using Source Localization and Effective Connectivity.

Identifying brain activity and flow direction can help in monitoring the effectiveness of neurofeedback tasks that aim to treat cognitive deficits. The goal of this study was to compare the neuronal electrical activity of the cortex between individuals from two groups-low and high difficulty-based on a spatial analysis of electroencephalography (EEG) acquired through neurofeedback sessions. These sessions require the subjects to maintain their state of attention when executing a task.

CORE-VTRCC Cruise Report: Geophysical Acquisition and Seafloor Sampling along the Vitória-Trindade Ridge.

This work reports the data obtained by the multidisciplinary cruise CORE-VTRCC surveying on the region around the Vitória-Trindade Ridge (VTR) aboard the vessel NHo Cruzeiro do Sul (October 18 to November 6, 2021). The main objectives of the VTRCC Cruise were (1) to assess the role of the VTR as an oceanographic barrier for bottom currents along the Brazilian margin; and (2) to characterize the morphology of the volcanic seamounts and its relationships with the carbonate sediments that cover it. For that, we performed multibeam bathymetry, magnetometry, high-resolution multichannel seismic survey, subbottom profiling survey, and seafloor sampling along the VTR and along the Columbia Deepwater Channel.

Correlating COVID-19 severity with biomarker profiles and patient prognosis.

COVID-19's long-lasting and complex impacts have become a global concern, with diverse clinical outcomes. This study evaluated 226 participants to understand the clinical spectrum of COVID-19/Long COVID (LC), exploring how disease severity correlates with sociodemographic factors and biomarkers. Determinants related to COVID-19 severity included age (P < 0.

Trends in Mortality Due to Stroke in South America between 1990 and 2019.

Stroke is the second leading cause of death and disability in Latin America; however, few epidemiological studies have been conducted in South America. An observational study was conducted to analyze trends in stroke mortality in South American (SA) countries. Age-standardized mortality rates and proportional mortality due to stroke in the populations of SA countries between 1990 and 2019 were assessed by extracting data from the Global Burden of Disease 2019 study.

Validation of Autism Stigma Knowledge - Questionnaire (ASK-Q) for Brazilian Portuguese.

Background: Low levels of knowledge among health professionals about autism spectrum disorders (ASD) can impair the care provided to people with autism. In Brazil, there are still no validated instruments that assess the knowledge of pharmacy students and pharmacists regarding ASD.

Objective: This study aimed to carry out the cross-cultural adaptation of the Autism Stigma Knowledge Questionnaire (ASK-Q) into Brazilian Portuguese and to evaluate the evidence of content validity.

Climate change impacts on dengue transmission areas in Espírito Santo state, Brazil.

Espírito Santo state, in Brazil, is a dengue-endemic region predicted to suffer from an increase in temperature and drought due to climate change, which could affect the areas with active dengue virus transmission. The study objective was modeling climatic factors and climate change effects in zones suitable for dengue virus transmission in Espírito Santo state, Brazil. Data on dengue reports from 2022 were used to determine climatic variables related to spatial distribution.

Analysis of Gait Kinematics in Smart Walker-Assisted Locomotion in Immersive Virtual Reality Scenario.

The decline in neuromusculoskeletal capabilities of older adults can affect motor control, independence, and locomotion. Because the elderly population is increasing worldwide, assisting independent mobility and improving rehabilitation therapies has become a priority. The combination of rehabilitation robotic devices and virtual reality (VR) tools can be used in gait training to improve clinical outcomes, motivation, and treatment adherence.