10 results match your criteria: "Fatima Memorial Medical and Dental College[Affiliation]"

Article Synopsis
  • Type 1 diabetes (T1D) is an autoimmune disease that destroys insulin-producing cells in the pancreas, and this study investigates its genetic links, particularly in the Pakistani population, focusing on specific genes like PTPN22, INS, NLRP3, and ICAM-1.
  • The study involved 100 T1D patients and 100 healthy controls, analyzing various genetic polymorphisms through Sanger sequencing to uncover their potential connections to T1D susceptibility.
  • Results revealed that several specific genetic variants, such as those in PTPN22 and NLRP3, showed strong associations with T1D in the Pakistani children studied, highlighting important genetic factors that contribute to the disease in this population.*
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Article Synopsis
  • Leishmania is widespread, affecting almost half the globe, and its diagnosis remains particularly difficult in low- to middle-income countries.
  • On average, it takes 4.5 years from the onset of symptoms to get a diagnosis, indicating significant delays.
  • While traditional microscopic detection methods often miss diagnoses, polymerase chain reaction (PCR) is highly effective; however, the varying clinical presentations complicate matters, especially in areas where the disease is not common.
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Enzymes are biologically active complex protein molecules that catalyze most chemical reactions in living organisms, and their inhibitors accelerate biological processes. This review emphasizes medicinal food plants and their isolated chemicals inhibiting clinically important enzymes in common diseases. A mechanistic overview was investigated to explain the mechanism of these food bases enzyme inhibitors.

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Bacterial infections are among the major complications of many viral respiratory tract illnesses, such as influenza and coronavirus disease-2019 (COVID-19). These bacterial co-infections are associated with an increase in morbidity and mortality rates. The current observational study was conducted at a tertiary care hospital in Lahore, Pakistan among COVID-19 patients with the status of oxygen dependency to see the prevalence of bacterial co-infections and their antibiotic susceptibility patterns.

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Introduction: South Asia has had a dynamic response to the ongoing COVID-19 pandemic. The overall burden and response have remained comparable across highly-burdened countries within the South Asian Region.

Methodology: Using a population-based observational design, all eight South Asian countries were analyzed using a step-wise approach.

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Method comparison of Particle Enhanced Immunoturbidimetry (PEIT) with High Performance Liquid Chromatography (HPLC) for glycated hemoglobin (HbA1c) analysis.

Clin Diabetes Endocrinol

June 2021

Department of Pathology, Dr. Shamsi and Ansari Diagnostics Laboratory, Karachi, 74800, Pakistan.

Background And Objective: High Performance Liquid Chromatography (HPLC) technique is considered as a gold standard for HbA1c analysis however all laboratories cannot adopt it due to certain limitations. Our aim was to compare Particle Enhanced Immunoturbidimetry (PEIT) method with High Performance Liquid Chromatography (HPLC) for HbA1c analysis.

Method: All blood samples were analyzed by HPLC assay on a Bio-Rad D-10 analyzer and PEIT on an Erba XL-200 analyzer.

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Approximately one half of patients develop ascites within 10 years of diagnosis of compensated cirrhosis. It is a poor prognostic indicator, with only 50% surviving beyond two years. Mortality worsens significantly to 20% to 50% at one year if the ascites becomes refractory to medical therapy.

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Prevalence of tobacco use in urban and rural areas of Pakistan; a sub-study from second National Diabetes Survey of Pakistan (NDSP) 2016 - 2017.

Pak J Med Sci

January 2020

Asher Fawwad, PhD. Professor & Head of the Biochemistry Department (BMU), Honorary Research Director (BIDE), Baqai Institute of Diabetology and Endocrinology (BIDE), Baqai Medical University (BMU), Karachi, Sindh, Pakistan.

Objective: To assess age standardized prevalence of tobacco use in urban and rural areas of Pakistan.

Methods: This is a sub-study of second National Diabetes Survey of Pakistan (NDSP) 2016-2017. Prevalence of tobacco, ex-tobacco and non-tobacco users was determined in urban/rural areas of four provinces (Punjab, Sindh, Khyber Pakhtunkhwa, and Baluchistan) of Pakistan amongst people aged greater than or equal to 20 years.

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This article was migrated. The article was marked as recommended. In medical education, Outcome-based Education (OBE) is facing many challenges due to the rapid proliferation in biomedical sciences; technology-enhanced learning; globalization of health system, and the availability of various pedagogical techniques.

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