473 results match your criteria: "Farhat Hached hospital[Affiliation]"

Injury Profiling in Male Police Cadets During Initial Training Phase: A Retrospective Cohort Study.

Am J Mens Health

December 2024

Higher Institute of Sport and Physical Education, ISSEP Ksar Saïd, Manouba University, Manouba, Tunisia.

Musculoskeletal injuries during the "Initial Training Phase" (ITP) are a major medical problem faced by law enforcement agencies worldwide. Aiming to develop an injury prevention strategy, we examined the incidence, type, associated factors, and severity of injuries and secondarily tracked their evolution over time by batches in a police academy. A retrospective cohort study was conducted using prospectively collected injury data on 979 newly recruited male police cadets enrolled in eight batches between 2015 and 2023.

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Routine pulmonary lung function tests: Interpretative strategies and challenges.

Chron Respir Dis

December 2024

Farhat HACHED Hospital, Laboratory of Physiology and Functional Explorations, University of Sousse, Sousse, Tunisia.

The diagnosis and management of common chronic respiratory diseases depend on various parameters obtained from pulmonary function tests (PFTs), such as spirometry, plethysmography, and carbon monoxide diffusion capacity (DLCO). These tests are interpreted following guidelines established by reputable scientific societies like the European Respiratory Society and the American Thoracic Society (ERS/ATS). This review aimed to offer a comprehensive framework for interpreting PFTs, incorporating the latest ERS/ATS update (i.

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Article Synopsis
  • OEIS complex is a rare birth defect involving omphalocele, bladder exstrophy, anal imperforation, and spina bifida, likely caused by multiple factors.
  • A case is reported involving a 29-year-old woman pregnant with dizygotic twins, where the condition was suspected at 22 weeks through ultrasound and confirmed with MRI.
  • The study highlights the importance of prenatal imaging in diagnosing OEIS complex for better counseling and management options before and after birth.
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Respiratory Chain Complex I Deficiency in Leber Hereditary Optic Neuropathy: Insights from Ophthalmologic and Molecular Investigations in Tunisia.

BMC Genomics

November 2024

Research Laboratory of Human Genome and Multifactorial Diseases, Faculty of Pharmacy, University of Monastir, Street Avicenne, Monastir, 5000, Tunisia.

Background: Leber hereditary optic neuropathy (LHON) is a mitochondrial DNA (mtDNA) rare disease due to the pathogenic variant of the NADH dehydrogenase enzyme. LHON is characterized by a sudden central vision loss due to focal degeneration of the retinal ganglion cell layer and optic nerve. Symptoms usually appear between the age of 18 and 35 years.

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Introduction: Chronic Obstructive Pulmonary Disease (COPD) is a respiratory condition strongly related to oxidative stress. Recent studies have explored the potential benefits of nutritional supplementation in managing several conditions.

Aim: To investigate the effects of zinc-enriched Spirulina Supplementation (ZSS) on patients with COPD.

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Discrimination, Heterosexism and Perceived Stress Among Young LGBT Tunisians: Unveiling the Moderation Effects of Self-Esteem.

Int J Sex Health

September 2024

University of Sousse, Faculty of Medicine Ibn El-Jazzar, Farhat Hached Hospital, Department of Psychiatry, Research Laboratory LR12ES04, 4002, Sousse, Tunisia.

Background: LGBT individuals in Tunisia face discrimination and stigmatization due to prevailing socio-cultural and legal conditions which can negatively impact their mental health.

Aim: This study examined the relationship between perceived stress, heterosexist experiences, and self-esteem in a sample of LGBT young Tunisians.

Methods: We conducted an analytical cross-sectional study.

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COPD is a major public health problem due to its high morbidity and mortality. The evolution of COPD is marked by the occurrence of acute exacerbations (AECOPD). One of the major causes of AECOPD is non-adherence treatment.

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Effective communication of scientific knowledge plays a crucial role in the advancement of medical research and health care. Technological advancements have introduced large language models such as Chat Generative Pre-Trained Transformer (ChatGPT), powered by artificial intelligence (AI), which has already shown promise in revolutionizing medical writing. This study aimed to conduct a detailed evaluation of ChatGPT-3.

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Inner ear disorders, including sensorineural hearing loss, Meniere's disease, and vestibular neuritis, are prevalent conditions that significantly impact the quality of life. Despite their high incidence, the underlying pathophysiology of these disorders remains elusive, and current treatment options are often inadequate. Emerging evidence suggests that pericytes, a type of vascular mural cell specialized to maintain the integrity and function of the microvasculature, may play a crucial role in the development and progression of inner ear disorders.

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There is a lack of randomized clinical trials (RCTs) exploring the outcomes of cardiopulmonary rehabilitation programmes (CPRPs) on submaximal aerobic capacity of long COVID-19 patients (LC19Ps). This RCT aimed to evaluate the effect of an ambulatory CPRP on the 6-min walk test (6MWT) data (main outcome: 6-min walk distance (6MWD)) of LC19Ps. Conducted as a single-blinded RCT, the study included Tunisian LC19Ps with persistent dyspnoea (i.

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The World Health Organization's declaration of mpox (formerly known as monkeypox) as a public health emergency of international concern (PHEIC) in July 2022, followed by its resurgence in 2024, has sparked concerns about its potential impact on sports, especially contact sports such as football. Although mpox is not a pandemic (as of late September 2024), the coronavirus disease 2019 (COVID-19) experience offers valuable lessons for proactive planning in sports. Our conceptual framework has been designed to draw insightful lessons from the COVID-19 pandemic to assist sports organizations in planning for and preventing similar situations.

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Cranio-Spinal Irradiation in low-middle income setting: A dosimetric comparison and literature review.

Radiography (Lond)

October 2024

Department of Radiation Oncology, Salah Azaiz Institute, 1006, Tunis, Tunisia; Faculty of Medicine of Tunis, University Tunis El Manar, Tunis, 1068, Tunisia.

Article Synopsis
  • VMAT (Volumetric Modulated Arc Therapy) is a new technique for cranio-spinal irradiation (CSI) gaining traction in Tunisia, with a study comparing its dosimetric outcomes to 3DCRT (Three-Dimensional Conformal Radiotherapy).
  • The results showed that VMAT offers better target volume coverage and protection for some organs at risk, although it increases low-dose exposure to non-target tissue.
  • However, VMAT also requires longer treatment and beam-on times compared to 3DCRT, raising considerations for its implementation in low to middle-income countries.
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Mucopolysaccharidosis type I: founder effect of the p.P533R mutation in North Africa.

BMC Genomics

October 2024

Research Laboratory of Human Genome and Multifactorial Diseases (LR12ES07), Faculty of Pharmacy, University of Monastir, Monastir, Tunisia.

Background: Mucopolysaccharidosis type I is a lysosomal storage disease resulting from a deficiency in alpha-L-iduronidase (IDUA), which causes the accumulation of partially degraded dermatan sulfate and heparan sulfate. This retrospective study, spanning eight years, analyzed data from 45 MPSI patients. The report aimed to explore the potential origin of the p.

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Castleman's Disease Mimicking Malignant Submandibular Tumor: A Case Report.

Indian J Otolaryngol Head Neck Surg

October 2024

ENT Department and Cervical Surgery Farhat Hached Hospital, Medicine University, Sousse, Tunisia.

A submandibular mass can be attributed to a variety of potential diagnoses. We report a case of a 71-year-old man presenting with left submandibular swelling associated with multiple lymph nodes.All investigations were negative except for a suspected malignant submandibular tumour.

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Wet-cupping therapy (WCT) is one of the oldest known medical techniques, used as a traditional and complementary therapy with a wide application all around the world for general health. Research on the effects of WCT on sports performance are sparse and inconsistent. Thus, we aimed to explore the effects of WCT on repeated sprint ability, wellness, and exertion in young active males.

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High frequency of anti-Saccharomyces cerevisiae antibodies in chronic hepatitis C.

Arab J Gastroenterol

November 2024

Department of Immunology, Faculty of Pharmacy, Monastir University, Monastir, Tunisia; Laboratory of Immunology, Farhat Hached Hospital, Sousse, Tunisia.

Background And Study Aim: Chronic hepatitis C (CHC) is a liver disease caused by the hepatitis C virus. Anti-Saccharomyces cerevisiae (S. cerevisiae) antibodies (ASCA) are frequently reported in autoimmune diseases but rarely in viral infections.

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Unspecific back pain (UBP) has long puzzled medical professionals. Historically, back pain (BP) was often attributed to mystical causes, treated with incantations or herbal concoctions. The Middle Ages shifted towards empirical practices, though still intertwined with superstition, using methods like leeches and bloodletting.

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Article Synopsis
  • * Among the patients, there were six girls and one boy, with an average disease onset age of 8.16 years and a diagnosis delay of 8.8 months; most exhibited skin symptoms and muscle weakness.
  • * Treatment primarily involved oral corticosteroids, with varying outcomes: three patients improved, two experienced relapses, and one had a fatal outcome despite resistance to corticosteroids. *
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Effects of Inspiratory Muscle Training on Stress Urinary Incontinence in North African Women: A Randomized Controlled Trial.

Int Urogynecol J

October 2024

APERE, Exercise Physiology and Rehabilitation Laboratory, Picardie Jules Verne University, Sport Sciences Department, Avenue Paul Claudel, 80025, Amiens Cedex, France.

Introduction And Hypothesis: Pelvic floor muscles (PFMs) are involved in respiratory mechanisms. Additionally, stress urinary incontinence (SUI) can affect physical function. This randomized controlled trial was aimed at investigating the effects of inspiratory muscle training (IMT) on SUI severity, PFM function, and physical function in Tunisian women with SUI.

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Article Synopsis
  • Calcifying odontogenic cyst (COC), or Gorlin cyst, is a rare benign cyst mainly found in jawbones, making up less than 1% of all odontogenic cysts, and can be linked to tumors like odontomas.
  • A case study of an 18-year-old female revealed a painless lesion in the right mandibular bone, which, after surgical removal, was confirmed to be COC associated with a complex odontoma through histopathology.
  • COC typically occurs in young adults and is characterized by calcified ghost cells; treatment involves total enucleation with a good prognosis, but long-term follow-up is essential to monitor for recurrences.
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Non-islet cell tumor hypoglycemia (NICTH) is a rare paraneoplastic syndrome characterized by insulin-like growth factor-2 (IGF-2) release, often associated with diverse tumor types. Gastrointestinal stromal tumors (GISTs), sarcomatous lesions of the gastrointestinal tract, are rarely associated with NICTH. We present a unique case of a 58-year-old patient diagnosed with a GIST exhibiting recurrent hypoglycemia suggestive of NICTH.

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Follicular dendritic cell sarcoma (FDCS) is an extremely rare malignancy arising from follicular dendritic cells accounting for less than 0.4% of all soft tissue sarcomas. While it can manifest in various anatomical locations, its occurrence in the nasopharynx is particularly uncommon with only 10 reported cases in the English literature.

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