Comparison of the synthesis of the alpha-amylase enzyme by the native strain in immobilized and immersed cells.

Background And Objectives: The study focused on the amylase enzyme, widely used in the industrial starch liquefaction process. We looked into the best way to immobilize the native strain , which is the only alpha-amylase-producing bacterium, by trapping it in calcium alginate gel. This is a promising way to increase enzyme output.

Diagnostic Value of Hepatic Mast Cell Concentration (MCC) in NAFLD and NASH Severity and Fibrosis Grade.

Background & Objective: Mast cells play a role in the immune responses to fatty liver disease. The present study aimed to investigate the diagnostic value of hepatic mast cell concentration (MCC) in NAFLD and NASH severity and fibrosis grade.

Methods: The present cross-sectional unremarkable hepatic histology, NAFLD, or NASH cases were enrolled.

Green nitrogen and sulfur co-doped carbon dots derived from eggshell as a high performance aptasensing interface for non-invasive detection of metronidazole.

Background: The concentration monitoring of the banned metronidazole (MTZ) drug as the alarmed carcinogenic agent in human biofluids is medically essential. The electrochemical aptasensors are good candidates to overcome some presence challenges in the detection process.

Results: Herein, an electrochemical aptasensor based on nitrogen and sulfur co-doped carbon dots (NcS-CDs) has been developed for the high-sensitive detection of MTZ for the first time.

Improvement of the Gaussian mixture models' unsupervised learning method through the inclusion of dynamical systems for various types of nonlinear data.

Gaussian mixture models (GMM) with a modulating dynamical system (DS) approach is an unsupervised learning method, and it can estimate the distribution of given data or encoding trajectories in the input space. In this paper, a series of trajectories is considered for simulation, and the role of tuning parameters in the algorithm for both Gaussian function encoding and behavior of the dynamical system is obtained and compared. This algorithm divides the input space of the data into presupposed local regions and then in each local region of the data employs a dynamical system approach for tracking the major trajectories of the data.

Applicability of a green nanocomposite consists of reduced graphene oxide and β-cyclodextrin for electrochemical tracing of methadone in human biofluids validated by international greenness indexes.

Background: Detecting methadone (MET) is crucial due to its severe side effects.

Method: Herein, a green nanocomposite based on reduced graphene (rGO) and β-cyclodextrin (β-CD) has been introduced to modify a glassy carbon electrode (GCE) for real-time measurement of MET. This eco-friendly sensing interface has synergistically benefited from both advantages of rGO and β-CD including excellent electron transfer tunneling and surface area enhancement to selectively trap MET based on its shape and size.

Biosensors for early stroke detection.

This article aims to provide a comprehensive review of the latest advances in biosensor technology for early stroke diagnosis. Analyzing current research from authoritative databases highlights the significance of biosensors in improving stroke detection and treatment outcomes, discusses their diagnostic capabilities, and addresses the challenges that must be overcome for broader clinical application. This review utilizes updated information and valid research from ISI, Google Scholar, Science Direct, Scopus, and PubMed to examine recent developments in biosensors applicable to early stroke diagnosis.

Combined mindfulness-based stress reduction and physical activity improved psychological factors and sleep quality in patients with MDD: A randomized controlled trial study.

Non-pharmacological interventions are available to improve sleep quality including mindfulness-based stress reduction (MBSR) and physical activity (PA). The present study aimed to evaluate the effectiveness of the combination of MBSR and PA interventions as an augmentation to treatment as usual with sertraline to improve sleep and psychological factors among patients with MDD. Sixty-seven patients in outpatient care diagnosed with MDD for a minimum of 2 months (mean age: 35.

Synthesis and characterization of metal dithiocarbamate derivatives of (S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline.

Five metal dithiocarbamate complexes [M(PTHIQDTC)] [where PTHIQDTC is (S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline dithiocarbamate anion and M is Ni(II) (1), Sn(II) (2), Hg(II) (3), Pb(II) (4) and Zn(II) (5)] were synthesized from the reaction of MX (X is Cl for 1-3 and OAc for 4-5) with ligand of triethylammonium (S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline dithiocarbamate [EtNH][PTHIQDTC] in methanolic solution at room temperature. The five complexes were characterized by IR, H andC NMR, mass spectrometry, elemental analysis and TGA analysis. Recrystallization of [Zn(PTHIQDTC)] (5) in dimethylsulfoxide (DMSO) converts 5 to [Zn(PTHIQDTC)(DMSO)] (6).

The Association of Matrix Metalloproteinase-1, -2, -3, -7, and -13 Gene Polymorphisms With Peri-Implantitis in an Iranian Population: A Case-Control Study.

Objectives: Peri-implantitis (PI) is the most common biological issue surrounding dental implants. According to current knowledge, the aforementioned complication is not equally distributed across different populations, and gene polymorphisms might be one contributing factor. The current study aimed to examine the association between gene polymorphisms of matrix metalloproteinase- (MMP-) 1, -2, -3, -7, and -13 with PI in an Iranian demographic.

Simultaneous effects of high-speed circuit training (HSCT) and high-speed interval training (HSIT) on physical fitness and lung volumes of males after coronavirus disease.

Background: People who are quarantined after coronavirus disease experience immobility, obesity and changes in the cardiopulmonary system. We hypothesized that the concurrent use of high-speed circuit training (HSCT) and high-speed interval training (HSIT) can be used to improve physical fitness and respiratory functions.

Methodology: Physical education students (n = 65, 18-22 yrs.

Importance of LINC00852/miR-145-5p in breast cancer: a bioinformatics and experimental study.

Purpose: We aimed to examine the importance of an lncRNA, namely LINC00852, in the pathogenesis of breast cancer.

Materials And Methods: In the current study, we used several online tools to examine the importance of LINC00852 in breast cancer. Then, we examined these findings in 50 pairs of breast cancer tissues and adjacent non-cancerous ones.

The Effect of Corrective Exercises on Ground Reaction Forces in Male Students With Upper Crossed Syndrome During Throwing.

Purpose: Poor posture has a negative impact on physical capability and is associated with changes in biomechanics and motor control. The purpose of this study was to assess the effect of corrective exercises on ground reaction forces (GRFs) in male student handball players with upper crossed syndrome (UCS) during throwing.

Methods: Thirty male handball students with UCS participated in this single-blind randomized controlled trial (IRCT20200622047888N2; IR.

Electrochemical measurement of morphine using a sensor fabricated from the CuS/g-CN/Ag nanocomposite.

Morphine, as one of the most important narcotic drugs, significantly affects the nervous system and increases euphoria, which raises the likelihood of its misuse. Therefore, its measurement is of great importance. In this work, a new electrochemical sensor based on a nanocomposite of CuS/g-CN/AgNPs was developed for modifying Screen printed carbon electrodes (SPCEs) and used for the measurement of morphine through cyclic voltammetry and differential pulse voltammetry.

The Effects of Subjective Socioeconomic Status and Social Capital on Self-rated Health and Perceived Quality of Life: A Cross-sectional Survey-based Study in a Minority Group in Iran.

Objectives: The purpose of this study is to examine the impact of subjective socioeconomic status and social capital on self-rated health and quality of life among a minority group in Iran.

Methods: This cross-sectional study involved 800 individuals from a minority group in Iran. The sampling method was clustering, and data collection was conducted using a questionnaire.

Impact of chronic opioid on cognitive function and spermatogenesis in rat: An experimental study.

Background: Opioid analgesics like morphine and methadone are widely used for managing severe pain; however, concerns over their potential misuse and adverse effects on the brain and reproductive system are significant.

Objective: We aimed to investigate their impacts on spermatogenesis and cognitive function in male Norway rats.

Materials And Methods: In this experimental study, 36 male Norway rats (250-300 gr, 6 months old) were divided into 6 groups: low-dose morphine, high-dose morphine, low-dose methadone, high-dose methadone, positive control (received normal saline at 5 mg/kg), and negative control (received no treatment).

Co-morbid Insomnia and Sleep Apnea (COMISA) in a large sample of Iranian: prevalence and associations in a sleep clinic population.

Background: Sleep apnea (SA) and insomnia (INS) are prevalent sleep disorders among referrals to sleep clinics. People with comorbid insomnia and sleep apnea (COMISA) suffer both disorders simultaneously. The epidemiology of COMISA is not well known in the Middle East including Iran.

Cardioprotective effects of aerobic training in diabetic rats: Reducing cardiac apoptotic indices and oxidative stress for a healthier heart.

Background: The present study evaluated the effects of aerobic training with variable intensities on apoptotic indices of cardiac tissue in fatty diabetic rats.

Methods: Twenty-four male Wistar rats were randomly divided into non-diabetic (ND, n=8), trained diabetic (TD, n=8), and control diabetic (CD, n=8) groups. Following a high-fat dietary regimen, type 2 diabetes was induced by streptozotocin, with blood glucose levels above 300 mg/dL considered indicative of diabetes.

The effect of synbiotic coating of flaxseed mucilage-defatted rice bran carbohydrate on quality of dried mango, viability of subsp. BB12 on storage and simulating gastrointestinal condition.

In the present study, a synbiotic coating of flaxseed mucilage, defatted rice bran carbohydrate, and subsp. BB12 was fabricated for coating dried mango slices (M-P-C). The control samples contained only probiotic bacteria without coating (M-P).

Comparison of balance and proprioception of the shoulder joint in girls with and without upper cross syndrome.

Upper cross syndrome is one of the most common disorders of the upper part of body, often associated with abnormalities of forward head, forward shoulders, elevated and protracted of scapula, and increased thoracic kyphosis. Conducting research on upper cross syndrome, especially in girls, is of highly significant, considering this issue and lack of examination of complications and consequences of this syndrome; therefore, this study aims to compare the balance and proprioception of the shoulder joint in girls with and without upper cross syndrome.Method The statistical population included two groups of 10-12-year-old female students, i.

The effect of physical activity intervention on blood pressure in 18 low and middle-income countries: a systematic review and meta-analysis of randomized controlled trials.

Background: In especially, low and middle-income nations (LMICs), where healthcare access may be restricted, high blood pressure (BP) is a major risk factor for cardiovascular disease and stroke, both of which can even lead to death. Altering one's lifestyle, in conjunction with medical therapy, has been demonstrated to be effective in lowering BP. Recent research has shown that physical activity (PA), in a variety of guises and to varying degrees, can be an effective means of lowering BP.

Atomistic understanding on desalination performance of pristine graphenylene nanosheet membrane at high applied pressures.

Molecular dynamics (MD) simulations are conducted to assess pristine graphenylene membranes' effectiveness in seawater desalination, explicitly focusing on their salt rejection and water permeability capabilities. This study investigates the potential of the graphenylene for separation of the Na as monovalent cation, in order to evaluate its further application for separation of the other type of contaminants. To this end, the pristine graphenylene nanosheet is introduced into the simulation box which included the water molecules, sodium and chlorine ions.