10 results match your criteria: "Faculty of Medicine at University of Lisbon[Affiliation]"

PrOgnosis in Pulmonary Embolism (PoPE): 30-Day mortality risk score based on five admission parameters.

Rev Port Cardiol

January 2024

Cardiology Department, Hospital Prof. Doutor Fernando Fonseca, Amadora, Portugal; Advanced Cardiac Imaging Department, Barts Heart Centre, St Bartholomew's Hospital, London, UK; Institute of Cardiovascular Science, University College London, London, UK. Electronic address:

Introduction And Objective: Several scoring systems have been developed for risk stratification in patients with acute pulmonary embolism (PE). The Pulmonary Embolism Severity Index (PESI) and its simplified version (sPESI) are among the most used, however the high number of variables hinder its application. Our aim was to derive an easy-to-perform score based on simple parameters obtained at admission to predict 30-day mortality in acute PE patients.

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Article Synopsis
  • - Kounis syndrome is an acute coronary syndrome triggered by hypersensitivity reactions, leading to issues like coronary artery spasm and stent thrombosis due to mast-cell activation.
  • - A case is presented of a man who experienced a heart attack 20 minutes after receiving the COVID-19 vaccine, which was linked to previous reactions after an influenza vaccine, both containing polysorbate 80.
  • - This case highlights the importance of recognizing Kounis syndrome, especially as it can be life-threatening and often goes undiagnosed, emphasizing the need for proper diagnosis and future drug avoidance.
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Introduction And Objectives: Use of invasive physiological assessment in patients with coronary artery disease varies widely and is perceived to be low. We aimed to examine adoption rates as well as patterns and determinants of use in an unselected population undergoing invasive coronary angiography over a long time frame.

Methods: We retrospectively determined the per-procedure prevalence of physiological assessment in 40821 coronary cases performed between 2007 and 2018 in two large-volume centers.

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Introduction And Objectives: Use of invasive physiological assessment in patients with coronary artery disease varies widely and is perceived to be low. We aimed to examine adoption rates as well as patterns and determinants of use in an unselected population undergoing invasive coronary angiography over a long time frame.

Methods: We retrospectively determined the per-procedure prevalence of physiological assessment in 40821 coronary cases performed between 2007 and 2018 in two large-volume centers.

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Nonculprit lesions are frequently observed in patients with ST-segment elevation myocardial infarction. Results from recent randomized clinical trials suggest that complete revascularization after ST-segment elevation myocardial infarction improves outcomes. In this state-of-the-art paper, the authors review these trials and consider how best to determine which nonculprit lesions require revascularization and when this should be performed.

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Article Synopsis
  • The study investigates different cutoff values for the instantaneous wave-free ratio (iFR) in assessing nonculprit stenoses in patients with ST-segment elevation myocardial infarction.
  • It found that an iFR cutoff value of <0.90 is most effective for determining hemodynamic significance, showing high negative predictive value, especially at higher iFR thresholds.
  • These results suggest that using iFR <0.90 provides the best classification agreement between acute and follow-up assessments of nonculprit stenoses in this patient population.
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Importance: Approximately one-third of patients considered for coronary revascularization have diabetes, which is a major determinant of clinical outcomes, often influencing the choice of the revascularization strategy. The usefulness of fractional flow reserve (FFR) to guide treatment in this population is understudied and has been questioned.

Objective: To evaluate the usefulness and rate of major adverse cardiovascular events (MACE) of integrating FFR in management decisions for patients with diabetes who undergo coronary angiography.

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