6 results match your criteria: "Faculty of Medicine and Pharmacy Vrije Universiteit Brussel[Affiliation]"
Article Synopsis
- Half of the heart failure patients with preserved ejection fraction (HFpEF) remain undiagnosed with just resting evaluations, leading researchers to suggest exercise testing as a potential solution.
- A study involving 1,936 patients evaluated their exercise performance and the mean pulmonary artery pressure over cardiac output (mPAP/CO) slope to assess their HFpEF likelihood.
- Results indicated that 22% of patients had abnormal test results with a high mPAP/CO slope despite a negative diastolic stress test (DST), suggesting that this slope could be a key indicator of HFpEF, even when DST results are not conclusive.
The viscosity-enhancing effect of carob bean gum and sodium carboxymethylcellulose when added to infant formula.
Food Sci Nutr
April 2024
Laboratory of Pharmaceutical Technology, Department of Pharmaceutics Ghent University Ghent Belgium.
Article Synopsis
- The study examines the effects of carob bean gum and sodium carboxymethylcellulose as thickening agents in infant formula, highlighting significant increases in viscosity with minor dosage changes.
- Findings indicate that achieving the desired thickness requires careful dosing and preparation, including a recommended 30-minute wait time for optimal thickening with carob bean gum.
- The research underlines the necessity for parents to be educated on proper handling to ensure that the thickened formula meets the infant's feeding needs, taking into account the variability in viscosity and appropriate bottle teat sizes.
Genomic monitoring of SARS-CoV-2 variants using sentinel SARI hospital surveillance.
Influenza Other Respir Viruses
October 2023
Viral Diseases, National Influenza Centre, Scientific Directorate of Infectious Diseases in Humans Sciensano Ukkel Belgium.
Background: To support the COVID-19 pandemic response, many countries, including Belgium, implemented baseline genomic surveillance (BGS) programs aiming to early detect and characterize new SARS-CoV-2 variants. In parallel, Belgium maintained a sentinel network of six hospitals that samples patients with severe acute respiratory infections (SARI) and integrated SARS-CoV-2 detection within a broader range of respiratory pathogens. We evaluate the ability of the SARI surveillance to monitor general trends and early signals of viral genetic evolution of SARS-CoV-2 and compare it with the BGS as a reference model.
View Article and Find Full Text PDFReal-World Effectiveness, Safety, and Health-Related Quality of Life in Patients Receiving Adjuvant Nivolumab for Melanoma in Belgium and Luxembourg: Results of PRESERV MEL.
Cancers (Basel)
September 2023
Department of Medical Oncology, Universitair Ziekenhuis Brussel, 1090 Brussels, Belgium.
Article Synopsis
- Nivolumab is now an approved immunotherapy for adjuvant treatment in patients with completely resected stage III or IV melanoma, and the PRESERV MEL study seeks to evaluate its real-world effectiveness and safety in Belgium and Luxembourg.* -
- The study enrolled 152 patients over a 2-year period and includes both prospective and retrospective data, with key outcomes measured over a follow-up duration of at least 11.4 months.* -
- Results show that at 12 and 18 months, the relapse-free survival rates were 74.7% and 68.4%, indicating promising initial outcomes for patients treated with nivolumab.*
Fast Helical Tomotherapy in a head and neck cancer planning study: is time priceless?
Radiat Oncol
December 2015
Radiotherapy UZ Brussel, Faculty of Medicine and Pharmacy Vrije Universiteit Brussel, Brussels, Belgium.
Background: The last few years, in radiotherapy there has been a growing focus on speed of treatment delivery (largely driven by economical and commercial interests). This study investigates the influence of treatment time on plan quality for helical tomotherapy (HT), using delivery times with Volumetric Modulated Arc Therapy (VMAT; Rapid Arc [RA]) as reference.
Methods: In a previous study, double arc RA (Eclipse) and standard HT plans (TomoHD™) were created for five oropharyngeal cancer patients and reported according to ICRU 83 guidelines.
Evaluation of the optimal combinations of modulation factor and pitch for Helical TomoTherapy plans made with TomoEdge using Pareto optimal fronts.
Radiat Oncol
September 2015
Radiotherapy UZ Brussel, Faculty of Medicine and Pharmacy Vrije Universiteit Brussel, Brussels, Belgium.
Background: Modulation factor (MF) and pitch have an impact on Helical TomoTherapy (HT) plan quality and HT users mostly use vendor-recommended settings. This study analyses the effect of these two parameters on both plan quality and treatment time for plans made with TomoEdge planning software by using the concept of Pareto optimal fronts.
Methods: More than 450 plans with different combinations of pitch [0.