Massive hydropyonephrosis on pediatric patient: A case report of management and source control.

Introduction And Importance: Dilation and stretching of the collecting system of the kidney due to obstruction of urine flow is called hydronephrosis. This case may be accompanied by the presence of pus known as pyonephrosis. This case report reporting massive pyonephrosis in pediatrics related to management and source of control.

Co-occurrence of frailty, possible sarcopenia, and malnutrition in community-dwelling older outpatients: a multicentre observational study.

Background: The co-occurrence of frailty, sarcopenia and malnutrition has been well studied in inpatient and nursing home settings, which are associated with a higher risk of all-cause mortality. However, multicentre data from community-dwelling outpatient settings are lacking. Therefore, we aimed to find the prevalence of frailty, possible sarcopenia and malnutrition, their overlap, and the associated factors in community-dwelling older outpatients.

Strategic vaccination responses to Chikungunya outbreaks in Rome: Insights from a dynamic transmission model.

Background: Chikungunya virus (CHIKV) outbreaks, driven by the expanding habitat of the Aedes albopictus mosquito and global climate change, pose a significant threat to public health. Our study evaluates the effectiveness of emergency vaccination using a dynamic disease transmission model for a potential large-scale outbreak in Rome, Italy.

Methods: The model incorporates a susceptible-exposed-infected-recovered (SEIR) framework for human and mosquito populations, taking into account temperature-dependent mosquito lifecycle dynamics, human-mosquito interactions, and various vaccination scenarios.

HYDROCEPHALUS AND CRANIOSYNOSTOSIS IN PAEDIATRICS: COEXISTENCE OF TWO PHENOMENA.

Background: Here, the authors describe their institutional experience managing patients who had hydrocephalus and craniosynostosis regarding their pre-operative and post-operative data.

Methods: The study was conducted in the Neurosurgery Department, Dr. Soetomo Academic General Hospital, Surabaya, Indonesia.

Intrapulmonary cavitating solitary fibrous tumor: A rare case report.

Solitary fibrous tumor (SFT) is a rare mesenchymal tumor that affects most commonly in the sixth or seventh decade of life. They account for less than 2% of all soft tissue tumors. In the thoracic region, it primarily appears in the pleura and rarely in the intrapulmonary.

Outcome of delayed presentation in patients with giant renal cell carcinoma: A case report.

Introduction And Importance: Renal cell carcinoma (RCC) is a common form of malignancy that causes many deaths worldwide. One of the RCC cases that is challenging and requires proper treatment is a large tumor. This report explores the delayed presentation and treatment of giant RCC.

Challenges and Strategies for Controlling Indonesia's Emerging and Re-Emerging Infection Diseases (EID-REIDs).

This review aims to highlight the occurrences of several emerging and re-emerging infectious diseases, particularly 13 types under surveillance of Indonesia's emerging contagious disease task force. These diseases are considered potentially epidemic, due to the nature of tropical climate and high humidity of Indonesia's area. Several factors contribute to the emergence of these diseases: in conjunction with human behavior.

Analysis of angiotensin II type 1 receptor and osteoprotegerin gene polymorphism on the risk of cardiovascular mortality risk and progressivity of chronic kidney disease.

Background: Chronic kidney disease (CKD) is a significant global public health issue with increased risk of atherosclerotic cardiovascular disease (ASCVD) and cardiovascular mortality. Single nucleotide polymorphisms (SNPs) on angiotensin II type 1 receptor (AT1R) A1166C and osteoprotegerin (OPG) C950T gene have received significant attention as a genetic risk factor for cardiovascular disease and CKD.

Methods: This was a cross-sectional study involving 75 adults with CKD recruited from Nephrology Outpatient Clinics of Universitas Airlangga Hospital, Surabaya, Indonesia.

Effectiveness of Bilayer Scaffold Containing Chitosan/Gelatin/Diclofenac and Bovine Hydroxyapatite on Cartilage/Subchondral Regeneration in Rabbit Joint Defect Models.

Subchondral defects are often caused by trauma involving cartilage damage, leading to subsequent damage to the underlying bone, specifically the subchondral region. Bilayer scaffolds made from biomaterials, such as bovine hydroxyapatite, possess biocompatible and biodegradable properties that mimic the natural environmental conditions of target tissues so that they can support the formation of new tissues. On the other side, diclofenac as an anti-inflammatory drug potentiates to inhibit the inflammatory excess regarding the damage.

Unilateral secondary middle turbinate and ipsilateral bifid inferior turbinate with presence of uncinate process: Is it true bifid inferior turbinate?

Anatomical variations of the nasal turbinate, such as secondary middle turbinate (SMT) and bifid inferior turbinate (BIT), are sporadic. In most cases, SMT and BIT are generally bilateral. Moreover, the uncinate process is unusual in BIT because it is widely acknowledged that BIT could be an abnormality of the uncinate process.

Correlation Between Insulin Resistance and Psoriatic Arthritis Disease Activity: A Cross-Sectional Study.

Objectives: Most psoriatic arthritis (PsA) research and studies focus solely on the skin and joint manifestations, but there is also an increased risk of metabolic disorders, including insulin resistance (IR). This study aims to discover the relationship between IR and disease activity (DA) in PsA and its phenotype.

Materials And Methods: Patients with PsA classified using the CASPAR criteria with the disease activity was measured using the DAPSA score, and IR was identified as an elevated HOMA-IR of >2.

White matter abnormalities in aneurysmal and angiographically negative subarachnoid hemorrhage: A diffusion kurtosis imaging study.

Objective: Aneurysmal subarachnoid hemorrhage (aSAH) and angiographically negative subarachnoid hemorrhage (anSAH) cause an abrupt rise in intracranial pressure, resulting in shearing forces, causing damage to the white matter tracts. This study aims to investigate whole-brain white matter abnormalities with diffusion kurtosis imaging (DKI) after both aSAH and anSAH and explores whether these abnormalities are associated with impaired cognitive functioning.

Methods: Five months post-ictus, 34 patients with aSAH, 24 patients with anSAH and 17 healthy controls (HC) underwent DKI MRI scanning and neuropsychological assessment (measuring verbal memory, psychomotor speed, executive control, and social cognition).

Global Globin Network and adopting genomic variant database requirements for thalassemia.

Thalassemia is one of the most prevalent monogenic disorders in low- and middle-income countries (LMICs). There are an estimated 270 million carriers of hemoglobinopathies (abnormal hemoglobins and/or thalassemia) worldwide, necessitating global methods and solutions for effective and optimal therapy. LMICs are disproportionately impacted by thalassemia, and due to disparities in genomics awareness and diagnostic resources, certain LMICs lag behind high-income countries (HICs).

The predicting formula and scoring system for cardiac iron overload for thalassaemia children: Study from a middle-income country.

Magnetic resonance imaging T2* screening is the gold standard for detecting cardiac iron overload in thalassemia, but its implementation in Indonesia is limited by the high costs. A predicting formula and scoring system based on low-cost investigations is needed. This cross-sectional study was conducted among thalassemia aged 6-18 years at Rumah Sakit Anak dan Bunda RSAB Harapan Kita Indonesia, during October 2017 to April 2019.

Unusual radiologic imaging in juvenile granulosa cell tumor with precocious puberty: A unilocular cyst.

Juvenile Granulosa Cell Tumor (JGCT) represents 5% of all granulosa cell cancers. Precocious puberty is a frequent feature of this tumor. A 2-year and 2-month-old girl was referred with a diagnosis of suspected ovarian cancer, dysfunctional uterine bleeding, and precocious puberty.

Association between objectively measured protein intake and muscle status, health-related quality of life, and mortality in hemodialysis patients.

Background: Protein intake is known to be associated with muscle mass, health-related quality of life (HRQoL), and mortality in patients with stage 5 chronic kidney disease undergoing dialysis. However, most studies evaluated protein intake based on 24 h dietary recall or food frequency questionnaire, and these methods are prone to bias. Therefore, this study aimed to evaluate the association of objectively measured protein intake with muscle mass and strength, HRQoL, and mortality.

Minimal invasive management for untreated high-grade renal trauma and its complication: A case report.

Introduction And Importance: Renal trauma is a common and associated complication of abdominal trauma. Although there is consensus that most high-grade injuries require surgical exploration, nonoperative management remains a viable approach. We aim to report case reports of four cases of nonoperative isolated high-grade blunt renal trauma in adults, followed by a literature review.

Management of high-grade kidney trauma on bilateral polycystic kidney disease: A case report.

Background: The kidneys are the genitourinary organs most susceptible to trauma. One case is high-grade kidney trauma that can lead to kidney failure, such as Polycystic Kidney Disease (PKD). Here, we report a case of high-grade kidney trauma on PKD.

Apical tubular complement activation and the loss of kidney function in proteinuric kidney diseases.

Many kidney diseases are associated with proteinuria. Since proteinuria is independently associated with kidney function loss, anti-proteinuric medication, often in combination with dietary salt restriction, comprises a major cornerstone in the prevention of progressive kidney failure. Nevertheless, complete remission of proteinuria is very difficult to achieve, and most patients with persistent proteinuria slowly progress toward kidney failure.