24 results match your criteria: "Faculty of Medicine Prince of Songkla University[Affiliation]"

Paracrine role of endothelial IGF-1 receptor in depot-specific adipose tissue adaptation in male mice.

Nat Commun

January 2025

Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, UK.

During recent decades, changes in lifestyle have led to widespread nutritional obesity and its related complications. Remodelling adipose tissue as a therapeutic goal for obesity and its complications has attracted much attention and continues to be actively explored. The endothelium lines all blood vessels and is close to all cells, including adipocytes.

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Background: To determine the prognostic value of left atrial strain (LAS) using cardiac magnetic resonance for predicting death, heart failure, and ischemic stroke in patients with known or suspected coronary artery disease with preserved left ventricular systolic function and no prior history of ischemic stroke, heart failure, or atrial fibrillation.

Methods And Results: This retrospective cohort analysis included patients referred for stress cardiac magnetic resonance or myocardial viability studies between September 2017 and December 2019. Patients with impaired left ventricular systolic function (<50%) or a history of atrial fibrillation, stroke, or heart failure were excluded.

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Article Synopsis
  • - The study investigated how different success definitions for percutaneous balloon mitral valvuloplasty (PBMV) affect long-term outcomes in patients with severe rheumatic mitral stenosis.
  • - Researchers analyzed three success criteria related to mitral valve area (MVA) and mitral regurgitation (MR) and found that achieving any of these definitions was linked to a lower risk of adverse outcomes like mortality and the need for additional heart procedures.
  • - All three success definitions were shown to significantly impact patient prognosis, with the most favorable outcomes occurring in patients with an MVA of at least 1.5 cm and controlled MR levels.
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Effectiveness of motor imagery on sports performance in football players: A randomised control trial.

Hong Kong Physiother J

June 2024

Physical Therapy Department, Trang Hospital, 69 Khuan Han Road, Tambon Thap Thiang, Mueang Trang District, Trang 92000, Thailand.

Background: Nowadays, the development of training programs for speed, agility and reaction time responses in football players is increasing widely. Motor imagery is a new method that uses collateral with physical training. However, there is still a scarcity of evidence concerning the addition of motor imagery protocol to routine training programs.

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Background And Aims: Knee support, frequently made from sponge, is used to reduce injury. Sponge has less elasticity and durability compared with natural rubber. To our knowledge, there was no study that demonstrated the effectiveness of natural rubber and sponge in prevention of injury in children with bleeding disorders.

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Article Synopsis
  • Lazertinib is a new targeted therapy for non-small cell lung cancer (NSCLC) that has shown better efficacy than gefitinib in a study focused on Asian patients with specific EGFR mutations.
  • The LASER301 phase 3 study found that patients receiving lazertinib had a significantly longer progression-free survival (20.6 months) compared to those on gefitinib (9.7 months).
  • Both medications had similar safety profiles, with only slight differences in adverse events leading to discontinuation, making lazertinib a promising option for treating these patients.
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Objective: The advantages of laser stapedotomy are less trauma and more precise and minimally invasive techniques; however, the potential risk of overheating from the laser combined with the endoscope tip must be considered. This study aimed to assess the efficacy and safety of diode lasers for endoscopic stapes surgery.

Methods: A retrospective review of 56 patients with otosclerosis who underwent primary endoscopic stapedotomy with a diode laser from 2017 to 2020 was conducted.

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Alveolar capillary dysplasia with misalignment of the pulmonary veins (ACDMPV) is a rare congenital diffuse lung disorder, with a fatal course during the neonatal period. We describe an 18-month-old boy who presented with respiratory syncytial virus pneumonia and pulmonary hypertensive crisis requiring extracorporeal membrane oxygenation. Exome sequencing revealed a frameshift variant, NM_001451.

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Objectives: Parotidectomy increases childhood challenges. This study aimed to determine the clinical profiles, investigations, and outcomes of pediatric patients who had undergone parotidectomy.

Methods: A multicenter retrospective review of parotidectomy in pediatric patients between 2007 and 2020.

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Introduction: Lymphocyte-to-monocyte ratio (LMR) has been reported as a prognostic factor in many cancers but the data are to date limited for its use in oral cavity cancer. The purpose of this study was to evaluate the prognostic value of LMR in advanced-stage oral cavity cancer.

Methods: Data from 211 advanced-stage oral cancer patients treated with curative intent between January 2009 and December 2015 were obtained from the hospital information system.

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Background And Aims: Prothrombin induced by vitamin K absence-II (PIVKA-II) is a serum biomarker linked to hepatocellular carcinoma (HCC), showing superiority to alpha-fetoprotein (AFP) for early disease detection. We aimed to assess the clinical and analytical performance of the Elecsys® PIVKA-II immunoassay in diagnosing HCC and evaluate PIVKA-II's technical performance.

Methods: Serum samples from adult cases (i.

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Article Synopsis
  • The study focused on acute-on-chronic liver failure (ACLF) in Thailand, aiming to collect epidemiological data and validate a scoring system to predict mortality rates among affected patients.
  • The research included data from 638 hospitalized patients, revealing a 54% incidence of ACLF, primarily due to alcoholism and sepsis, with significant differences in 30-day mortality rates between ACLF (58%) and acute decompensated liver disease (46%).
  • Results showed that the CLIF-SOFA score was effective in predicting mortality risk in ACLF patients, and those with multiple organ failures faced higher short-term mortality.
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The reconstruction of high-level bile duct injury is challenging because exposure of the hilar area is limited and sometimes inaccessible by the Hepp-Couinaud approach. We describe a maneuver for total hilar exposure to perform complex bile duct injury reconstruction. After adhesions surrounding the liver are divided, intraoperative ultrasonography is used to delineate the hilar and intrahepatic biliary anatomy.

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Aims: Persistent and permanent atrial fibrillation (AF) often occurs in the presence of multiple comorbidities and is linked to adverse outcomes. It is unclear whether the sustained pattern of AF itself is prognostic or if it is confounded by underlying comorbidities. Here, we tested the association between the temporal patterns of AF and the risks of ischemic stroke and all-cause mortality.

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Objective: The decision regarding whether to perform a liver biopsy in patients with cirrhosis and clinically suspected autoimmune hepatitis (AIH) remains a challenge. This study aimed to assess the utility and complications of percutaneous liver biopsy in cirrhosis for differentiating AIH from other liver conditions.

Methods: A clinicopathological database of patients undergoing percutaneous liver biopsies for suspected AIH (unexplained hepatitis with elevated γ-globulin and autoantibody seropositivity) was reviewed to identify patients presenting with cirrhosis.

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Background: Nasal irrigation is widely used as an adjunctive treatment for rhinosinusitis. However, there is little information available regarding the efficacy of the devices used in this procedure. The objective of this study was thus to evaluate the effectiveness of nasal irrigation devices based on the experiences of patients with rhinosinusitis.

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Poroma, a benign sweat tumor, commonly presents with a nontender papule on the extremities. It can appear with a blinking light appearance on dermoscopy in real time.

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Objective: To compare the pregnancy outcome between pregnancies affected and not affected by thalassemia trait.

Methods: A retrospective case-control cohort study was conducted on singleton pregnant women who attended antenatal care and delivered at Songklanagarind Hospital. All of the participating thalassemia trait pregnant women were diagnosed based on hemoglobin typing and/or DNA analysis.

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Vascular involvement in neurofibromatosis type 1 is rare but has the potential to be fatal. We report a case of a patient with spontaneous rupture of a left intercostal artery aneurysm, which presented as a massive left hemothorax and was successfully treated by transarterial coil embolization.

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Fragile X syndrome (FXS) is the most common form of inherited mental retardation. We screened for FXS in 237 Thai males (age < or = 15 years) with developmental delay of unknown cause. We found 16 (6.

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