188 results match your criteria: "Faculty of Medicine Hospital[Affiliation]"

Evaluation of the association of mucosa-associated invariant T (MAIT) cells with childhood asthma.

Turk J Med Sci

December 2024

Division of Pediatric Pulmonology, Department of Pediatrics, Faculty of Medicine, İstinye University, İstanbul, Turkiye.

Background/aim: Innate-like T lymphocytes are a recently defined group of T cells comprising mainly mucosa-associated invariant T (MAIT) cells. The relationship between MAIT cells and childhood asthma is controversial. In this study, we aimed to determine the role of MAIT cells in patients with allergic asthma (AA) and nonallergic asthma (NAA).

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Background: Triple rule-out computed tomography angiography (CTA) provides imaging of the coronary arteries, pulmonary arteries, and thoracic aorta filled with contrast material (CM) to exclude or diagnose the pathologies of these three systems. Although dual rule-out adapted to exclude aortic and pulmonary pathologies. Iodinated CM may result in contrast-induced nephropathy, which lengthens hospital stay.

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Background: Restriction of shoulder movements in frozen shoulder may negatively affect individual's daily living activities. The effect of the virtual reality (VR)-based exercise program, which is an innovative application and has been used in the field of physiotherapy in recent years, is unknown on patients diagnosed with frozen shoulder.

Objective: This study was conducted to determine the effects of a VR-based exercise program provided to patients with frozen shoulder on their pain, joint motion, and quality of life.

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Background/objectives: After the earthquakes in Turkey, many citizens were injured, and a long ongoing process requiring physiological and psychological treatments began. The aim of this study was to observe the pain and psychological changes in earthquake victims in light of the QoR-15 score.

Methods: After approval by the local ethics committee (Decision No.

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Article Synopsis
  • Lung cancer is a significant issue for patients with Idiopathic Pulmonary Fibrosis (IPF), but there is limited research on those with non-IPF Pulmonary Fibrosis (PF); this study compares the two groups in terms of characteristics and survival.
  • The study analyzed data from 251 patients diagnosed with lung cancer between 2010 and 2022, finding that most were elderly men with a high smoking rate, and differing patterns of lung imaging between the two groups.
  • Both IPF-LC and non-IPF PF-LC patients had high 5-year mortality rates around 64%, with the shortest survival noted in non-IPF PF patients with unclassified PF.
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The General Practitioner Assessment of Cognition (GPCOG) was explicitly developed as a brief cognitive screening tool for general practitioners. It consists of a patient section testing cognition and an informant section asking historical questions. This study aimed to test the validity and reliability of the Turkish version of GPCOG-Tr on older Turkish adults.

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Background: Diagnosing anaphylaxis in children within the first 2 years of life can be difficult due to the often confusing and nonspecific signs and symptoms.

Objective: This study focuses on the phenotype of anaphylaxis in children within the first 2 years of life and aims to increase awareness of anaphylaxis in this age group.

Methods: The study included children between 0 and 2 years who were diagnosed as having anaphylaxis by pediatric allergists in 11 tertiary hospitals.

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Aim: To determine the effect of kangaroo mother care (KMC) on perfusion index, heart rate, and oxygen saturation in premature infants who were discharged early and admitted to the neonatal intensive care unit (NICU) in the following days.

Methods: This study has a randomized controlled experimental design and uses a pretest-posttest control group model. This study included infants between December 2019 and December 2020 who were discharged early and subsequently admitted to the NICU.

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Investigation of Colistin resistance and method comparison in Klebsiella pneumoniae strains.

Diagn Microbiol Infect Dis

January 2025

Ege University Faculty of Medicine Hospital, Department of Medical Microbiology 35100, Bornova, İzmir, Türkiye.

Purpose: This study aimed to assess the prevalence of colistin resistance in the study group and compare alternative methods with the gold standard. It sought to evaluate the prevalence of plasmid-mediated colistin resistance genes.

Material And Methods: The colistin susceptibility of 151 K.

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Aim: This study aims to examine the influence of single and double-shift work schedules on hand function and cognitive capacities, specifically working memory, attention, and response time in nurses.

Background: Shift work, particularly in extended formats, is known to affect various physical and cognitive functions critical to nursing duties. Understanding these impacts is vital for managing nurse schedules to minimize health risks and maximize performance.

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Background: Achalasia is a rare neurodegenerative disease of the esophagus that causes impaired esophageal peristalsis and the inability of the lower esophageal sphincter (LES) to relax. This results in symptoms such as dysphagia, regurgitation, chest pain, and weight loss. Among the treatment options, Laparoscopic Heller Myotomy (LHM), Endoscopic Balloon Dilation (EBD), and Peroral Endoscopic Myotomy (POEM) are commonly used methods.

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Correction to: Eur Rev Med Pharmacol Sci 2021; 25 (18): 5801-5806-DOI: 10.26355/eurrev_202109_26798-PMID: 34604971 published online on September 30, 2021. The methodology section of this research article incorrectly stated that the lexi-interact checker program is freely accessible.

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Depending on the total amount of fluid, changes occur in the amount of fluid in the peripheral area. The aim of this study was to observe the differences caused by hemodynamic changes after lateral sagittal infraclavicular block (LS-ICB) according to the inferior vena cava collapsibility index (VCI-CI). In this prospective, observational study (Clinical Trial Number: NCT05968105), patients undergoing elective hand and wrist surgery with LS-ICB were classified according to VCI-CI, with Group 1 defined as inferior vena cava (VCI) diameter < 1.

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Article Synopsis
  • Immunoglobulin-G4 (IgG4)-related disease is a rare fibro-inflammatory condition that can impact multiple organs simultaneously or at different times, often presenting with tumor-like organ growth.
  • Key affected organs include the lacrimal glands, salivary glands, pancreas, and more, with distinctive histopathological features like dense IgG4-positive plasma cells and storiform fibrosis.
  • The disease has an estimated incidence of less than 1 in 100,000 people globally, and a specific case of IgG4-related vasculitis was diagnosed through lung fine needle aspiration biopsy, highlighting its rarity in medical literature.
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  • The study evaluated five different scoring systems (FGSI, UFGSI, ACCI, qSOFA, LRINEC) to predict outcomes in patients with Fournier gangrene, analyzing data from 311 patients between 2010 and 2024.
  • Univariate and multivariate analyses showed that UFGSI and FGSI were the most effective scoring systems in predicting mortality, with higher values seen in non-survivor patients.
  • ROC analysis determined optimal cut-off values for each scoring system, with UFGSI proving to be the most accurate for predicting mortality, achieving 84% sensitivity and 97% specificity at a score ≥12.
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Oral and Nasal Myiasis in Two Patients Hospitalized in the Intensive Care Unit: Diagnosis and Clinical Significance of Cases.

Indian J Otolaryngol Head Neck Surg

October 2024

Faculty of Medicine Hospital, Department of Parasitology Tokat, Tokat Gaziosmanpaşa University, PO Box 60030, Tokat, 60100 Turkey.

Article Synopsis
  • Myiasis is a disease caused by fly larvae living in the bodies of people or animals, which can happen if hygiene is poor.
  • Two elderly patients in an intensive care unit had fly larvae found in their mouths and noses, showing the importance of cleanliness in hospitals.
  • Doctors removed the larvae from the patients and treated them, highlighting that myiasis is rare but can be serious for people who are already sick or have weak immune systems.
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  • Surgery is often considered for patients with mallet fractures, especially if there is significant joint displacement or subluxation, but outcomes can be unsatisfactory and the best surgical approach is debatable.
  • The study aimed to analyze the angle of the fracture line (FLA) in relation to the long axis of the distal phalanx and how it might aid in choosing treatment strategies.
  • Researchers found a consistent method to measure the FLA and noted a strong correlation in measurements; however, no direct link was observed between the FLA and the percentage of joint surface involved, suggesting that FLA could be useful in treatment decisions.
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Objective: Developmental care for newborns with congenital heart disease (CHD) improves cardiac and respiratory patterns. According to the American Heart Association, developmental care in newborns with CHD is important for improving neurodevelopmental outcomes. This study aimed to evaluate the validity and reliability of the Turkish version of the Developmental Care Scale for Neonates with Congenital Heart Disease.

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Rare diseases (RDs), important for children and families, have been poorly studied in Turkey. This study aimed to describe the experiences and needs of mothers whose children have RDs from the perspectives of their mothers. In-depth interviews were held with the mothers of 16 children followed up in the Pediatric Nutrition and Metabolism Outpatient Clinic of a University Hospital.

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Background: Behçet's disease (BD) pathogenesis involves severe outcomes such as blindness, central nervous system manifestations, and deep venous thrombosis that impacts systemic and local inflammatory changes. We tested the hypothesis that BD negatively affects gingival health and increases the severity of gingivitis.

Methods: The study included 37 BD patients with gingivitis without any sign of periodontitis.

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A rare cause of immune dysregulation, prolidase deficiency: a case report and review of the literature.

Immunol Res

December 2024

Division of Pediatric Genetics, Department of Child Health and Diseases, Faculty of Medicine Hospital, Dokuz Eylul University, Izmir, Turkey.

We report a pediatric patient with prolidase deficiency, caused by a mutation in the PEPD gene, which encodes the enzyme prolidase D, with a lupus-like clinic and marked dysmorphic features along with pulmonary, neurological, skeletal, and immune system involvement. In addition to being the first known case in the literature where Friedrich's ataxia and prolidase deficiency were observed together, we aimed to highlight that this diagnosis should be considered in patients with autoimmunity and additional systemic findings such as treatment-resistant skin lesions, intellectual disability, and pulmonary manifestations. Furthermore, we sought to compare this case with others documented in the literature.

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Article Synopsis
  • The study aimed to see how well special skin care and a hydrocolloid dressing can prevent injuries caused by nasogastric (NG) tubes in patients.
  • 102 patients were tested in three groups: one with hydrocolloid dressing, one with skin care, and a control group with no treatment.
  • The results showed that none of the patients with the hydrocolloid dressing got injuries, while a lot in the other groups did, proving the dressing is more effective than just skin care.
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Background: Vocal fold nodules are most common in women and patients with vocal fold nodules represent the largest group in voice clinics. The prevalence of vocal fold nodules is particularly high in professions where the voice is used on a regular basis. The quality of the voice is influenced by a number of factors, including temperament, stress, and emotional state.

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Background: To reduce maternal-fetal morbidity and mortality, it is becoming increasingly important for anesthetists to understand and implement enhanced recovery after surgery (ERAS) cesarean delivery guidelines. Our aim was to reveal the knowledge of anesthesia assistants in Turkey about ERAS during cesarean delivery and to increase their awareness of ERAS.

Methods: This descriptive study was conducted in the city of Isparta, Turkey in 2023.

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Article Synopsis
  • Enteric viruses are the main cause of diarrhea in children under 5, with rotavirus being a well-researched culprit in Mozambique, though other viruses lack data post-vaccine.
  • The study investigated the prevalence of norovirus GI and GII, adenovirus 40/41, astrovirus, and sapovirus in children with varying severity of diarrhea before and after the introduction of the rotavirus vaccine.
  • Results showed that all viruses, except norovirus GI, were detected more frequently after the vaccine's introduction, highlighting the importance of ongoing monitoring for these viruses to improve disease prevention strategies.
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