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Evaluation of IVIM in the Spinal Cord of Multiple Sclerosis Patients.

Radiol Technol

March 2024

Christine Heales, PhD, works for the Department of Health and Care Professions, Faculty of Health and Life Sciences at the University of Exeter, United Kingdom.

Purpose: To evaluate the ability of intravoxel incoherent motion (IVIM), a perfusion-weighted imaging technique, to differentiate microcirculation changes in the spinal cord of patients with multiple sclerosis (MS) compared with healthy individuals.

Methods: Fifteen healthy individuals and 15 individuals with MS underwent IVIM magnetic resonance (MR) imaging using a 3 T scanner with 2-D axial gradient recalled echo and 2-D axial diffusion-weighted imaging (DWI) sequences. The MR images underwent segmentation to produce white matter and gray matter regions of interest.

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