1 results match your criteria: "Faculty of Health Sciences University of the Free State Bloemfontein South Africa.[Affiliation]"
The roles of patient-derived xenograft models and artificial intelligence toward precision medicine.
MedComm (2020)
October 2024
Department of Chemical Pathology, School of Pathology, Office of the Dean, Faculty of Health Sciences University of the Free State Bloemfontein South Africa.
Article Synopsis
- Patient-derived xenografts (PDX) involve transplanting patient tumors into mice, providing better disease models compared to traditional methods due to their stability and resemblance to the original tumors.
- While PDX models have great potential for advancing cancer research and personalizing treatment, challenges like high costs, variability in results, and the need for further understanding of their predictive power remain.
- The review discusses the methodologies for creating PDX models, their benefits in cancer studies, and highlights the incorporation of AI and machine learning to enhance drug testing efficiency and deepen insights into cancer biology.