A bridge between worlds: Embedding research in telepractice co-design with disability community.

Introduction: Co-production approaches are increasingly being advocated for as a way of addressing the research translatory gap while including patient and public involvement in development of services they access, and particularly in disability service provision. Embedded research (ER) is a method which integrates the researcher within the target organization to better facilitate both co-production of research outputs and the reduction of the research translation gap. The aim of this reflection is to better understand the commonalities and differences between ER in a disability context to accounts published in academic literature.

DNA Barcoding for the Identification of Adult Mosquitoes (Diptera: Culicidae) in Western Australia.

Precise mosquito identification is integral to effective arbovirus surveillance. Nonetheless, the conventional morphological approach to identifying mosquito species is laborious, demands expertise and presents challenges when specimens are damaged. DNA barcoding offers a promising alternative, surmounting challenges inherent in morphological identification.

Hepatic steatosis: Qualitative and quantitative sonographic assessment in comparison to histology.

Introduction: Globally, B-mode ultrasound is the most common modality used for the diagnosis of hepatic steatosis. We aimed to assess the correlation between qualitative liver ultrasound parameters, attenuation imaging (ATI) and histopathology-diagnosed steatosis grade obtained from liver biopsy. Our secondary aim was to examine the interobserver variability of qualitative ultrasound features.

PROTOCOL: Factors influencing the implementation of non-pharmacological interventions for behaviours and psychological symptoms of dementia in residential aged care homes: A systematic review and qualitative evidence synthesis.

This is a protocol for a Cochrane Review. The objectives are as follows. This paper aims to describe a protocol for a systematic review that will synthesise the qualitative evidence regarding factors influencing the implementation of non-pharmacological interventions (NPIs) for behavioural and psychological symptoms of dementia (BPSD) management in residential aged care homes (RACHs).

PROTOCOL: Effects of guaranteed basic income interventions on poverty-related outcomes in high-income countries: A systematic review.

This is the protocol for a Campbell systematic review. The objectives are as follows: to appraise and synthesize the available quantitative evidence on GBI interventions in high-income countries, for the purpose of comparing the relative effectiveness of specific forms of GBI for alleviating poverty.

Patient experiences of referral practices and primary care physiotherapy for chronic nonspecific low back pain.

Background: Low back pain (LBP) clinical practice guidelines recommend referral for patients with persistent LBP however discordance persists between recommended care and implementation in practice. Understanding patient experiences of referral practices and physiotherapy care could be important for optimizing LBP management in primary care settings.

Purpose: This study explored referral experiences of people with nonspecific LBP in Australian primary care and their knowledge and experience of physiotherapy.

Circulatory disturbance of the cochlear spiral modiolar artery in a type 2 diabetic mouse model.

Objective: This study aimed to identify significant differences in cochlea microvessel size between a diabetic mouse model (db/db) and normal mice using three-dimensional (3D) quantitative analysis.

Methods: Six control heterozygote db/+ as well as 18 male B6/BKS(D)-Lepr/J (db/db) mice aged 14 ( = 9) and 28 ( = 9) weeks were examined. After clearing the cochlea, we reconstructed the 3D volumes of the spiral modiolar artery (SMA) in the cochlea using light-sheet microscopy and analyzed vessel wall thickness, cross-sectional area, short and long diameter, and vessel height.

Nicotinamide adenine dinucleotide and the sirtuins caution: Pro-cancer functions.

This scoping review aims to perform a brief but comprehensive assessment of existing peer-reviewed literature and determine whether raising nicotinamide adenine dinucleotide can prevent or promote tumorigenesis. The examination of extensive peer-reviewed data regarding the synthesis of nicotinamide adenine dinucleotide has been performed with a focus on nuclear dynamics and the deoxyribose nucleic acid repair pathway. Various enzymatic protective functions have been identified from nicotinamide adenine dinucleotide levels, as well as the threat role that is also explored.

Precursor comparisons for the upregulation of nicotinamide adenine dinucleotide. Novel approaches for better aging.

Nicotinamide adenine dinucleotide (NAD) is a coenzyme found in every human cell and regulates a number of systems across multiple cellular compartments and tissue types via an endogenous and exogenous influence. NAD levels are demonstrated to decline with age and therefore measures to counteract the waning of NAD have been devised. A number of NAD precursor candidates such as nicotinamide riboside (NR), nicotinamide mononucleotide (NMN), the reduced form of nicotinamide mononucleotide (NMNH), nicotinic acid (NA) nicotinamide (NAM), and dihydronicotinamide riboside (DNR) increase NAD levels in vitro and in vivo.

Spinopelvic alignment predicts disc calcification, displacement, and Modic changes: Evidence of an evolutionary etiology for clinically-relevant spinal phenotypes.

Lumbar disc-displacement, Modic changes (MCs), and UTE Disc Sign (UDS) on MRI are clinically relevant spinal phenotypes that can lead to sciatica/LBP. Not all degenerated discs result in disc-displacement, MCs and UDS, suggesting varied etiologies. Spinopelvic parameters have been implicated in various spinal disorders.

ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator.

Telomeres constitute the ends of linear chromosomes and together with the shelterin complex form a structure essential for genome maintenance and stability. In addition to the constitutive binding of the shelterin complex, other direct, yet more transient interactions are mediated by the CST complex and HOT1/HMBOX1, while subtelomeric variant repeats are recognized by NR2C/F transcription factors. Recently, the Kruppel-like zinc finger protein ZBTB48/HKR3/TZAP has been described as a novel telomere-associated factor in the vertebrate lineage.

National survey on the practice of radiation therapists in Australia.

Introduction: Radiation therapy (RT), like many allied health professions, has lacked professional practice clarity, which until 2008 had not been comprehensively investigated. This manuscript describes the first phase of a three-phase project investigating the current and future practices of radiation therapists (RTs) in Australia. The aim of phase 1 was to define the practice of RTs in Australia.

HIV/AIDS: A Persistent Health Issue for Women and Children in Mid and Far Western Nepal.

This article reviews the effect of male migration on the spread of HIV infections in mid and far-western Nepal. It explains the link between male mobility and HIV in women and children. Materials were collected by a systematic search of the databases and the websites of national and international agencies.

It doesn't matter what they say, it matters how they behave: Parental influences and changes in body mass among overweight and obese adolescents.

Objective: This study investigated whether the relationships between perceived parental behaviors (dietary behaviors, physical activity, and verbal pressure) and changes in adolescents' body mass index (BMI) were mediated by adolescents' physical activity and dietary behaviors. The associations were tested among overweight and obese adolescents.

Design: Longitudinal data were collected three times, with a 2-month interval between Time 1 (T1) and Time 2 (T2), and a 13-month interval between T2 and Time 3 (T3) in the group of adolescents (N = 100) aged 13-19.

Cross-cultural adaptation process of the "Conversation Analysis Profile for People with Aphasia" to the Portuguese language.

Unlabelled: The Conversation Analysis Profile for People with Aphasia (CAPPA) provides specific information about strengths and weaknesses of the communication between people with aphasia and their family caregiver within a conversational context.

Objective: The aim of this paper was to present the results of the first stages of cross-cultural adaptation of the CAPPA for the European Portuguese language.

Methods: This methodology study describes the translation and back-translation processes, following the recommended steps to that end.

A Web-Based Intervention for Users of Amphetamine-Type Stimulants: 3-Month Outcomes of a Randomized Controlled Trial.

Background: Among illicit drugs, the prevalence of amphetamine-type stimulant (ATS) use is second only to cannabis. Currently, there are no approved pharmacotherapies for ATS problems, but some face-to-face psychotherapies are effective. Web-based interventions have proven to be effective for some substance use problems, but none has specifically targeted ATS users.