Glioblastoma Multiforme in a Patient with Isolated Hemimegalencephaly.

We present an exceptional case of a patient with hemimegalencephaly and secondary intractable epilepsy treated with vagus nerve stimulation (VNS) and subsequent glioblastoma development in the hemimegalencephalic hemisphere 6 years after surgery. VNS (at age 18 years) led to a 60% reduction of intractable seizures. However, symptoms of intracranial hypertension suddenly occurred 6 years after surgery.

Diagnostic value of brain tumor neuroendoscopic biopsy and correlation with open tumor resection.

Background: The risks of stereotactic biopsy are increased not only in tumors located in the vicinity of vascular structures, but also in cystic, intraventricular, and periventricular lesions. The use of neuroendoscopy for cystic, intraventricular, or periventricular brain tumors is particularly advantageous because of the possibility of biopsy and immediate hemostasis under direct vision. Neuroendoscopy provides the possibility of controlling tumor-associated obstructive hydrocephalus by means of endoscopic third ventriculostomy or septostomy.

Histological findings around electrodes in pacemaker and implantable cardioverter-defibrillator patients: comparison of steroid-eluting and non-steroid-eluting electrodes.

Aims: To analyse histological findings surrounding the electrodes in pacemaker/implantable cardioverter-defibrillator (PM/ICD) patients. To compare histology around steroid-eluting and non-steroid ventricular pacing electrodes.

Methods And Results: In autopsied PM/ICD patients histopathological findings around the electrodes were determined.

Minimally invasive treatment of posterior fossa craniopharyngioma by means of navigated endoscopy.

The aim of the paper is to present an unusual case of ectopic posterior fossa craniopharyngioma after repeated surgeries for primary suprasellar tumor. The clinical condition of the patient favored minimally invasive neuroendoscopic surgery. After presurgical planning with the help of neuronavigation system a trajectory from the contralateral side through the cisterna magna was chosen.

Contribution to the V-V interval optimization in patients with cardiac resynchronization therapy.

The present study proposed procedure for predicting an optimal left and right ventricular pacing interval delay (V-V interval). In 16 patients (heart failure, left bundle branch block, biventricular pacing) two methods (A and B) identifying optimal V-V interval were tested. Method A: predicted optimal V-V interval A (POVV-A) = electromechanical delay of the segment paced by left ventricle lead minus electromechanical delay of the segment paced by right ventricle lead.

Exceptional symptomatology of a lipoma beneath the third ventricular floor and successful neuroendoscopic treatment.

The aim of this paper is to present the exceptional case of a lipoma located beneath the floor of the third ventricle in front of right mamillary body manifesting with psychiatric symptoms and treated by navigated neuroendoscopy. A 58-year-old male was referred for neurosurgical treatment because of paroxysmal disturbances of consciousness accompanied by aggressive behaviour. Because electroencephalographic evaluation failed to confirm the epileptic origin of the presenting symptoms, the final psychiatric diagnosis was syndrome of amentia.

Is interhemispheric arachnoid cyst with corpus callosum agenesis related to cavum vergae cyst?

Authors operated on successfully giant interhemispheric arachnoid cyst associated with corpus callosum agenesis. A conclusion was drawn that this cyst was in fact expansive cavum Vergae cyst, taking into consideration the developmental mechanism responsible for the formation of third ventricle dorsal cysts (Fig. 8, Ref.