Follow-up after primary therapy of malignant epithelial ovarian tumors.

Follow-up after finishing the primary therapy has become a routine aimed to an early detection of relapse, decreasing the mortality and improving the quality of patient's life. Main aim of the follow-up is to prolong the life of the patient. No prospective randomized study confirming the scientific character of such aims has been published, so far.

Laboratory testing of hereditary thrombophilia: previous data in the face of verification.

Objective: Mutations in hemocoagulation factors genes are nowadays routinely examined parameters, important in hereditary trombophilia determination. We have complexly evaluated laboratory data from the 211 unselected patients with venous thrombosis, and compared with the former studies in the same Slovakian population.

Results: The Factor V Leiden mutation (FVL) was found in 43 of 211 patients (20.

Prognostic factors in endometrial carcinoma.

Endometrial carcinoma is the most common malignancy of the female genital tract in industrialized countries, and occurs predominantly after the menopause. Although most endometrial carcinomas are detected at low stage, there is still a significant mortality from the disease. In postmenopausal women, prolonged life expectancy, changes in reproductive behavior and prevalence of overweight and obesity, as well as hormone replacement therapy use, may partially account for the observed increases of incidence rates in some countries.

Prognostic factors in women 45 years of age or younger with endometrial cancer.

The purpose of this study was to conduct a clinical and pathologic review of endometrial cancers diagnosed in women aged younger than 45 years to better identify the prognostic factors for this subgroup of women. We retrospectively evaluated the clinical history, treatment, and follow-up of patients with histologically confirmed endometrial cancer treated in Faculty Hospital Nitra, Slovakia from 1993 to 2003. Data were abstracted regarding tumor histology, grade, age, parity, stage, diabetes, use of oral contraceptives, body mass index (BMI), and survival.

Elevation of serum CA 125 and D-dimer levels associated with rupture of ovarian endometrioma.

Background: Patients with endometriosis rarely have a serum CA 125 concentration >100 IU/mL. A raised plasma level of D-dimer indicates active fibrinolysis, either secondary to clot formation or primarily activated. This condition is seldom diagnosed in patients with endometriosis.

Combined parasacral, vaginal and endorectal approach in surgical treatment of giant rectocele.

Authors operated on their Surgical departement 67 years old women with incomplete evacuation, and digital support during defecation, giant rectocele and massive vaginal vault prolaps. Authors realized cinedefecography and detected giant rectocele, depth was 8 cm, anorectal angle was 120 degrees. They stated Resting pressure 40 cm H2O, and Maximum squeeze pressure 50cm H2O by anorectal manometry.

Endometrial adenocarcinoma presenting with an osseous metastasis.

Background: Gynecologic cancers metastatic to bone are rare. Endometrial carcinoma usually presents with vaginal bleeding.

Case Report: A 67-year-old woman presented with pain, erythema and swelling of the right foot and no history of postmenopausal bleeding.

Peritoneal cytology in endometrial cancer.

The results as well as prognostic interpretation of peritoneal washing cytology in endometrial cancer cases is still controversial. The incidence rate of positive cytology varies widely and the clinical significance of the positive results, especially in patients with early stage of endometrial cancer remains also controversial. Prognostic significance of malignant peritoneal cytology in endometrial cancer patients in comparison with those with ovarian cancer has been less well defined.