2,613 results match your criteria: "Faculté de Médicine et des Sciences Biomédicales de l'Université de Yaoundé I[Affiliation]"

The insertion/deletion (I/D) polymorphism in , the gene encoding the angiotensin-converting enzyme (ACE), has been suggested as a genetic variation that can influence exercise performance and risk of injury in elite athletes. The I allele has been associated with enhanced endurance performance and with reduced inflammation, while the D allele has been associated with improved performance in strength and power activities. However, the role of this genetic variant in the incidence of non-contact injury is underexplored.

View Article and Find Full Text PDF

The fluke Clinostomum complanatum, a parasite of piscivorous birds, but also reptiles and rarely mammals, has established several foci in the western Palaearctic regions. Previous studies pointed out the complicated taxonomy of the genus, but broader population genetic analysis of C. complanatum has not yet been carried out.

View Article and Find Full Text PDF

The 2025 Motile Active Matter Roadmap.

J Phys Condens Matter

January 2025

Biozentrum, University of Basel, Spitalstrasse 41, Basel, Basel-Stadt, 4056, SWITZERLAND.

Activity and autonomous motion are fundamental aspects of many living and engineering systems. Here, the scale of biological agents covers a wide range, from nanomotors, cytoskeleton, and cells, to insects, fish, birds, and people. Inspired by biological active systems, various types of autonomous synthetic nano- and micromachines have been designed, which provide the basis for multifunctional, highly responsive, intelligent active materials.

View Article and Find Full Text PDF

Animal translocations provide striking examples of the human footprint on biodiversity. Combining continental-wide genomic and DNA-barcoding analyses, we reconstructed the historical biogeography of the Asian black-spined toad (Duttaphrynus melanostictus), a toxic commensal amphibian that currently threatens two biodiversity hotspots through biological invasions (Wallacea and Madagascar). The results emphasize a complex diversification shaped by speciation and mitochondrial introgression that comprises two distinct species.

View Article and Find Full Text PDF

Genetic Diversity and Relationships Among Tunisian Wild and Cultivated L. Species.

Plants (Basel)

December 2024

LR99ES12, Laboratoire de Génétique Moléculaire, Immunologie et Biotechnologie, Faculté des Sciences de Tunis, Université de Tunis El Manar, Tunis 2092, Tunisia.

Assessing and determining genetic diversity in rose species is a crucial step for conservation efforts, the establishment of a core collection, and the development of new varieties. This study represents the first investigation of genetic diversity among various rose species at different ploidy levels in Tunisia, with the aim of elucidating the genetic structure of the genus. It encompasses both spontaneous and cultivated accessions, featuring local and introduced species recognized for their adaptability, ornamental value, and fragrance.

View Article and Find Full Text PDF

This study investigates the synthesis of corn starch nanocrystals (SNCs) via sulfuric acid hydrolysis. Esterification of oleic acid (OA) with SNCs was carried out using Maghnite-H as a catalyst, a non-polluting, eco-friendly proton-exchanged montmorillonite-based green catalyst suitable for various chemical processes. Optimization of synthesis parameters, including reaction temperature, duration, and catalyst quantity, was conducted using response surface methodology (RSM) with a central composite design incorporating three factors and three levels.

View Article and Find Full Text PDF

Introduction: the epidemiological profile of oral diseases is characterised by disparities between specific groups. The purpose of this study was to assess oral health status of Baka Pygmies in Dimako, Cameroon.

Methods: we conducted a cross-sectional study from January 1 to June 14, 2021 in the Baka camps in Dimako.

View Article and Find Full Text PDF

Photodissociation of the CH2Cl radical: A high-level ab initio study.

J Chem Phys

December 2024

Instituto de Física Fundamental, Consejo Superior de Investigaciones Científicas, Serrano 123, 28006 Madrid, Spain.

Photodissociation of the CH2Cl radical is investigated by using high-level multireference configuration interaction ab initio methods, including the spin-orbit coupling. All possible fragmentation pathways, namely, CH2Cl + hν → CH2 + Cl, HCCl + H, and CCl + H2, have been analyzed. The potential-energy curves of the ground and several excited electronic states along the corresponding dissociating bond distance of each pathway have been calculated.

View Article and Find Full Text PDF

Morphological . molecular identification of trematode species infecting the edible cockle across Europe.

Int J Parasitol Parasites Wildl

December 2024

Univ. Bordeaux, CNRS, Bordeaux INP, EPOC, UMR, 5805, Station Marine d'Arcachon, Arcachon, France.

Identifying marine trematode parasites in host tissue can be complicated when there is limited morphological differentiation between species infecting the same host species. This poses a challenge for regular surveys of the parasite communities in species of socio-economic and ecological importance. Our study focused on identifying digenean trematode species infecting the marine bivalve across Europe by comparing morphological and molecular species identification methods.

View Article and Find Full Text PDF

Tuberculosis in adult migrants in Europe: a TBnet consensus statement.

Eur Respir J

December 2024

Clinical Infectious Diseases, Research Center Borstel, Leibniz Lung Center, Borstel, Germany.

Introduction: Global migration has increased in recent decades due to war, conflict, persecutions, and natural disasters, but also secondary to increased opportunities related to work or study. Migrants' risk of tuberculosis (TB) differs by reasons for migration, socioeconomic status, mode of travel and TB risk in transit, TB incidence and healthcare provision in country of origin. Despite advances in TB care for migrants and new treatment strategies, decisions for the management of migrants at risk of TB often rely on expert opinions, rather than clinical evidence.

View Article and Find Full Text PDF

Intrinsic and environmental drivers of pairwise cohesion in wild Canis social groups.

Ecology

January 2025

Wildlife Research and Monitoring Section, Ministry of Natural Resources and Forestry, Peterborough, Ontario, Canada.

Animals within social groups respond to costs and benefits of sociality by adjusting the proportion of time they spend in close proximity to other individuals in the group (cohesion). Variation in cohesion between individuals, in turn, shapes important group-level processes such as subgroup formation and fission-fusion dynamics. Although critical to animal sociality, a comprehensive understanding of the factors influencing cohesion remains a gap in our knowledge of cooperative behavior in animals.

View Article and Find Full Text PDF

Potential impact of tide-regulation barriers on the formation of methylmercury in the Venice Lagoon (Italy).

J Hazard Mater

December 2024

Department F.-A. Forel for Environmental and Aquatic Sciences, and Institute for Environmental Sciences, University of Geneva, Geneva, Switzerland. Electronic address:

Methylmercury (MeHg), a neurotoxic pollutant, is formed mainly under anaerobiosis. The "Modulo Sperimentale Elettromeccanico" (MOSE), built to temporarily close the Venice Lagoon and protect the city from flooding, induces changes in the hydrological regime, reducing water circulation and decreasing in the dissolved oxygen concentrations of the lagoon. Our study shows the potential changes in sediment and overlying water physico-chemistry in a simulated MOSE closing-event by incubating sediment cores for 48 h in the laboratory and deploying benthic chambers.

View Article and Find Full Text PDF

Genomic perspective on the bacillus causing paratyphoid B fever.

Nat Commun

December 2024

Institut Pasteur, Université Paris Cité, Unité des Bactéries pathogènes entériques, Paris, F-75015, France.

Paratyphoid B fever (PTB) is caused by an invasive lineage (phylogroup 1, PG1) of Salmonella enterica serotype Paratyphi B (SPB). However, little was known about the global population structure, geographic distribution, and evolution of this pathogen. Here, we report a whole-genome analysis of 568 historical and contemporary SPB PG1 isolates, obtained globally, between 1898 and 2021.

View Article and Find Full Text PDF

Background: Trachoma programs use the indicator trachomatous inflammation--follicular (TF) to monitor indication for and response to treatment for trachoma at the district level. Alternative indicators, including serologic markers, are increasingly being evaluated for trachoma surveillance. We evaluated seroprevalence of IgG antibodies to the Pgp3 antigen in two districts in Maradi, Niger thought to have low TF prevalence.

View Article and Find Full Text PDF
Article Synopsis
  • The CMS experiment conducted a search for charge-parity violation in decays using proton-proton collision data from 2018, analyzing around 10 billion events with b hadrons decaying into charm hadrons.
  • The flavor of the neutral D meson was determined through the charge of pions in the reconstructed decays, and an asymmetry measurement in the decays was reported, taking into account various uncertainties.
  • This research marks the first asymmetry measurement by the CMS in the charm sector and the first to use a fully hadronic final state in such analyses.
View Article and Find Full Text PDF

Frogs of the genus Platypelis are known to have their center of species richness in the mountain massifs of northern Madagascar. We here formally describe a new species of Platypelis from this region. Platypelis saikamavo sp.

View Article and Find Full Text PDF

Patient-Relevant Digital-Motor Outcomes for Clinical Trials in Hereditary Spastic Paraplegia Type 7: A Multicenter PROSPAX Study.

Neurology

December 2024

Division Translational Genomics of Neurodegenerative Diseases (L.B., A.T., D.M., M.S.), Hertie-Institute for Clinical Brain Research and Center for Neurology, and German Center for Neurodegenerative Diseases (DZNE) (L.B., A.T., D.M., K.D.-J., M.S., R.S.), University of Tübingen; Section Computational Sensomotorics (J.S., W.I.), Hertie Institute for Clinical Brain Research; Centre for Integrative Neuroscience (CIN) (J.S., W.I.); Department of Neurodegenerative Diseases (C.K.), Hertie-Institute for Clinical Brain Research and Center for Neurology, University of Tübingen; Center for Neurology and Hertie Institute for Clinical Brain Research (K.D.-J., R.S.), University Hospital Tübingen, Germany; Molecular Medicine (I.R., S.S.), IRCCS Fondazione Stella Maris, Pisa, Italy; Koç University (N.A.B.), Translational Medicine Research Center, KUTTAM-NDAL, Istanbul, Turkey; Sorbonne Université (G.C.), Paris Brain Institute, INSERM, CNRS, APHP, France; Department of Neurology and Center for Translational Neuro- and Behavioral Sciences (D.T.), University Hospital Essen, University of Duisburg-Essen, Germany; Groupe de recherche interdisciplinaire sur les maladies neuromusculaires (GRIMN) (C.G.), Centre intégré universitaire de santé et de services sociaux du Saguenay-Lac-St-Jean; Centre de recherche du Centre intégré universitaire de santé et de services sociaux du Saguenay-Lac-St-Jean (C.G.); Faculté de médecine et des sciences de la santé (C.G.), Université de Sherbrooke, Québec, Canada; Department of Neurology (B.P.C.v.d.W.), Radboud University Medical Center, Nijmegen, the Netherlands; and Division of Neurodegenerative Diseases (R.S.), Department of Neurology, Heidelberg University Hospital, Germany.

Article Synopsis
  • The study focuses on identifying valid digital-motor outcome measures using wearable sensors for spastic paraplegia type 7 (SPG7), a common spastic ataxia, aiming to reflect health aspects relevant to patients in early disease stages and suitable for multicenter trials.
  • Gait analysis was performed in 65 SPG7 patients and 50 healthy controls, where 18 out of 30 analyzed gait measures effectively discriminated between the two groups, even in mild disease stages.
  • Key findings highlighted that specific spatiotemporal variability measures strongly correlate with functional mobility and overall disease severity, indicating their potential as sensitive outcome measures for future trials.
View Article and Find Full Text PDF

Background: Among inherited cardiomyopathies involving the left ventricle, whether dilated or not, certain genotypes carry a well-established arrhythmic risk, notably manifested as sustained monomorphic ventricular tachycardia (SMVT). Nonetheless, the precise localization and electrophysiological profile of this substrate remain undisclosed across different genotypes.

Methods: Patients diagnosed with cardiomyopathy and left ventricle involvement due to high-risk genetic variants and SMVT treated by electrophysiological study were recruited from 18 European/US centers.

View Article and Find Full Text PDF

In Vitro Antimicrobial Activity of Volatile Compounds from the Lichen (L.) Zopf. Against Multidrug-Resistant Bacteria and Fish Pathogens.

Microorganisms

November 2024

Interdisciplinary Centre of Marine and Environmental Research (CIIMAR/CIMAR), University of Porto, Terminal de Cruzeiros do Porto de Leixões, 4450-208 Matosinhos, Portugal.

Lichens are symbiotic organisms with unique secondary metabolism. Various metabolites from lichens have shown antimicrobial activity. Nevertheless, very few studies have investigated the antimicrobial potential of the volatile compounds they produce.

View Article and Find Full Text PDF

Porous solids for energy applications.

J Chem Phys

November 2024

Phases to Flow Laboratory, Chemical and Biological Engineering Department, Colorado School of Mines, Golden, Colorado 80401, USA.

View Article and Find Full Text PDF

Objective: Few studies have evaluated the efficacy of antiseizure medications (ASMs) according to the etiology of neonatal acute provoked seizures. We aimed to investigate the response to ASMs in term/near term neonates with acute arterial ischemic stroke (AIS), as well as the type of seizure at presentation and the monitoring approach.

Methods: We retrospectively evaluated neonates from 15 European level IV neonatal intensive care units who presented with seizures due to AIS and were monitored by continuous electroencephalography (cEEG) and/or amplitude-integrated EEG (aEEG) in whom actual recordings, timing, doses, and response to ASMs were available for review.

View Article and Find Full Text PDF

Chronic myelomonocytic leukemia (CMML) is a severe myeloid malignancy affecting the elderly, for which therapeutic options are limited. DNA hypomethylating agents (HMAs) provide transient responses, failing to eradicate the malignant clone. Hematopoietic stem cell (HSC) aging involves heterochromatin reorganization, evidenced by alterations in histone marks H3K9me2 and H3K9me3.

View Article and Find Full Text PDF

2025 Roadmap on 3D Nano-magnetism.

J Phys Condens Matter

November 2024

Institute of Applied Physics, Vienna University of Technology, Wiedner Hauptstr. 8-10/134, Wien, 1040, AUSTRIA.

The transition from planar (2D) to three-dimensional (3D) magnetic nanostructures represents a significant advancement in both fundamental research and practical applications, offering vast potential for next-generation technologies like ultrahigh-density storage, memory, logic, and neuromorphic computing. Despite being a relatively new field, the emergence of 3D nanomagnetism presents numerous opportunities for innovation, prompting the creation of a comprehensive roadmap by leading international researchers. This roadmap aims to facilitate collaboration and interdisciplinary dialogue to address challenges in materials science, physics, engineering, and computing.

View Article and Find Full Text PDF

The first search for soft unclustered energy patterns (SUEPs) is performed using an integrated luminosity of 138  fb^{-1} of proton-proton collision data at sqrt[s]=13  TeV, collected in 2016-2018 by the CMS detector at the LHC. Such SUEPs are predicted by hidden valley models with a new, confining force with a large 't Hooft coupling. In events with boosted topologies, selected by high-threshold hadronic triggers, the multiplicity and sphericity of clustered tracks are used to reject the background from standard model quantum chromodynamics.

View Article and Find Full Text PDF