1,314 results match your criteria: "FOCH Hospital[Affiliation]"
Impact of facial nerve resection in parotid cancer abutting the facial nerve without preoperative paralysis: A multicentric propensity score-based analysis.
Eur J Surg Oncol
October 2024
Université Paris Cité, ENT - Head and Neck Surgery Department, AP-HP, Hôpital Lariboisière, INSERM U1141, F-75010, Paris, France.
Objectives: The management of the facial nerve (FN) is a major issue in parotid cancer, especially when there is no preoperative facial palsy and FN invasion is discovered intraoperatively. The aim of this study was to assess the impact of FN resection in patients with parotid cancer abutting the FN, without pretreatment facial palsy, using a propensity score matching.
Materials And Methods: Data from all patients treated between 2009 and 2020 for a primary parotid cancer abutting or invading the FN but without pretreatment facial palsy were extracted from the national multicentric REFCOR database.
Surgical Treatments of Pediatric Bilateral Vocal Fold Paralysis: A Systematic Review.
J Otolaryngol Head Neck Surg
October 2024
Research Committee of the Young Otolaryngologists of the International Federation of Otorhinolaryngological Societies, Paris, France.
Objective: To review the current literature about surgical treatments of pediatric bilateral vocal fold paralysis (PBVFP).
Methods: A systematic review of the current literature in PubMed, Scopus, and Cochrane Library regarding etiologies and management of PBVFP was performed until November 2023 according to PRISMA statements. Quality assessment was assessed with Methodological Index for Non-Randomized Studies (MINORS) tool.
Effectiveness of temocillin in treatment of non-urinary tract infections caused by ESBL-producing Enterobacterales and risk factors for failure.
JAC Antimicrob Resist
October 2024
Infectious Disease Department, Raymond Poincaré Hospital, APHP, Garches, France.
Objectives: To describe the real-life use of temocillin for non-urinary tract infections, to assess its effectiveness in infections caused by ESBL-producing Enterobacterales, and to identify risk factors for treatment failure.
Method: Retrospective multicentric study in 14 tertiary care hospitals, including all patients who received at least one dose of temocillin for ESBL infections from 1 January 2016 to 31 December 2021 for non-urinary tract infections. Failure was a composite criterion defined within 28 day follow-up by persistence or reappearance of signs of infection, and/or switch to suppressive antibiotic treatment and/or death from infection.
Air Pollution Exposure at Time of Lung Transplant and Survival: Can We Do Better?
JAMA Netw Open
October 2024
Division of Respirology, Department of Medicine, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Competing and Noncompeting Risk Models for Predicting Kidney Allograft Failure.
J Am Soc Nephrol
October 2024
Université de Paris Cité, INSERM, PARCC, Paris Institute for Transplantation and Organ Regeneration, F-75015 Paris, France.
Article Synopsis
- The study investigates how competing risks, like allograft failure and death with a functioning graft, affect the performance of prognostic models used for kidney transplant recipients.
- The research involves 11,046 kidney transplant recipients across 10 countries, developing models using various regression techniques to predict long-term graft failure while carefully evaluating their accuracy and reliability.
- Results indicate that both standard Cox models and competing risk models provide similar predictions for graft failure, with high concordance indices, confirming their usefulness in clinical settings.
Endovascular treatment versus medical management for basilar artery occlusion with low-to-moderate symptoms (National Institutes of Health Stroke Scale < 10).
Eur Stroke J
October 2024
Department of Medicine, Division of Neurology, The Ottawa Hospital, Ottawa Hospital Research Institute and University of Ottawa, Ottawa, Canada.
Background: Patients with acute basilar artery occlusion (BAO) and low-to-moderate symptoms (National Institutes of Health Stroke Scale [NIHSS] < 10) are poorly represented in thrombectomy trials. Our objective is to compare thrombectomy and best medical management (BMT) in this population.
Methods: We compared data of all consecutive patients presenting with an initial NIHSS < 10 and acute symptomatic BAO included in two registries.
Incidence and clinical impact of aspiration during cesarean delivery: A multi-center retrospective study: Addressing the hidden risk: Aspiration during cesarean delivery.
Anaesth Crit Care Pain Med
December 2024
Department of Anaesthesia and Pain Medicine, Foch Hospital, Suresnes, France; University of Versailles Saint Quentin, France.
Association between empty nose syndrome and laryngopharyngeal reflux disease: a preliminary cohort study.
Eur Arch Otorhinolaryngol
October 2024
Faculty of Medicine and Surgery, University of Enna Kore, Enna, 94100, Italy.
Article Synopsis
- * A total of 41 ENS patients were assessed alongside control groups, revealing that ENS patients exhibited significantly higher LPRD symptoms and severity, as well as a notable prevalence of depression.
- * The results indicated that LPRD symptoms were much more common in ENS patients than in controls, suggesting a strong association that warrants further research using objective methods to confirm these findings.
Changes in practices concerning urethral stricture surgery: Analysis of French data for the period 2013-2022.
Fr J Urol
October 2024
Urology Department, Foch Hospital, Suresnes, France. Electronic address:
Article Synopsis
- Urethral stricture has a prevalence of about 0.9%, and while endoscopic treatments have been the primary approach, their effectiveness has led to a shift towards urethroplasty as the preferred treatment from 2013 to 2022.
- Data from the Scansanté platform shows that while endoscopic procedures remain common, urethroplasties have increased noticeably since 2019, rising from 1,100 to 1,600 cases from 2020 to 2022.
- Despite urethrotomies still outnumbering urethroplasties by a large margin, the gap is narrowing, and urethroplasty, particularly with augmentation techniques, is now recognized as
Functional outcomes after supra-pubic phalloplasty.
J Plast Reconstr Aesthet Surg
December 2024
Urology Department, Hôpital Lyon Sud, Hospices Civils de Lyon, Lyon, France; Université Claude Bernard Lyon 1, Lyon, France. Electronic address:
Article Synopsis
- - The study evaluates the outcomes of supra-pubic phalloplasty (SPP) in terms of sexuality, urinary function, and overall patient satisfaction, focusing on data collected from patients treated between 2007 and 2018.
- - A total of 77 patients participated, with 33 responding to questionnaires; results indicated high satisfaction levels, a mean neophallus length of 15.3 cm, and favorable sexual and urinary function outcomes.
- - The findings suggest that pre-expanded SPP is an effective technique, providing significant improvements in appearance and function, along with a high rate of satisfaction regarding the phalloplasty experience.
Tensions between end-of-life care and organ donation in controlled donation after circulatory death: ICU healthcare professionals experiences.
BMC Med Ethics
October 2024
Famiréa Research Group, Medical Intensive Care Unit, APHP, Hospital Saint-Louis, Paris, France.
Article Synopsis
- The study investigates the experiences of ICU healthcare professionals regarding controlled donation after circulatory death (cDCD), amid ethical concerns between end-of-life care and organ donation.
- Conducted in 32 ICUs in France, the study surveyed 206 physicians and nurses after the deaths of patients considered potential cDCD donors, measuring their anxiety levels and feelings of tension related to the donation process.
- Results show that cDCD does not significantly increase anxiety for healthcare professionals compared to regular end-of-life situations, with a general positive perception of cDCD among them, suggesting a need for better support in balancing life support decisions and organ donation.
Inter-rater Reliability of the Reflux Sign Assessment-10 (RSA-10).
J Voice
October 2024
Haute Ecole Condorcet, Division of Speech Therapy, Saint-Ghislain, Belgium.
Objective: To evaluate the inter-rater reliability and internal consistency of the Reflux Sign Assessment-10 (RSA-10) among otolaryngologists and speech therapists with various experiences.
Methods: Six experts (2 otolaryngologists, 2 speech-therapists, and 2 speech-therapist students) rated 300 clinical images of oral, laryngeal, and pharyngeal signs from patients with laryngopharyngeal reflux disease diagnosis at the 24-hour hypopharyngeal-esophageal multichannel intraluminal impedance-pH monitoring. Inter-rater reliability and internal consistency were evaluated with Intraclass Correlation (ICC) and Cronbach-α.
In Reference to Treatment Outcomes of Intralesional Steroid Injection for Refractory Vocal Process Granuloma.
Clin Otolaryngol
January 2025
Department of Otolaryngoly-Head Neck Surgery, Foch Hospital, University of Paris Saclay, Paris, France.
The genomic and transcriptomic landscape of metastastic urothelial cancer.
Nat Commun
October 2024
Department of Genetics, Institut Curie, 75005, Paris, France.
Article Synopsis
- Metastatic urothelial carcinoma (mUC) is a dangerous cancer with few treatment options, and its genetic makeup is not fully understood unlike non-metastatic urothelial carcinoma (UC).
- A study analyzing genetic data from 111 mUC biopsies found that common genetic changes are similar to those seen in primary UC and highlighted mutational signatures related to APOBEC, platinum sensitivity, and homologous recombination deficiency.
- The research revealed that a significant portion of mUC patients have potential therapeutic targets, with the most common being FGFR3, ERBB2, TSC1, and PIK3CA, and noted that certain genes like NECTIN4 and TACSTD2 are consistently highly expressed across different
Accuracy of ChatGPT responses on tracheotomy for patient education.
Eur Arch Otorhinolaryngol
November 2024
Department of Surgery, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium.
Objective: To investigate the accuracy of information provided by ChatGPT-4o to patients about tracheotomy.
Methods: Twenty common questions of patients about tracheotomy were presented to ChatGPT-4o twice (7-day intervals). The accuracy, clarity, relevance, completeness, referencing, and usefulness of responses were assessed by a board-certified otolaryngologist and a board-certified intensive care unit practitioner with the Quality Analysis of Medical Artificial Intelligence (QAMAI) tool.
Hearing Loss, Hearing Aids, and Cognition.
JAMA Netw Open
October 2024
Université Paris Cité, Inserm, U970, Paris Cardiovascular Research Center, Integrative Epidemiology of Cardiovascular Disease, Paris, France.
Importance: Most observational studies examining the association between hearing loss (HL) and cognitive impairment used subjective measures of hearing and addressed only one dimension of cognition, and very few investigated the potential benefit of hearing aids (HAs).
Objective: To evaluate objectively measured HL and several dimensions of cognition and estimate the association with HA use.
Design, Setting, And Participants: A cross-sectional analysis of the CONSTANCES cohort study, which recruited participants from January 1, 2012, to December 31, 2020, was conducted.
Incontinentia pigmenti underlies thymic dysplasia, autoantibodies to type I IFNs, and viral diseases.
J Exp Med
November 2024
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Inserm U1163, Necker Hospital for Sick Children, Paris, France.
Article Synopsis
- * A study examined 131 female patients with X-linked dominant incontinentia pigmenti (IP), finding that 36% produced autoantibodies against IFN-α and/or IFN-ω, significantly higher than age-matched controls.
- * The presence of these autoantibodies is linked to an abnormally small thymus and predisposes patients to life-threatening viral infections, while those without these autoantibodies do not face the same risk.
Effectiveness of Changing Drug Classes in Patients With Refractory Laryngopharyngeal Reflux Disease.
Otolaryngol Head Neck Surg
September 2024
Department of Anatomy, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium.
Objective: To investigate the effectiveness of drug class changes in patients with refractory laryngopharyngeal reflux disease (LPRD).
Study Design: Retrospective case series with prospective data.
Setting: Multicenter study.
Surgical, Functional, and oncological outcomes of transoral robotic surgery for cT1-T3 supraglottic laryngeal Cancers: A systematic review.
Oral Oncol
December 2024
Department of Surgery, Faculty of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium; Department of Otolaryngology, Elsan Hospital, Poitiers, France; Department of Otolaryngology-Head Neck Surgery, Foch Hospital, UFR Simone Veil, University Versailles Saint-Quentin-en Yvelines (University Paris Saclay), Paris, France; Department of Otorhinolaryngology and Head and Neck Surgery, CHU Saint-Pierre, Brussels, Belgium. Electronic address:
Background: This systematic review investigated the surgical, functional, and oncological outcomes of transoral robotic supraglottic laryngectomy (TORS-SGL) for cT1-T3 laryngeal squamous cell carcinoma (LSCC).
Methods: Two investigators conducted an updated PubMed, Scopus, and Cochrane Library systematic review for studies investigating the surgical, functional, and oncological outcomes of TORS-SGL using the PRISMA statements. The bias analysis was conducted with the MINORS.
Acceptability determinants of a proposal to reduce antiretroviral treatment to an oral two-drug regimen among patients living with HIV and physicians in France.
PLoS One
September 2024
URC-ECO, Hotel-Dieu Hospital, AP-HP, Paris, France.
An oral two-drug regimen (O2DR) in the form of a once-a-day single tablet is now recommended for treatment switching and treatment initiation for HIV. In clinical care, the process of treatment change refers to adaptation issues, both individual and within the care relationship. The study aim is to present the determinants involved in the acceptability of switching to O2DR in the PROBI (Patient-Reported Outcomes BItherapy) qualitative study.
View Article and Find Full Text PDFChatGPT and trainee performances in the management of maxillofacial patients.
J Stomatol Oral Maxillofac Surg
September 2024
Department of Stomatology, Oral & Maxillofacial Surgery, CHU Saint Pierre, Brussels, Belgium; Faculty of Medicine, Department of Human Anatomy and Experimental Oncology UMONS, Mons, Belgium.
Introduction: ChatGPT is an artificial intelligence based large language model with the ability to generate human-like response to text input, its performance has already been the subject of several studies in different fields. The aim of this study was to evaluate the performance of ChatGPT in the management of maxillofacial clinical cases.
Materials And Methods: A total of 38 clinical cases consulting at the Stomatology-Maxillofacial Surgery Department were prospectively recruited and presented to ChatGPT, which was interrogated for diagnosis, differential diagnosis, management and treatment.
Chronic Cough Related to Thyroid Cartilage Superior Cornu Abnormality.
Ear Nose Throat J
September 2024
Department of Physiology, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium.
Article Synopsis
- - Chronic cough is a frequent issue seen in patients seeking help from otolaryngology specialists, but it can sometimes be linked to rare anatomical problems.
- - A case study is presented about a 64-year-old woman whose chronic cough was caused by a curved superior cornu of the thyroid cartilage, irritating a nearby nerve.
- - After surgically removing the abnormal cartilage, the patient's cough improved and did not return after 9 months, suggesting that examining the laryngeal structure might uncover treatable causes of chronic cough.
AI in obstetrics: Evaluating residents' capabilities and interaction strategies with ChatGPT.
Eur J Obstet Gynecol Reprod Biol
November 2024
Department of Anaesthesiology, Hôpital de la Croix-Rousse, Hospices civils de Lyon, Lyon, France; RESHAPE UMR 1290 INSERM, Université Lyon 1, Lyon, France.
Article Synopsis
- - This study investigated how obstetrics residents interact with ChatGPT while evaluating their knowledge on acute hepatic steatosis of pregnancy and their self-reported IT and AI skills.
- - Results showed that although residents had moderate IT skills, they had low AI proficiency, leading to only 21% accurate responses when querying ChatGPT, primarily due to misunderstanding medical terms.
- - The findings suggest the need for structured AI literacy programs in medical education, emphasizing effective use of AI to improve patient care and prevent misinformation in clinical settings.
Accuracy and consistency of ChatGPT-3.5 and - 4 in providing differential diagnoses in oral and maxillofacial diseases: a comparative diagnostic performance analysis.
Clin Oral Investig
September 2024
Dental School, University Brasil, Fernandópolis, Brazil.
Objective: To investigate the performance of ChatGPT in the differential diagnosis of oral and maxillofacial diseases.
Methods: Thirty-seven oral and maxillofacial lesions findings were presented to ChatGPT-3.5 and - 4, 18 dental surgeons trained in oral medicine/pathology (OMP), 23 general dental surgeons (DDS), and 16 dental students (DS) for differential diagnosis.
Malignant salivary gland tumors of the tongue: A multicenter REFCOR study.
Int J Cancer
January 2025
Otolaryngology, Head and Neck Surgery Department, University Cancer Institute Toulouse and Toulouse University Hospital, Larrey Hospital, Toulouse, France.
Article Synopsis
- Salivary carcinomas of minor salivary glands, particularly in the tongue, are rare tumors that may require surgery and/or (chemo-)radiotherapy for treatment.
- A study involving 103 patients diagnosed between 2009 and 2018 found that the most common types were adenoid cystic and mucoepidermoid carcinomas, with surgery being the primary treatment for most cases.
- Results indicated that 5-year overall survival was 84.7%, while event-free survival was lower at 38.6%; nonsurgical treatment, alcohol use, and tumor location negatively impacted event-free survival, while nodal positivity was a key factor affecting overall survival.