4,349 results match your criteria: "FEDERAL UNIVERSITY OF PERNAMBUCO[Affiliation]"

This study investigated the prevalence of white-coat hypertension (WCH) among individuals with office isolated systolic hypertension (ISH), isolated diastolic hypertension (IDH), and systolic-diastolic hypertension (SDH). We evaluated 9122 individuals [57.0 ± 14.

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Ocotea is an important genus of Lauraceae plant family that comprises over 400 species, many of which pose challenges in taxonomic differentiation due to their complex botanical characteristics. Chemosystematics, and more recently, chemophenetics, have emerged as valuable tools to address these challenges based on their natural products (NPs) composition. O.

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  • Otoliths play a crucial role in marine biology, aiding in studies related to fish metabolism, age, growth, and stock identification for sustainable management.
  • The research utilizes micro-computed tomography to analyze otolith density variations but notes a lack of methodologies for comparative studies, leading to the application of the Ball Mapper technique in this analysis.
  • This study emphasizes reducing computational costs through probabilistic sampling, validating sample representativeness, and uncovering significant correlations between age and network properties, showcasing the effectiveness of the Ball Mapper in processing tomographic images.
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Age-related macular degeneration (AMD), a complex neurodegenerative disease, is a leading cause of visual impairment worldwide with a strong genetic component. Genetic studies have identified several loci, but few causal genes with functional characterization. Here we highlight multiple lines of evidence which show a causal role in AMD for SLC16A8, which encodes MCT3, a retinal pigment epithelium (RPE) specific lactate transporter.

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Background: A-mode ultrasound (US) is a potential method for directly measuring muscle thickness in patients with cancer, but its utility remains underexplored. We aimed to evaluate the feasibility of using A-mode US to assess muscle thickness, compare it with computed tomography (CT)-derived results, and assess its ability to diagnose sarcopenia.

Methods: A cross-sectional analysis was conducted with hospitalized patients with cancer.

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This study characterized polycyclic aromatic hydrocarbons (PAHs) in oil pellets stranded at Fernando de Noronha Archipelago, equatorial Atlantic. It also characterized PAHs dissolved/dispersed in seawater (i.e.

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This study assessed the SARS-CoV-2 surrogate bacteriophage φ6 cross-contamination between high-density polyethylene or polyvinyl chloride gloves and fruits (tomato and cucumber) using different inoculum levels (6.0 and 4.0 log PFU/sample).

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The COVID-19 pandemic has raised concerns beyond the viral infection itself. Bacterial co-infections, particularly those involving Acinetobacter baumannii, have become a significant worry in critically ill COVID-19 patients. A.

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Study evaluated the influence of ozonization (O) time combined with pulsed electric fields (PEF) on the modification of bean starch structure. O₃ was used at a concentration of 0.045 g/L for 60 min (Oz1) and 120 min (Oz2) both individually and in combination with 30 kV/cm (P30).

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Background: Hypertension is the most prevalent cardiovascular risk factor, with several detrimental effects on the cardiovascular system. Contrasting results have been reported so far on its prognostic role in patients admitted for ST-segment elevation myocardial infarction (STEMI). Therefore, we investigated the impact of hypertension on short-term mortality in a large multicenter contemporary registry of STEMI patients, including patients treated during COVID-19 pandemic.

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This study was conducted with the objective of evaluating the impact of replacing inorganic mineral sources (IM) with amino acid complexed minerals (AACM) in laying hens' diets on performance, egg quality, bone, and intestinal health. The effects of 4 different diets with varying levels of AACM substitution were evaluated on 400 Lohmann White hens aged 78-98 weeks. The control diet contained only IM sources at levels of 60, 60, 7, 40, 0.

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Plasmonic nanostructures have emerged as indispensable components in the construction of high-performance gas sensors, playing a pivotal role across diverse applications, including industrial safety, medical diagnostics, and environmental monitoring. This review paper critically examines seminal research that underscores the remarkable efficacy of plasmonic materials in achieving superior attributes such as heightened sensitivity, selectivity, and rapid response times in gas detection. Offering a synthesis of pivotal studies, this review aims to furnish a comprehensive discourse on the contemporary advancements within the burgeoning domain of plasmonic gas sensing.

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  • Visceral leishmaniasis (VL) is a tropical disease caused by a parasite, influenced by environmental and genetic factors, particularly the genetic variations in cytokine genes.
  • This systematic review and meta-analysis evaluated the impact of specific single nucleotide polymorphisms (SNPs) in interleukin genes on the susceptibility or resistance to VL, using data from multiple scientific databases.
  • The analysis revealed significant associations between SNPs in the IFN-γ and IL-18 genes with VL, suggesting that these genetic variations could influence disease outcomes, while no significant links were found for IL-10 gene SNPs.
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  • - The paper reviews how enriched environments (EE) influence epigenetic changes in the brain under stressful conditions through an analysis of 14 relevant studies from databases like PubMed and Scopus.
  • - Findings indicate that after EE exposure, there are notable changes in microRNA expression and histone modifications, particularly in the prefrontal cortex and hippocampus, which affect brain plasticity and potentially improve behavioral outcomes.
  • - The study suggests that EE could serve as a simple, non-drug method to enhance brain health and mitigate symptoms associated with brain-affecting conditions.
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A ONECUT1 regulatory, non-coding region in pancreatic development and diabetes.

Cell Rep

November 2024

Institute of Molecular Oncology and Stem Cell Biology, Ulm University Hospital, Ulm, Germany. Electronic address:

In a patient with permanent neonatal syndromic diabetes clinically similar to cases with ONECUT1 biallelic mutations, we identified a disease-causing deletion located upstream of ONECUT1. Through genetic, genomic, and functional studies, we identified a crucial regulatory region acting as an enhancer of ONECUT1 specifically during pancreatic development. This enhancer region contains a low-frequency variant showing a strong association with type 2 diabetes and other glycemic traits, thus extending the contribution of this region to common forms of diabetes.

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Introduction: Fibrinolytic agents (FA) activate the fibrinolytic system, converting plasminogen into plasmin to break down fibrin. Their use for irrigation of abdominal abscesses is debated, and this meta-analysis evaluates their efficacy.

Methods: We searched PubMed, Embase, and Cochrane Central for randomized controlled trials (RCTs) comparing FA and saline in percutaneous drainage of abdominal abscesses.

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Objectives: We aimed to compare whether: (1) social media use (SMU) would induce a similar state of mental fatigue compared to the Modified Stroop task (MST); (2) the SMU and the MST would affect neuroelectric responses; and (3) sport-specific visuomotor performance in the taekwondo (TKD) athletes was impaired by mental fatigue.

Methods: Fifteen TKD athletes underwent a 60-min Modified Stroop Task (MST), engaged in SMU, or watched a documentary (CON) in a randomized order. Pre and post-each conditions they responded to a Stroop task (ST) while the event-related potentials (ERP) were measured.

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Letter to the editor - "Mediterranean ketogenic diet accounts for reduced pain frequency and intensity in patients with chronic migraine: A pilot study".

Clin Nutr

December 2024

Postgraduate Program in Neuropsychiatry and Behavioral Sciences, Center for Medical Sciences, Federal University of Pernambuco, Recife, Pernambuco, Brazil; Department of Physiotherapy, Health Sciences Center, FACOL University Center (UNIFACOL), Vitória de Santo Antão, Pernambuco, Brazil; Integrated Center for Neuroscience Technologies, FACOL University Center (UNIFACOL), Vitória de Santo Antão, Pernambuco, Brazil.

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Lung cancer is the leading cause of cancer-related death globally, with poor survival rates due mostly to a lack of early detection. The usual diagnostic technique includes a biopsy, which is frequently performed later in the disease's progression. In order to uncover processes that improve illness detection and prognosis, miRNA-21 emerges as a major miRNA identified in a variety of cancer types, including lung cancer.

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Introduction:  The question of whether assisted reproductive technologies (ART) and ovulation induction are related to a higher incidence of ovarian tumors (OTs) is still controversial in the literature.

Methods: We performed a comprehensive search of PubMed, Embase, and Web of Science databases for case-control and cohort studies that investigated ART and ovulation induction exposure as risk factors for OT in infertile women. Odds ratios (OR) with 95% confidence intervals (CI) were employed for all endpoints.

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Article Synopsis
  • Visceral leishmaniasis (VL) is a serious public health issue caused by protozoa and can be fatal if not treated, with current treatment options facing challenges like toxicity and drug resistance.
  • Novel derivatives of 1,2,4-oxadiazole have shown potential as new drug candidates, demonstrating high oral absorption and good bioavailability.
  • One particular derivative displayed strong selectivity against the parasite forms involved in VL, causing significant cell damage and decreasing mitochondrial function, indicating its effectiveness as a treatment option.
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: This letter to the editor presents suggestions for the therapeutic use of riboflavin in perinatal brain lesions caused by oxygen deprivation.: Clinical and preclinical studies using riboflavin conjugated with other components for the treatment of cerebral oxygen deprivation were included in the discussion.: Oxygen deprivation is predisposed by anoxia, hypoxia, or ischemia and causes severe early central damage, including sensorimotor impairment.

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  • - The study investigates how the SARS-CoV-2 virus infects host cells through its spike glycoprotein binding to the ACE2 receptor, focusing on how different cell types express heparan sulfate (HS) proteoglycans that may influence this process.
  • - Researchers conducted advanced simulations to analyze the interactions between the spike protein and ACE2, with emphasis on HS’s role in stabilizing the spike's active conformation and affecting the binding dynamics between the spike and ACE2.
  • - Findings suggest that HS enhances the virus's ability to infect cells, providing a potential target for developing anti-SARS-CoV-2 therapies through GAG derivatives.
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