8,919 results match your criteria: "FEDERAL UNIVERSITY OF MINAS GERAIS[Affiliation]"

Food consumption patterns and Framingham cardiovascular risk score among shift workers: A Nova-based approach.

Clin Nutr ESPEN

November 2024

School of Nutrition, Federal University of Ouro Preto, Ouro Preto, Minas Gerais, Brazil; Post-graduate Program in Health and Nutrition, Nutrition School, Federal University of Ouro Preto, Ouro Preto, Minas Gerais, Brazil; General Coordination of Non-Communicable Diseases (CGDNT), Department of Epidemiological Analysis and Surveillance of Non-Communicable Diseases (DAENT), Secretariat of Health and Environmental Surveillance (SVSA), Ministry of Health (MS), Brazil. Electronic address:

Objective: To evaluate the association between dietary quantity and variety, by extent and purpose of processing, and Framingham cardiovascular disease (CVD) risk score among rotating shift workers.

Methods: The cross-sectional study included male shift workers. Dietary intake was assessed using a 24-h recall method conducted by trained interviewers.

View Article and Find Full Text PDF

Peltophorum dubium, a common tree in areas close to agricultural activity in the Brazilian Cerrado, is vulnerable to damage from the drift of picloram, an herbicide widely used in pastures and agriculture in Brazil. The aim was to evaluate the application of 0.0; 19.

View Article and Find Full Text PDF

Purpose: This study aimed to evaluate association of accelerometry data with physical activity levels (PAL) measured by three questionnaires and to investigate their ability to discriminate physically inactive from active patients on hemodialysis.

Materials And Methods: A cross-sectional study was conducted. PAL were assessed by accelerometry and questionnaires: Human Activity Profile (HAP), International Physical Activity Questionnaire (IPAQ), and 36-Item Short Form Health Survey (SF-36).

View Article and Find Full Text PDF

Genetic selection for hyperprolific sows resulted in higher proportion of low birthweight piglets and greater birthweight variation within the litter, increasing preweaning mortality. There is evidence that altrenogest supplementation improves post-weaning reproductive performance through higher ovulation rates, and increased embryo survival. This study aimed to evaluate the impacts of altrenogest supplementation during the last week of lactation in primiparous sows on subsequent reproductive performance.

View Article and Find Full Text PDF

Stereotactic biopsies are essential for obtaining accurate histopathological analysis to guide treatment decisions for deep-seated brain lesions. Manually guided methods, while commonly used and highly precise, can be limited by potential inaccuracies and insufficient tissue sampling. The emerging robot-assisted (RA) techniques offer enhanced precision and could address these limitations for improved accuracy.

View Article and Find Full Text PDF

Methotrexate for osteoarthritis: a systematic review meta-analysis of randomized controlled trials.

Inflammopharmacology

November 2024

Department of Rheumatology, Clínica Reumatológica Fernando Pimentel, Recife, Brazil.

Background: Osteoarthritis (OA) is a common joint disorder causing pain and stiffness, with limited effective treatment options. Methotrexate, known for its anti-inflammatory properties in rheumatoid arthritis, is being explored as a treatment for OA. This study evaluates Methotrexate's efficacy compared to placebo in reducing OA symptoms, such as stiffness in the knee and hand, and its impact on pain, physical function.

View Article and Find Full Text PDF
Article Synopsis
  • Breast cancer is a major global health issue, necessitating new therapies due to treatment side effects and resistance.
  • Research focused on a synthetic compound (APO-3) derived from lapachol, finding it effective against a mouse breast cancer cell line (4T1), particularly when combined with the chemotherapy drug paclitaxel (PTX).
  • The combination of APO-3 and PTX showed enhanced cytotoxicity, reduced cancer cell migration, inhibited certain proteins related to cancer spread, and promoted cell death more effectively than each substance alone, suggesting a promising avenue for breast cancer treatment.
View Article and Find Full Text PDF

Objective: To examine the relationship between etiologically-based preterm birth sub-groups and early postnatal growth according to gestational age at birth.

Methods: Prospective, multinational, cohort study involving 15 hospitals that monitored preterm newborns to hospital discharge. Measures/exposures: maternal demographics; etiologically-based preterm birth sub-groups; very, moderate and late preterm categories, and feeding.

View Article and Find Full Text PDF

A novel pathogenic DICER1 gene variant is associated with hereditary multinodular goiter in an Argentine family as evidenced by clinical, biochemical and molecular genetic analysis.

Endocrine

November 2024

Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica, Departamento de Microbiología, Inmunología, Biotecnología y Genética/Cátedra de Genética, Buenos Aires, Argentina.

DICER1 syndrome is an autosomal-dominant disorder that results in malignant or benign tumors. A number of distinct pathogenic germline and somatic variants have been identified as causing multinodular goiter (MNG). The purpose of the present study was to identify and characterize the genetic cause underlying the familial form of MNG through a whole-exome sequencing (WES) analysis in an Argentine family with three affected siblings.

View Article and Find Full Text PDF

Enhancing Doxorubicin Detection: Multiphase Electroextraction for Efficient and Affordable UHPLC-DAD Analysis in Saliva.

Electrophoresis

November 2024

Laboratory of Microfluidics and Separations (LaMS), Department of Chemistry, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.

Attesting optimal drug concentrations in biological fluids is crucial to ensure precise dosage adjustment, to guarantee therapy adherence, and to manage side effects in chemotherapy. Accurate drug determination relies on liquid chromatography and advanced detectors, with sample preparation playing a pivotal role, especially in complex matrices such as biological fluids. This study introduces a multiphase electroextraction (MPEE) of doxorubicin (DOX) in saliva by utilizing a paper point, followed by ultra-high-performance liquid chromatography coupled to diode array detection.

View Article and Find Full Text PDF

Respiration is governed by a central rhythm and pattern generator, which has the pre-Bötzinger complex as the inspiratory oscillator initiating the coordinated activity of several respiratory muscles, including the diaphragm, intercostals, and upper airway muscles. The diaphragm is the main inspiratory pump muscle driving inflow, whereas dilator upper airway muscles, such as tongue muscles, reduce airway resistance during inspiration. Breathing exhibits a marked state-dependent pattern attributed to changes in neuromodulatory tone in respiratory-related brain regions, including decreases in noradrenaline and serotonin and increases in acetylcholine levels during rapid eye movement (REM) sleep.

View Article and Find Full Text PDF
Article Synopsis
  • COVID-19 patients often show abnormal immune responses and mental health issues during hospitalization, but the connection with gut microbiome has not been fully explored.
  • The study classified COVID-19 severity into three levels: low (27.4%), moderate (29.8%), and critical (42.8%), with common symptoms including fever (66.1%) and cough (55.6%), and notable rates of anxiety (27.3%) and depression (39%).
  • Findings indicate that more severe cases exhibited higher levels of systemic inflammation and reduced gut bacterial diversity, particularly in women and obese individuals, suggesting a relationship between gut health, mental health, and COVID-19 severity, pointing to the potential of using microbiome-focused treatments.
View Article and Find Full Text PDF

What are microsatellites and how to choose the best tool: a user-friendly review of SSR and 74 SSR mining tools.

Front Genet

November 2024

Laboratory of Simulation and Computational Biology - SIMBIC, High Performance Computing Center - CCAD, Federal University of Pará, Belém, Pará, Brazil.

Microsatellites, also known as SSR or STR, are essential molecular markers in genomic research, playing crucial roles in genetic mapping, population genetics, and evolutionary studies. Their applications range from plant breeding to forensics, highlighting their diverse utility across disciplines. Despite their widespread use, traditional methods for SSR analysis are often laborious and time-consuming, requiring significant resources and expertise.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to identify radiographic and clinical characteristics of post-traumatic transient apical breakdown (TAB) in luxated permanent teeth, using data from 56 patients treated over 31 years.
  • Analysis of 89 teeth showed that upper central incisors were most affected, with common injuries being extrusion and lateral luxation; TAB was characterized by changes in the periodontal ligament and root resorption.
  • The time for TAB to appear was generally around 3.2 months, with significant differences based on TAB patterns, and the average duration for regression was 9.1 months following the trauma.
View Article and Find Full Text PDF

The structure of the porcine uterine-conceptus interface is associated with gestational day, fetal size and sex.

Domest Anim Endocrinol

January 2025

Department of Morphology, Institute of Biological Sciences, Federal University of Minas Gerais, Av. Antônio Carlos, 6627, 31.270-901, Belo Horizonte, MG, Brazil. Electronic address:

This study aimed to characterize histological changes of the maternal-conceptus interface in feto-placental units associated with fetal weight and sex throughout pregnancy. Pregnant Large-White X Landrace gilts(n=18) were euthanized and hysterectomized on gestational days[GDs] 30(n=3), 45(n=5), 60(n=5), and 90(n=5). Intact cross-sections of fetoplacental interface associated with the lightest[LW] and normally-grown[NW] littermates were collected on GD30(n=4 per size).

View Article and Find Full Text PDF
Article Synopsis
  • Despite improvements in reducing maternal mortality worldwide, significant challenges remain, particularly in low- and middle-income countries.
  • Effective strategies to lower maternal mortality need a combination of health policy implementation and social development.
  • Primary care is crucial for recognizing risk factors and early signs of maternal health issues, while antenatal care addresses various conditions that can improve maternal outcomes.
View Article and Find Full Text PDF
Article Synopsis
  • * In a study, mice treated with W. paramesenteroides WpK4 showed increased intestinal mucus production, better villi regeneration, and 100% survival, compared to 60% survival in the control group after chemotherapy with 5-fluorouracil (5-FU).
  • * The probiotic strain can produce and metabolize tryptophan, and its protective effects are associated with increased expression of tryptophan-related molecules in the mice, but these benefits are negated when an AhR inhibitor is
View Article and Find Full Text PDF

Impact of the estrous cycle on brain monoamines and behavioral and respiratory responses to CO in mice.

Pflugers Arch

November 2024

Department of Animal Morphology and Physiology, College of Agricultural and Veterinarian Sciences, São Paulo State University, Rod. Prof. Paulo Donato Castellane S/N, Jaboticabal, SP, 14884-900, Brazil.

Article Synopsis
  • - The study examines how the estrous cycle affects the responses of female mice to carbon monoxide (CO), focusing on behaviors, brain chemistry, and physiological changes.
  • - While all phases of the estrous cycle resulted in similar escape behaviors in response to CO, the ventilation and metabolic responses varied, notably showing higher ventilation and lower body temperature during hypercapnia.
  • - The results indicate hypercapnia triggers panic-like behaviors in female mice and influences their hormone levels, but the phase of the estrous cycle does not alter the behavioral response to CO exposure.
View Article and Find Full Text PDF

spp. has emerged as a pathogen that is affecting global aquaculture, with , , and causing piscine lactococcosis. While antimicrobials are commonly used to treat diseases in aquaculture, reports of antimicrobial resistance in fish isolates are increasing.

View Article and Find Full Text PDF
Article Synopsis
  • The study looked at how the food options available around schools in Southern Brazil impact what ninth-grade students eat, focusing on both healthy and unhealthy food choices.
  • Data was collected from 449 students in two cities, with the food environment evaluated using a specific tool (AUDITNOVA) to assess both the types of foods available and their impact on student diets.
  • Results showed a significant relationship in Florianópolis where a poorer food environment was linked to higher unhealthy food consumption, while the smaller municipality revealed low healthy food intake with no significant findings on the relationship between food environment and consumption.
View Article and Find Full Text PDF

The family of individuals living with Down Syndrome (DS) often demonstrate high levels of stress associated with the demand for care and difficulties experienced in everyday life. The aim of this cross-sectional study was to assess perceived stress by parents/caregivers of individuals with DS and its association with general perceived self-efficacy and dental outcomes, considering the COVID-19 pandemic's impacts on family's daily activities and finances. A sample of 257 parents/caregivers answered a questionnaire with socioeconomic, dental, and behavioral variables and the short version of the Perceived Stress Scale and the General Perceived Self-Efficacy Scale.

View Article and Find Full Text PDF

This study evaluated the psychometric properties of the Portuguese version of Digital Health Literacy Instrument for Brazilian Adolescents (DHLI-BrA). Two hundred and sixty Brazilian adolescents answered the DHLI-BrA and the Brazilian version of quality-of-life and health literacy instruments: WHOQOL-Bref, eHEALS-BrA, NVS-BR, and REALMD-20. Then, they answered a questionnaire on sociodemographics, health, Internet access, and digital health aspects.

View Article and Find Full Text PDF

Conceptual Model on Access to Food in the Favela Food Environment.

Int J Environ Res Public Health

October 2024

Department of Nutrition, School of Nursing, Federal University of Minas Gerais, Belo Horizonte 31270-901, MG, Brazil.

The inequalities of Brazilian society are amplified in favelas, affecting access to basic sanitation, health, education services, and food. More research is needed to better understand the favela food environment and propose appropriate public food and nutrition policies to increase the availability of and access to healthy food. In this context, this study aimed to develop a conceptual model of the relationship between access to food and the favela food environment and its determinants.

View Article and Find Full Text PDF