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Photoacoustic-Based Intra- and Peritumoral Radiomics Nomogram for the Preoperative Prediction of Expression of Ki-67 in Breast Malignancy.

Acad Radiol

November 2024

Department of Ultrasound, The Second Clinical Medical College, Jinan University (Shenzhen People's Hospital), Shenzhen 518020, Guangdong, China (Z.H., M.W., Y.K., G.L., H.T., H.W., J.Z., S.M., J.X., F.D.); The Second Clinical Medical College, Jinan University, Shenzhen 518020, China (Z.H., M.W., Y.K., G.L., H.T., H.W., J.Z., S.M., J.X., F.D.). Electronic address:

Rationale And Objectives: This study investigated the preoperative predictive efficiency of radiomics derived from photoacoustic (PA) imaging, integrated with the clinical features of Ki-67 expression in malignant breast cancer (BC), with a focus on both intratumoral and peritumoral regions.

Methods: This study involved 359 patients, divided into a training set (n = 251) and a testing set (n = 108). Radiomic features were extracted from intratumoral and peritumoral regions using PA imaging.

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