3 results match your criteria: "Experimental Zooprophylactic Institute of Umbria and Marche Regions "Togo Rosati" (IZSUM)[Affiliation]"

Article Synopsis
  • - Toxoplasmosis is a common parasitic infection that often causes abortion and stillbirth in animals, especially in sheep and goats, but is rarely fatal in adult animals.
  • - A case study details a young three-month-old goat that died from acute systemic toxoplasmosis, showing symptoms like difficulty breathing, firm and mottled lungs, and generalized lymphadenopathy.
  • - Histopathological analysis confirmed necrotizing infections caused by T. gondii, with DNA tests verifying the presence of a type II strain responsible for the fatal outcome.
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Food allergy is a worldwide health problem that concerns infants to adults. The main health risk for sensitised individuals is due to the presence of traces of allergens as the result of an accidental contamination during food processing. The labelling of allergens such as sesame, pistachio, and macadamia nut on food products is mandatory according to Regulation (EU) N.

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First evaluation of endotoxins in veterinary autogenous vaccines produced in Italy by LAL assay.

Biologicals

September 2018

Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche "Togo Rosati" Pharmaceutical Unit, Via G. Salvemini 1, 06126, Perugia (PG), Italy.

Endotoxin contamination is a serious concern for manufacturers of biological products and vaccines in terms of not only quality but also safety parameters. We evaluated the endotoxin presence in different veterinary autogenous vaccines produced by the Pharmaceutical Unit at the Experimental Zooprophylactic Institute of Umbria and Marche "Togo Rosati" (IZSUM). According to the 3Rs principles (Replace, Reduce, Refine), which aim to progressively reduce animal use in the quality control process, we tested the vaccines obtained from gram-negative bacteria and adjuvants by the limulus amebocyte lysate (LAL) assay.

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