20 results match your criteria: "Experimental Research Centre ELPEN[Affiliation]"
Ann Med Surg (Lond)
December 2018
Obstetrics and Gynecology, London Deanery, United Kingdom.
Objectives: There is substantial lack of guidance when it comes to the implementation of non-technical skills (NTS) in undergraduate medical education. This review aimed to identify and critically evaluate published literature on learning strategies for NTS in undergraduate medical education and to derive a training framework targeted towards standardizing future training interventions.
Methods: A systematic review of the MEDLINE database was performed using a prospective protocol following PRISMA guidelines.
Background: Simulation-based learning (SBL) is an essential adjunct to modern surgical education. Our study aimed to evaluate the educational benefit and motivational impact of a pilot practical neurosurgical module.
Materials And Methods: 38 clinical medical students from several EU Medical Schools attended an international surgical course focused on teaching and learning basic surgical skills.
Eur J Trauma Emerg Surg
December 2019
School of Medicine, European University Cyprus, Nicosia, Cyprus.
Purpose: To investigate the effects of the combination of centhaquin and 6% hydroxyethyl starch 130/0.4 (HES 130/0.4) in a swine model of hemorrhagic shock.
View Article and Find Full Text PDFActa Neurochir (Wien)
September 2018
Experimental Research Centre ELPEN, Athens, Greece.
Introduction: Physiological hand tremor occurs naturally, due to oscillations of the upper extremities. Tremor can be exacerbated by stress and anxiety, interfering with fine motor tasks and potentially impact on surgical performance, particularly in microsurgery. We investigated the link between tremor, anxiety and performance in a neurosurgical module as part of an international surgical course.
View Article and Find Full Text PDFAnn Med Surg (Lond)
July 2018
esmsc Medical Education Research Group (eMERG Collaboration), Experimental Research Center ELPEN, Greece.
Background: The practice of evidence-based medicine and critical appraisal are essential for the modern doctor. Early engagement of medical students in research methodology is considered as a rising need for most medical school curricula; however, few peer-reviewed initiatives have been reported so far. We developed a Medical Education Research Group (eMERG) as part of a novel undergraduate surgical masterclass, which aimed to train undergraduate students on basic research methodology, as well as to motivate them to pursue a clinical and academic career in surgical specialties.
View Article and Find Full Text PDFAnticancer Res
June 2018
Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, U.S.A.
Background/aim: Our aim was to develop an animal model of the precancerous stages of colitis-associated carcinogenesis by modifying the established azoxymethane/dextran sulfate sodium (AOM/DSS) protocol.
Materials And Methods: Six mice were treated with varying cycles of DSS following AOM administration as above (group 1: three mice received three 5-day cycles of 3.0% DSS and group 2: three mice received three 7-day cycles of 2.
Indian J Surg
February 2018
4Aristotle University of Thessaloniki (AUTH), Thessaloniki, Greece.
Essential Skills in the Management of Surgical Cases (ESMSC) is an international wet lab simulation course aimed at undergraduate students. It combines basic science workshops, case-based lectures and ex vivo skills modules, as well as in vivo dissections using a swine model. This study aims to evaluate the effectiveness of high-fidelity In Vivo Simulation-Based Learning for undergraduate level trainees.
View Article and Find Full Text PDFBackground: Essential Skills in the Management of Surgical Cases (ESMSC) is a novel 3-day international undergraduate surgical masterclass. Its current curriculum (Cores integrated for Research-Ci4R) is built on a tetracore, multiclustered architecture combining high-fidelity and low-fidelity simulation-based learning (SBL), with applied and basic science case-based workshops, and non-technical skills modules. We aimed to report our experience in setting up ESMSC during the global financial crisis.
View Article and Find Full Text PDFJ Surg Educ
September 2019
Women's Health Research Unit, Queen Mary University of London, London, United Kingdom.
Objective: We aimed to identify and critically appraise all literature surrounding simulation-based learning (SBL) courses, to assess their relevance as tools for undergraduate surgical education, and create a design framework targeted at standardizing future SBL.
Methods: We performed a systematic review of the literature using a specific keyword strategy to search at MEDLINE database.
Results: Of the 2371 potentially eligible titles, 472 were shortlisted and only 40 explored active interventions in undergraduate medical education.
Blood Res
December 2017
Experimental Research Centre ELPEN Pharmaceuticals, S.A. Inc., Co., Pikermi, Greece.
J Invest Surg
March 2019
e Newham University Hospital, Bartshealth NHS Trust , London , UK.
Background: Essential Skills in the Management of Surgical Cases (ESMSC) is an international undergraduate surgical masterclass which combines ex vivo, dry lab and high fidelity in vivo simulation-based learning (SBL). It consists of 32 stations of skills-based learning, including open reduction internal fixation (ORIF) of fractures. Current literature suggests early involvement in skills-based learning at the undergraduate level is vital.
View Article and Find Full Text PDFCardiovasc Hematol Disord Drug Targets
July 2017
Experimental Research Centre ELPEN Pharmaceuticals, S.A. Inc., Co., Attiki. Greece.
Aim: This study compared the hematopoietic capacities of erythropoietin (Epo) and antioxidant drug U-74389G, based on 2 preliminary studies. The provided results on hematocrit levels augmentation were co-evaluated in a hypoxia reoxygenation protocol of an animal model.
Materials And Methods: Hematocrit levels were evaluated at the 60th reoxygenation min (for groups A, C and E) and at the 120th reoxygenation min (for groups B, D and F) in 60 rats.
Ann Med Surg (Lond)
December 2016
Background: Essential Skills in the management of Surgical Cases - ESMSC is an International Combined Applied Surgical Science and Wet Lab course aimed at the undergraduate level. ESMSC combines interactive basic science workshops and case-based learning, with basic surgical training modules (BST) on Ex Vivo and In Vivo swine model. In Vivo Dissections include more advanced modules i.
View Article and Find Full Text PDFPorto Biomed J
November 2016
Experimental Research Centre ELPEN Pharmaceuticals, S.A. Inc., Co., Pikermi, Attiki, Greece.
Background: This experimental study examined the effect of the antioxidant drug "U-74389G", on a rat model and particularly in a hypoxia - reoxygenation protocol. The effects of that molecule were studied hematologically using blood mean platelets volume (MPV) levels.
Methods: 40 rats of mean weight 231.
Redox Rep
January 2017
d European University Cyprus , School of Medicine, Nicosia , Cyprus.
The intestine is highly sensitive to ischemia/reperfusion (I/R) injury. Intestinal I/R may cause local tissue injury and disruption of the intestinal mucosal barrier, allowing the passage of viable bacteria and endotoxins from the gastrointestinal lumen to distant organs. This phenomenon, known as bacterial translocation (BT), may lead to systemic disorders with high morbidity and mortality.
View Article and Find Full Text PDFJ Invest Surg
April 2017
o Assistant Professor of Surgery , Aristotle University of Thessaloniki (AUTH).
Background: Undergraduate Surgical Education is becoming an essential element in the training of the future generation of safe and efficient surgeons. Essential Skills in the Management of Surgical Cases (ESMSC), is an international, joint applied surgical science and simulation-based learning wet lab course.
Methods: We performed a review of the existing literature on the topic of undergraduate surgical education.
Curr Urol
May 2016
Experimental Research Centre ELPEN Pharmaceuticals, S.A. Inc., Co., Greece.
Objective: The aim of this experimental study was to examine the effect of the antioxidant drug "U-74389G" on a rat model using an ischemia reperfusion protocol. The effect of U-74389G was studied biochemically by measuring mean blood creatinine levels.
Materials And Methods: Forty rats were used in the study.
In Vivo
September 2016
First Department of Surgery, Laiko General Hospital, University of Athens Medical School, Athens, Greece.
Background/aim: Radiofrequency ablation (RFA) with internally cooled electrodes is a technique for the in situ treatment of solid tumors, inducing characteristic pathological changes with limited clinical complications. Our purpose was to assess RFA-induced histological alterations and correlate them with clinical complications.
Materials And Methods: Using a porcine model, the pathology of RFA-induced kidney, liver and spleen lesions was associated with the postoperative course and clinical complications recorded.
Am J Emerg Med
August 2014
Hellenic Society of Cardiopulmonary Resuscitation, Athens, Greece; National and Kapodistrian University of Athens, Medical School, Aretaieio Hospital, 2nd Department of Ob&Gyn, Athens, Greece.
Background: In addition to its role in the endogenous control of erythropoiesis, recombinant human erythropoietin (rh-EPO) has been shown to exert tissue protective properties in various experimental models. However, its role in the cardiac arrest (CA) setting has not yet been adequately investigated.
Aim: The aim of this study is to examine the effect of rh-EPO in a pig model of ventricular fibrillation (VF)-induced CA.