1 results match your criteria: "Experimental Research Center and Medical Genetics Service[Affiliation]"
Polymorphisms in CYP19A1 and NFKB1 genes are associated with cutaneous melanoma risk in southern Brazilian patients.
Melanoma Res
August 2016
aDepartment of Dermatology, Hospital de Clínicas de Porto Alegre (HCPA) bDepartment of Genetics, Universidade Federal do Rio Grande do Sul (UFRGS), Experimental Research Center and Medical Genetics Service, HCPA cPostgraduate Program in Medical Sciences dDepartment of Statistics, UFRGS, Porto Alegre eLaboratory of Human and Medical Genetics, Universidade Federal do Pará (UFPA), Belém, Brazil.
Article Synopsis
- Melanoma is a deadly skin cancer influenced by genetic risk factors, specifically related to the NFKB1 and CYP19A1 gene variants.
- A case-control study involving 117 melanoma patients and 116 controls in southern Brazil found significant associations between specific genotypes and increased melanoma risk.
- The NFKB1 ATTG2/ATTG2 and CYP19A1 del/del genotypes may serve as genetic markers for melanoma susceptibility in this population.