4,230 results match your criteria: "Exercise-Induced Asthma"

This literature review focuses on diagnostics of equine asthma (EA), possible influencing factors on diagnostic techniques and latest developments in diagnosing horses during EA remission or with subclinical disease. Routine EA diagnostics include a clinical examination of the respiratory system with percussion and auscultation including a rebreathing examination, and clinical pathology including white blood cells and arterial blood gas analysis. Subsequent diagnostics include bronchoscopy to evaluate the amount and viscosity of respiratory secretion, bronchoalveolar lavage, and the cytology of tracheal aspirates (TAs) and bronchoalveolar lavage fluid (BALF).

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Diagnostic Testing in Exercise-Induced Bronchoconstriction.

Immunol Allergy Clin North Am

February 2025

Department of Respiratory Medicine, Thorax Institute, Hospital Maciel, Facultad de Medicina, Universidad de la República, 25 de Mayo 174, Montevideo 11000, Uruguay.

Article Synopsis
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Mechanisms and Biomarkers of Exercise-induced Bronchoconstriction: Current Insights and Future Directions.

Immunol Allergy Clin North Am

February 2025

School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK; Department of Respiratory Medicine, Leeds Teaching Hospitals NHS Trust, UK.

Exercise-induced bronchoconstriction (EIB) refers to temporary lower airway narrowing that occurs during or after vigorous physical exertion, with a high incidence in athletes and individuals with pre-existing asthma. The pathophysiology of EIB is not completely understood, but it is thought to involve a complex interplay among airway epithelial changes, immune responses, and environmental interactions. Phenotypic differences are apparent among those affected by EIB.

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Exercise-Induced Bronchoconstriction Background Prevalence Around the World.

Immunol Allergy Clin North Am

February 2025

Pulmonary Function Testing Laboratory, Instituto de Desarrollo e Innovación en Fisiología Respiratoria (INFIRE), Mexico City, Zitacuaro 22, CP 06170, Mexico.

Exercise-induced bronchoconstriction (EIB), subgrouped as exercise-induced bronchoconstriction with asthma (EIBa) or without asthma, is defined as acute airway narrowing that occurs during or after exercise. EIB has been described mostly in patients with asthma and athletes. Prevalence differs according to the subjects studied, challenge methods, and EIB definition.

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The next 5 years at the Interface of Exercise and the Airway.

Immunol Allergy Clin North Am

February 2025

Department of Respiratory Physiology, Deputy Directorate of Ancillary Diagnostic Services, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío villegas (INER), Instituto de Desarrollo e Innovación en Fisiología Respiratoria (INFIRE), Tlalpan 4502, Colonia Sección XVI, Tlalpan, Ciudad de México, CP 14080, México.

Exercise is strongly recommended in almost all populations for its beneficial effects on physical and mental health. This edition of Clinics features state-of-the-art reviews of the most commonly encountered respiratory causes of shortness of breath during exercise in active individuals, including nasal obstructions, exercise-induced laryngeal obstruction, excessive dynamic airways collapse, exercise-induced bronchoconstriction with and without asthma, and breathing-pattern disorder. The goals of this edition include summarizing knowledge of these conditions, creating a new wave of experts in the field, and inspiring readers to contribute to the field from around the globe.

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Exercise-Induced Laryngeal Obstruction History, Mechanisms, and Diagnostics Across the Globe.

Immunol Allergy Clin North Am

February 2025

Department of Kinesiology, Indiana University, School of Public Health-Bloomington, SPH Suite 112, 1025 East 7th Street, Bloomington, IN 47405, USA.

Article Synopsis
  • Exercise-induced laryngeal obstruction (EILO) is a challenging condition that affects mostly young people, with a prevalence of 5% to 8%, and has recently been categorized under inducible laryngeal obstruction.
  • Diagnosing EILO is difficult, but continuous laryngoscopy during exercise is considered the best method for accurate diagnosis.
  • Effective management requires teamwork among healthcare professionals and standardized evaluation methods, while future studies should aim to understand the condition better and enhance treatment outcomes.
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Article Synopsis
  • * Short-acting beta-agonists are the main treatment recommended for managing symptoms, and it's essential for patients, especially children, to avoid triggers that can worsen their condition.
  • * Physicians should regularly evaluate treatment effectiveness, but athletes may need specialized testing to create personalized management plans that balance health and performance.
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[Clinical diagnosis and management of wheat and buckwheat allergy: application and prospects of allergen component diagnostics].

Zhonghua Yu Fang Yi Xue Za Zhi

November 2024

Department of Clinical Laboratory of the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou510120, China.

Article Synopsis
  • - Wheat and buckwheat allergies significantly affect patients' health and well-being, with wheat allergy including various types such as food allergies and exercise-induced reactions, while buckwheat allergy is becoming more recognized in certain areas.
  • - Advanced diagnostic technologies that identify specific allergen components, like ω-5 gliadin, are enhancing the accuracy of allergy diagnosis and management, with oral challenge tests being the gold standard.
  • - Ongoing research focuses on understanding the characteristics of these allergens to improve diagnostic tools and treatment strategies, ultimately aiming to enhance patient care and quality of life, as highlighted in recent guidelines by the European Academy of Allergy and Clinical Immunology.
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Article Synopsis
  • Occupational exposure to irritants leads to poor asthma control, but the long-term effects on irritant-induced occupational asthma (IIA) patients are not well understood.
  • A study evaluated 28 IIA patients years after diagnosis, measuring lung function, bronchial responsiveness, inflammation, and exercise capacity, revealing that many still had poor asthma control despite normal lung function.
  • While most participants showed a slight improvement in asthma control over time, reduced physical capacity was prevalent and linked to inadequate symptom management and heavy medication use.*
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Background: Periostin and human chitinase-3-like protein 1 (YKL-40) have been suggested to be involved in the development of airway fibrosis and remodeling. This study aimed to investigate the relationship between serum periostin levels and airway hyperresponsiveness (AHR) and between serum YKL-40 levels and AHR in children with asthma, comparing periostin as a marker for Th2 inflammation and atopy with YKL-40.

Methods: The study involved children aged 6-15 years, comprising 75 with asthma and 29 healthy controls.

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Article Synopsis
  • Previous animal studies indicated concerns about salbutamol's effects on lung injury when exposed to ozone air pollution.
  • A double-blind, randomized, placebo-controlled study involved 18 participants with exercise-induced bronchospasm (EIB) testing the impacts of salbutamol in both ozone and room air during exercise.
  • Results showed that salbutamol significantly improved lung function without increasing airway inflammation, suggesting it is safe for EIB patients to use the medication during high ozone conditions.
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Article Synopsis
  • The study explored the effects of daily tangeretin combined with whey protein on exercise-induced bronchoconstriction (EIB) in professional athletes over four weeks.
  • It involved 30 athletes divided into a treatment group (TIG) receiving the supplement and a placebo control group (PCG), with various tests measuring lung function and inflammatory markers before and after the intervention.
  • Results indicated that the supplement improved lung function (FEV), reduced inflammation markers (IL-5, IL-8, CC16, IgE), and decreased certain blood cell counts, leading to enhanced exercise tolerance in the TIG compared to the PCG.
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Investigation of exertional dyspnoea by cardiopulmonary exercise testing with continuous laryngoscopy.

J Sci Med Sport

September 2024

Asthma, Allergy and Clinical Immunology Service, Alfred Health, Australia; Central Clinical School, Monash University, Australia.

Article Synopsis
  • Abnormal breathlessness during intense exercise can result from several conditions like exercise-induced bronchospasm, laryngeal obstruction, or breathing pattern disorders, often missed in regular tests.
  • A retrospective study involved 24 patients, including professional athletes, where advanced testing revealed specific conditions in 66.7% of cases, leading to tailored treatment plans.
  • Significant findings included that 38% had exercise-induced laryngeal obstruction, predominantly in younger athletes, and highlighted the need for specialized follow-up and interventions based on individual diagnoses.
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Diagnosis and Management of Exercise-induced Laryngeal Obstruction (EILO): Initial Results of a Multidisciplinary Team.

Arch Bronconeumol

September 2024

Otorhinolaryngology Department, Hospital del Mar, Barcelona, Spain; Hospital del Mar Research Institute, Barcelona, Spain; Department of Medicine and Life Sciences (MELIS), Universitat Pompeu Fabra (UPF), Barcelona, Spain.

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Article Synopsis
  • A study on pulmonary rehabilitation (PR) tailored for difficult-to-treat asthma in individuals with a BMI ≥25 kg/m shows positive outcomes immediately after 8 weeks and at one-year follow-up.
  • Out of 92 participants, significant improvements were noted in asthma control, breathlessness levels, and frequency of exacerbations over the study period.
  • Results indicate that those with worse asthma control at the start were more likely to see significant benefits from the PR, whereas baseline BMI did not predict the level of improvement.
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Article Synopsis
  • This study investigates how case-level American College of Medical Genetics (ACMG) criteria can clarify the pathogenicity of ultrarare variants causing Anderson-Fabry disease, especially when standard gene and variant-level analyses are inconclusive.
  • A 52-year-old woman presented symptoms like shortness of breath and chest pain, and family screening revealed affected and unaffected siblings, with some presenting with related symptoms indicating possible genetic connections to the disease.
  • Endomyocardial biopsies and advanced genetic testing initially classified a specific variant as uncertain, but incorporating functional data from biopsies and familial segregation eventually led to its reclassification as Likely Pathogenic/Pathogenic.
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Article Synopsis
  • - The study aimed to investigate how factors related to urban, suburban, and rural schools impact the prevalence of allergic and respiratory conditions among teachers in Massachusetts.
  • - Findings revealed that male teachers reported more adverse breathing symptoms, and rural teachers experienced higher rates of respiratory issues, including disruptive cough-related sleep.
  • - Results also indicated that public school teachers faced more respiratory symptoms than their private school counterparts, highlighting significant disparities that call for further research on potential solutions.
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Exercise-induced bronchoconstriction.

Nursing

October 2024

Bill Pruitt is a consultant and a member of the Nursing2024 Editorial Board. Karen L. Gregory is an assistant professor at Georgetown University in Washington, DC. Audra Cochran is an internal medicine resident, PGY-3, at the Keesler Medical Center in Biloxi, MS.

Article Synopsis
  • Exercise-induced bronchospasm (EIB) is a common issue, especially in children and elite athletes, but it's often misunderstood and can be mistakenly blamed on lack of fitness.
  • Many individuals experiencing EIB may reduce or avoid exercise due to symptoms, which can impact their health and fitness levels.
  • The article covers EIB's management and offers strategies for nurses to support patients managing this condition.
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Getting in Shape: Updates in Exercise Anaphylaxis.

Curr Allergy Asthma Rep

November 2024

Department of Pediatrics, Division of Pulmonology, Allergy & Immunology, University of Tennessee Health Science Center, LeBonheur Children's Hospital, 51 N. Dunlap Street, Suite 400, Memphis, TN, 38105, USA.

Article Synopsis
  • Exercise-induced anaphylaxis (EIA) is challenging to diagnose due to the influence of co-factors and the absence of consistent testing methods.
  • Recent research indicates that EIA may not be simply categorized into food-independent or food-dependent types, highlighting the complexity of its triggers, including food, medications, and alcohol.
  • Clinicians can enhance patient care by recognizing how these co-factors contribute to EIA symptoms, allowing for more personalized treatment strategies and improved patient quality of life.
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Article Synopsis
  • - A 24-year-old female developed adult-onset asthma after experiencing mildly symptomatic COVID-19, despite having no previous respiratory issues.
  • - Persistent symptoms like fatigue, exercise-related shortness of breath, and cough led to lung function testing, which revealed issues despite normal CT scans.
  • - Treatment with Budesonide/formoterol showed improvement, but further testing confirmed bronchial hyperreactivity, highlighting the need for awareness of lasting respiratory symptoms post-COVID and the initiation of research into the causes.
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Competitive Swim Breathing: A Survey-Informed Tutorial for Speech-Language Pathologists Who Treat EILO.

J Voice

September 2024

Department of Speech, Language & Hearing Sciences, Auburn University, Auburn, Alabama. Electronic address:

Article Synopsis
  • * A survey was conducted with 62 competitive swimmers about their breathing techniques, showing a preference for trickle breathing and variations based on training versus competition.
  • * Findings suggest that individual breathing strategies are vital for addressing EILO, highlighting the need for tailored clinical approaches rather than a one-size-fits-all solution.
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