Fast parametric curve matching (FPCM) for automatic spike detection.

. Epilepsy is a widely spread neurological disease, whose treatment often requires resection of the pathological cortical tissue. Interictal spike analysis observed in the non-invasively collected EEG or MEG data offers an attractive way to localize epileptogenic cortical structures for surgery planning purposes.

[Electroencephalography in acute stroke].

Objective: To determine the incidence of non-convulsive status epilepticus, epileptiform activity, rhythmic and periodic patterns in patients with acute stroke.

Material And Method: An analysis of electroencephalography (EEG) in 86 stroke patients in the neurointensive care unit of the tertiary medical center was performed. Criteria for starting EEG recording were epileptic seizures or clinical suspicion of uncontrolled epileptic status.

[Anxiety and depressive psychopathological characteristics of patients with multiple sclerosis at different stages of disease].

Aim: To study the development of anxiety and depressive disorders in patients with exacerbated multiple sclerosis (MS).

Material And Methods: Forty-three patients with MS were included in the study (women 74.4%, mean age 33.

[Influence of psychopathological factors and personality traits on the results of the study of quality of life in patients with multiple sclerosis].

Aim: To study the influence of psychopathological factors and personality traits on the results of the study of quality of life (QoL) in patients with multiple sclerosis (MS).

Material And Methods: Forty-three patients with relapsing MS were included in the study (74.4% female; mean age 33.

[Rhythmic and periodic EEG patterns. Classification and clinical significance.].

The review presents the methodology of electroencephalography (EEG) background analysis, sporadic epileptiform discharges classification, and description of the rhythmic and periodic patterns in patients with primary and secondary brain damage. It describes the process of decision making in starting non-convulsive status epilepticus treatment of patients with EEG-verified non-convulsive status epilepticus and the signs of 'malignant' patterns indicating the irreversibility of brain injury.

[Posttraumatic seizures: a prospective cohort study].

Aim: To evaluate the incidence and risk factors for posttraumatic seizures (PTS).

Material And Methods: The authors conducted a prospective study of 237 patients with TBI of varying severity. The patients were hospitalized and examined in Moscow neurosurgery departments.

[Predictors of remote outcomes of brain injury].

Aim: To determine predictors of remote outcomes of complex combat brain injury.

Material And Methods: A survey of 145 combatants with long-term combat injury (from 1 to 10 years) was conducted. Responses were received from 30 people from 18 regions of the Russian Federation.

[Depakine: 25 years in Russia].

The article summarizes domestic and international studies on the development and clinical investigation of valproates including multiple studies of a research team directed by the author. Valproate targets are considered in biological and clinical aspects. A spectrum of action and advantages of the brand drug (depakine) compared to generics and other antiepileptic drugs are discussed.

[W. Griesinger - a famous European psychiatrist (the 200 anniversary of birth)].

The article contains curriculum vitae of W. Griesinger and an analysis of the clinical-psychopathological approach developed by him for studying illnesses and their systematization. The stages of psychosis' progression in dynamics are shown.

[A role of clinical, psychological and social factors in the formation of hetero - and self-aggressive behavior of women serving time in a correctional facility].

Aim: To define a role of clinical, psychological and social factors in the development of aggressive behavior in women.

Material And Methods: A total of 1054 women serving their sentence in a penal colony were stratified into three groups: group 1 - 435 women with heteroaggressive behavior, group 2 - 298 women with self-aggressive behavior, group 3 (control group) - 321 woman without aggressive behavior. Clinical, psychological, sociological, and statistical methods were used.

[The development of ideas about the organization of the speech system].

This work represents an insight into a problem of studying one of the higher mental functions of humans - speech, its primary role in the development of man as a biosocial being. Various concepts of speech and the problem of the dominance of cerebral hemispheres in language function are analyzed. It touched upon the ontogenesis of hemispheric asymmetry.

[The clinical predictors of heteroaggressive behaviour of the women serving sentence in penitentiary].

Aim: To identify clinical predictors of heteroaggressive behavior.

Material And Methods: Three hundreds and three women serving sentence in a penal colony were examined using clinical, neurologic and statistical methods. The main group consisted of 225 women with heteroaggressive behavior, the control group included 78 women without aggressive behavior.

[Russian experience of lacosamide (vimpat) usage in treatment of uncontrolled focal epilepsy].

Unlabelled: Many patients with epilepsy receive treatment in polytherapy. Selection of antiepileptic drugs (AEDs) for the combination should be carried out in accordance with the principles of rational polytherapy, taking into account the mechanism of action, pharmacokinetic (PK) and pharmacodynamic (PD) properties of drugs. Along with levetiracetam, gabapentin, vigabatrin and pregabalin, lacosamide (LCM) shows superior PK profile in rating of all AED and can be combined with any of them.

[Quality of life of adult patients with cryptogenic epilepsy].

Aim: To determine a position of cryptogenic epilepsy (CE) in relation to idiopathic epilepsy (IE) and symptomatic epilepsy (SE) in the aspect of patients' quality-of-life.

Material And Methods: One hundred and fifty patients, including 90 with CE, 30 with SE and 30 with IE, were examined. The severity of epileptic seizures assessed with the NHS3, anxiety and depression assessed with the HADS, sleep disorders, quality-of-life measured with the Qolie-89 were studied.

[A comparative analysis of multiple linear models of medical service satisfaction among inpatients with borderline disorders at first-time admission and rehospitalization].

Aim: To find out the factors of satisfaction with psychiatric help in inpatients with neurotic and depressive disorders depending on the moment of satisfaction evaluation and patients' treatment experience.

Material And Methods: The sample included 266 first-time admission inpatients (satisfaction was evaluated at the moment of discharge) and 134 rehospitalized inpatients (satisfaction with previous treatment was evaluated at the moment of discharge; satisfaction with current treatment was evaluated at the moment of rehospitalization). The survey was performed using a questionnaire designed for this study.

[Photomatrix LED therapy in patients with post-stroke arthropathy of the shoulder joint].

Aim: To assess the impact of quasi-monochromatic partially coherent infra-red radiation on the dynamics of recovery of the affected joint and the hemostatic system in patients with post-stroke arthropathy of the shoulder joint.

Material And Methods: Fifty-five patients in the early, late and residual period of ischemic stroke were studied. Group I consisted of 27 patients who underwent 10 sessions of photomatrix therapy (wavelength 600 nm) on the affected joint, lasting for 10 minutes.

[Modeling of hemodynamic changes in the aneurysm of the middle cerebral artery depending on the pathology of the parent artery].

Objective: To examine the influence of the parent artery pathology on the local hemodynamics on the level of aneurysm.

Material And Methods: Mathematical models of the arteriovenous malformation (AVM) were built on the CT-angiography data of real patients. To simulate the thrombosis, the parent artery and its branches were sequentially turned off in the model 1.

[Algorithms of using valproic acid drugs in women].

Characteristics of using valproic acid drugs in women, from puberty to menopause period, are reviewed. Based on initial treatment efficacy, type of epileptic seizures and a form of epilepsy, the author emphasizes the practical use of valproates during pregnancy in dependence on the situation. Several scenarios of pregnancy course and possible treatment tactics are presented.

[Photosensitivity, epilepsy, the occipital and frontal cortex].

This article discusses the features of the structural-functional organization of the visual distance perception which, in contrast to other distant sensory systems, has not only afferent but also efferent part--the frontal visual field and, smooth and stripy muscles of the eye which accordingly support the visual function. The increasing importance of the efferent component of the visual system in the present conditions of real and virtual movements of visual objects is shown. The case of photosensitivity in epilepsy proves the fact that the efferent component of the visual system can react in a protective way to the rhythmic photostimulation.