The study aimed to compare the effectiveness of estradiol valerate plus dienogest (E(2)V/DNG) versus ethinylestradiol plus levonorgestrel (EE/LNG) in reducing dysmenorrheic pain in women aged 14-50.
During the trial, 507 women were randomized to take either treatment for three 28-day cycles, with their pain levels recorded daily.
Results showed that both treatments significantly reduced the number of days with pain, but the difference in outcomes was not statistically significant (P = 0.34).