133 results match your criteria: "Etlik Zubeyde Hanım Education and Research Hospital[Affiliation]"

Background: Preeclampsia is a serious pregnancy complication requiring early detection to improve outcomes. Profilin-1 (PFN1), linked to vascular dysfunction, may serve as a biomarker for diagnosing preeclampsia and predicting adverse neonatal outcomes. The aim of this study was to determine the serum Profilin-1 levels in patients diagnosed with preeclampsia and to investigate its association with disease severity and adverse neonatal outcomes.

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Blood-Based Clinical Biomarkers of Inflammation and Nutrition in Hyperemesis Gravidarum.

J Clin Med

November 2024

Department of Obstetrics and Gynecology, Health Sciences University Etlik Zubeyde Hanim Maternity, Teaching and Research Hospital, 06010 Ankara, Turkey.

: In this study, the aim was to investigate blood-based clinical biomarkers of inflammation and nutrition indices in hyperemesis gravidarum (HG). : This retrospective case-control study was conducted at a tertiary hospital between 2018 and 2022. A total of 820 pregnant women were enrolled in this study; 410 pregnant women were diagnosed with HG (HG group) at 6-14 weeks of gestation, and 410 pregnant women were healthy controls (control group) in the same gestational weeks.

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Reproductive performance and obstetric outcomes after hysteroscopic septum resection.

Eur J Contracept Reprod Health Care

December 2024

Etlik Zübeyde Hanım Women Health Education and Research Hospital, University of Medical Sciences, Etlik, Ankara, Turkey.

Purpose: The aim of this retrospective cohort study was to investigate the effects of hysteroscopic uterine septum resection on the clinical pregnancy rate (CPR), live birth rate (LBR) and miscarriage rate.

Materials And Method(s): Hospital records of consecutive patients who underwent hysteroscopic uterine septum resection between February 2021 and December 2022 were reviewed. They were telephoned and interviewed about their reproductive performance after surgery, and pregnancy outcomes, if achieved.

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Objective: The aim of the study was to investigate the role of systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), and pan-immune inflammation value (PIV) calculated from first trimester complete blood count (CBC) in predicting preeclampsia without (PE) and with severe features (PE-SF).

Methods: This retrospective cohort study included 126 women with PE, 126 women with PE-SF, and 126 women with healthy, normotensive pregnancies delivered at a large tertiary referral hospital between 2018 and 2022. The main outcome measures were SII, SIRI, and PIV.

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Article Synopsis
  • The Hedgehog signaling pathway is important for folliculogenesis, but its relationship with FF-MAS oxysterol in this process, especially in conditions like PCOS, is not well understood.
  • *The study found that FF-MAS enhances the proliferation of granulosa cells (GCs) and increases key Hedgehog pathway components (SMO and Gli1) even in the presence of an inhibitor, suggesting its significant role in follicular development.
  • *Ultimately, this research could lead to new strategies for improving human IVF treatments by leveraging FF-MAS's effects on GCs and folliculogenesis.
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Objectives: This study aimed to investigate the relationship between controlling nutritional status index (CONUT) and prognostic nutrition index (PNI) scores that are used to evaluate nutritional status and GDM. Also, lipid abnormalities and albumin levels in pregnant women with normal glucose tolerance and GDM were researched.

Material And Methods: This study was conducted as a retrospective study at Ankara Etlik City Hospital, Turkey.

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Article Synopsis
  • - This study evaluates the effectiveness of inflammation indexes (like SII and NLR) for diagnosing intrahepatic cholestasis of pregnancy (ICP) by reviewing medical records of 242 patients, including 121 with ICP and 121 healthy controls.
  • - Key findings showed significant differences in immune cell counts and liver enzyme levels between the ICP group and controls, with SII and NLR being notably higher in ICP patients.
  • - The study concludes that these systemic inflammation indices can be cost-effective and rapid diagnostic tools for ICP, suggesting they could improve patient outcomes when integrated into standard clinical practice.
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Article Synopsis
  • The study examines reproductive outcomes over two years for women with tubal ectopic pregnancies (EP) treated by surgery, methotrexate (MTX), or expectant management.
  • Over 900 patients were analyzed, revealing that those who underwent surgery had a significantly higher rate of no pregnancies compared to those receiving MTX or expectant management.
  • The findings suggest that expectant management and MTX therapy offer better chances for future pregnancies than surgical treatment, highlighting the importance of timely diagnosis and treatment choice.
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Introduction: The aim of the study was to analyse the clinical and demographic features of infants with gestational age (GA) of 32-37 weeks and birth weight (BW) of >1,500 g who developed treatment requiring retinopathy of prematurity (ROP).

Methods: Data on the infants with a GA of 32-37 weeks and BW >1,500 g who developed treatment requiring ROP (TR-ROP) were collected retrospectively from the 33 ROP centres in Turkiye. GA, BW, type of hospital, neonatal intensive care units (NICUs) level, presence of an ophthalmologist and neonatologist in the same hospital, length of stay in NICU, duration of oxygen therapy, comorbidities, type of ROP, and timing for TR-ROP development were analysed.

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Objectives: Placental abruption (PA) is associated with adverse maternal and neonatal outcomes and has an etiological mechanism that is not yet fully understood. The prediction of PA, which has been the subject of numerous studies, remains a challenge. In particular, there is evidence that PA can be considered a chronic process.

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Introduction: To determine a cut-off value for systemic immune-inflammation index (SII) (neutrophil × platelet/lymphocyte) in the prediction of fetal growth restriction (FGR).

Materials And Methods: This case-control study was conducted retrospectively at the Obstetrics-Gynecology and Perinatology Clinics of Etlik Zubeyde Hanim Women's Health Education and Training Hospital. Singleton pregnant women with late-onset FGR who were followed up in outpatient clinics or hospitalized and whose pregnancy resulted at our hospital were included in the study group (group I).

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Article Synopsis
  • - The study investigates the incidence of hypoxic ischemic encephalopathy (HIE) in infants ≥36 weeks gestational age in Turkey, finding an incidence rate of 2.13 per 1000 live births, with varying severity levels among those affected.
  • - Among infants with HIE, therapeutic hypothermia (TH) was notably administered to 34.5% of those with mild HIE, while factors like gestational age affected mortality rates, especially in those born at 34-35 weeks.
  • - Despite an unchanged incidence of HIE, the study revealed a decreased mortality rate and no significant impact of TH timing on MRI findings or mortality.
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Objective The aim of this study was to investigate the association between poor neonatal outcomes and BDNF (brain-derived neurotrophic factor) levels. We aimed to predict the need for an emergency cesarean and prevent unnecessary interventions in cases complicated with meconium-stained amniotic fluid (MSAF). Methods This study was designed as a case-control study including three groups.

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Purpose: Evaluation of the effect of maternal nifedipine treatment on total uterine artery blood volume flow rate (TVFR).

Methods: In this prospective study, 43 women who were admitted to the Perinatology Department of the University of Health Sciences Etlik Zübeyde Hanım Gynecology Training and Research Hospital, with the diagnosis of the threat of preterm labor, and 40 healthy pregnant women, who were randomly selected as the control group, were evaluated between July 1, 2018, and September 1, 2018. A transabdominal ultrasound examination of uterine arteries was performed both before and 48 hours after administration of oral nifedipine for TVFR measurement.

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The Fathers' Fear of Childbirth Scale: a Turkish validity and reliability study.

J Reprod Infant Psychol

June 2024

Department of Obstetrics and Gynecology, Etlik Zübeyde Hanım Women's Health Education and Research Hospital, University of Health Sciences, Ankara, Turkiye.

Purpose: Fathers' Fear of Childbirth Scale (FFCS) was developed specifically to measure fathers' fear of childbirth. The aim of this study was to investigate the Turkish validity and reliability of the FFCS.

Design: This study used a cross-sectional and methodological design.

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Objective: Optimal care in the delivery room is important to decrease neonatal morbidity and mortality. We aimed to evaluate neonatal resuscitation practices in Turkish centers.

Materials And Methods: A cross-sectional survey consisted of a 91-item questionnaire focused on delivery room practices in neonatal resuscitation and was sent to 50 Turkish centers.

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Purpose: To investigate the role of partial human papillomavirus (HPV) genotyping tests in predicting the diagnosis of high-grade cervical intraepithelial lesion and cancer (HSIL +) as a result of colposcopic histopathology.

Materials And Methods: The study included 2872 patients who presented at our colposcopy unit between January 1, 2015 and December 31, 2019 and underwent colposcopy for the first time. The patients were compared in terms of HSIL + results as HPV 16/18 and HPV other type positive groups.

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Introduction: The study aimed to investigate the effectiveness of topical anesthetic drops in reducing the pain associated with mydriatic eye drops prior to the retinopathy of prematurity (ROP) examination.

Methods: Premature infants who underwent first-time ROP examinations in an outpatient setting were included in this randomized controlled trial. The study group included the infants who were administered topical anesthesia prior to the first mydriatic drops, and the control group included the infants who were given preservative-free artificial tear drops.

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Objectives: To evaluate the maternal serum ischemia-modified albumin (IMA) concentration as an oxidative stress biomarker in pregnancies complicated by preterm pre-labor rupture of membranes (PPROM) without maternal clinical infection and compare these results with healthy pregnancies.

Material And Methods: The present cohort study included 40 pregnancies complicated by PPROM and 49 similar gestational age healthy pregnancies in the third trimester of gestation. Maternal venous blood specimens were obtained at the day of first diagnosis.

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Article Synopsis
  • This study evaluated the Quality of Life (QoL) and sexual function in women undergoing total abdominal vs. total laparoscopic hysterectomy, using validated questionnaires before and six months after surgery.
  • A total of 121 patients participated, with 65 undergoing abdominal hysterectomy and 56 laparoscopic; 104 completed the follow-up surveys.
  • Results indicated that women in the laparoscopic group reported greater improvements in QoL and better sexual function scores post-surgery compared to the abdominal group, although some sexual dysfunction metrics showed no significant differences between groups.*
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Familial Mediterranean fever (FMF) is a monogenic autoinflammatory disorder with recurrent fever, abdominal pain, serositis, articular manifestations, erysipelas-like erythema, and renal complications as its main features. Caused by the mutations in the MEditerranean FeVer (MEFV) gene, it mainly affects people of Mediterranean descent with a higher incidence in the Turkish, Jewish, Arabic, and Armenian populations. As our understanding of FMF improves, it becomes clearer that we are facing with a more complex picture of FMF with respect to its pathogenesis, penetrance, variant type (gain-of-function vs.

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Complementary and Alternative Medicine Attitudes of Gynecologic Patients: Experience in a Tertiary Clinic.

Rev Bras Ginecol Obstet

November 2021

Department of Obstetrics and Gynecology, Etlik Zübeyde Hanım Women's Health Education and Research Hospital, University of Health Sciences, Ankara, Turkey.

Objective:  To evaluate the knowledge, attitudes, and behaviors regarding complementary and alternative medicine methods of patients who were admitted to gynecology outpatient clinics.

Methods:  In the present survey, a questionnaire on complementary and alternative medicine practices was applied on 1,000 women (ages between 18 and 83 years old) who were admitted to the gynecology outpatient clinic of a tertiary maternity hospital. Demographic features and knowledge, attitudes, and behaviors about these methods were inquired in face-to-face interviews.

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Survival outcomes of women with grade 3 endometrioid endometrial cancer: the impact of adjuvant treatment strategies.

Arch Gynecol Obstet

March 2022

Department of Gynecology with Center for Oncological Surgery, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Virchow Campus Clinic, Charité Medical University, 13353, Berlin, Germany.

Article Synopsis
  • The study aimed to evaluate treatment options and recurrence patterns for patients with grade 3 endometrioid endometrial cancer (G3-EEC) by analyzing data from 11 gynecological oncology centers over a 22-year period.
  • Among 465 women analyzed, the 5-year disease-free survival (DFS) rate was 50.3%, and the overall survival (OS) rate was 57.6%, highlighting significant outcomes based on surgical success.
  • The findings indicated that inadequate lymphadenectomy negatively impacted survival rates, serving as an independent prognostic factor, while optimal surgery and adequate lymphadenectomy positively correlated with better survival in advanced-stage patients.
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The pneumatic tube transport system (PTS) is used frequently for the transport of samples in hospitals. Effects of PTS on urine components are unknown. In our study, we aim to examine the influence of PTS on the quality of routine urine microscopic parameters.

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Aim: In our study, the frequency of sleep disturbances in pregnancy, the reasons underlying the low quality of sleep, clinical factors, and the effects on quality of life were investigated.

Methods: The study was planned as a prospective study and included 189 pregnant women. Clinical features, laboratory results, socio-demographic status, obstetric and medical anamnesis were evaluated.

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