Magnitude of Depression and Associated Factors in Women Living With HIV in Northwest, Ethiopia: Mediation Analysis.

Depression in women living with HIV (WLWHIV), is one of the most common public health concerns worldwide. Depression has a negative impact on antiretroviral therapy (ART) adherence, quality of life, poor HIV treatment outcomes, and mortality. However, there is a paucity of evidence in low-income countries such as Ethiopia in WLWHIV.

Identifying the Factors That Drive Health Service Utilization Among Healthy and Non-Healthy Agers in a Sample of Older Ethiopians: A Cross-Sectional Study.

Background And Aims: Population aging is associated with the rising incidence of chronic illness. This presents a significant challenge to healthcare systems, particularly in developing countries, as untreated chronic conditions can lead to years of disability and loss of independence straining health budgets and resources. Promoting healthy aging can be one avenue for mitigating these challenges.

Health-promoting lifestyle behaviors and their associated factors among pregnant women in Debre Markos, northwest Ethiopia: a cross-sectional study.

Introduction: Promoting healthy lifestyle behaviors during pregnancy is a crucial health promotion strategy that could reduce pregnancy-related complications that may harm women and their fetuses. However, very few studies have assessed the prevalence of health-promoting lifestyle behaviors among pregnant women in Ethiopia. This study aimed to evaluate the extent and associated factors of health-promoting lifestyle behaviors among pregnant women in public health institutions in Debre Markos, northwest Ethiopia.

Antioxidative and Anticancer Potential of Luteolin: A Comprehensive Approach Against Wide Range of Human Malignancies.

Luteolin is widely distributed phytochemical, a flavonoid, in kingdom plantae. Luteolin with potential antioxidant activity prevent ROS-induced damages and reduce oxidative stress which is mainly responsible in pathogenesis of many diseases. Several chemo preventive activities and therapeutic benefits are associated with luteolin.

adapted to steppe-desert climate extremes one million years ago.

Questions about when early members of the genus adapted to extreme environments like deserts and rainforests have traditionally focused on . Here, we present multidisciplinary evidence from Engaji Nanyori in Tanzania's Oldupai Gorge, revealing that thrived in hyperarid landscapes one million years ago. Using biogeochemical analyses, precise chronometric dating, palaeoclimate simulations, biome modeling, fire history reconstructions, palaeobotanical studies, faunal assemblages, and archeological evidence, we reconstruct an environment dominated by semidesert shrubland.

Effect of Drying and Microwave-Assisted Extraction Parameters on Variety Koseret Essential Oil Yield.

Research Background: Green extraction technologies, such as microwave-assisted extraction, have been used to replace conventional methods of isolating essential oils from plants. In this study, the essential oil was extracted from the variety koseret using the advanced method of microwave-assisted hydrodistillation. The main objective was to investigate the effect of irradiation time, microwave power and particle size on the yield and chemical composition of the essential oil extracted from leaves dried in an oven at 50 °C and room temperature.

The trends of lung cancer burden in BRICS from 1990 to 2021 and its projection to 2035.

Background: Lung cancer has become the malignant tumor with the highest morbidity and mortality in the world. This study aims to analyze the burden of lung cancer and risk factors associated with lung cancer in the BRICS from 1990-2021 and to project the burden of lung cancer in the BRICS from 2021-2035.

Methods: The Global Burden of Disease (GBD) 2021 database was searched to collect the incidence, prevalence, mortality, disability-adjusted life years (DALYs), and risk factors of lung cancer in the BRICS.

Attitudes of nurses toward telenursing and influencing factors in resource-limited settings: Northwest Ethiopia 2022.

Background: The worldwide scarcity of nurses is a pressing concern, with the World Health Organization predicting a deficit of 5.9 million nurses globally by 2025. Notably, 89% of this shortage is expected to impact low- and middle-income countries.

Collagen deposition in lung parenchyma driven by depletion of interstitial Lyve-1 macrophages prevents cigarette smoke-induced emphysema and loss of airway function.

Introduction: Collagen is essential for maintaining lung structure and function and its remodeling has been associated with respiratory diseases including chronic obstructive pulmonary disease (COPD). However, the cellular mechanisms driving collagen remodeling and the functional implications of this process in the pathophysiology of pulmonary diseases remain poorly understood.

Methods: To address this question, we employed ; mice with specific depletion of Lyve-1 macrophages and assessed the content, types and organization of collagen in lung compartments at steady state and after chronic exposure to cigarette smoke (CS).

Prescribing practices of corticosteroids in outpatient dermatology department of Injibara General Hospital, north-West Ethiopia, 2024.

Background: Corticosteroids are among the most frequently prescribed drugs in the world because they are extremely effective for the relief of symptoms of many inflammatory and immune disorders and other conditions. Corticosteroids have been a mainstay of pharmacotherapy in dermatological practice.

Objective: This study aimed to assess prescribing practices of corticosteroids in outpatient dermatology department of Injibara General Hospital, North-West Ethiopia, 2024.

Mycodiversity in a micro-habitat: twelve species, including four new taxa, isolated from uredinia of coffee leaf rust, .

During surveys in the centres of origin of the coffee leaf rust (CLR), in Africa, as well as in its exotic range in Brazil, 23 isolates of the genus were obtained from uredinial pustules. Using a phylogenetic analysis of all isolates involving a combination of partial sequences of the internal transcribed spacer region of rDNA (ITS) and two gene regions: actin ( and translation elongation factor-1α (), 12 species were delimited; including four new species - , , and . GCPSR criteria were employed for species recognition, supported by morphological and cultural characters.

Dietary diversity and its associated factors among school children in conflict affected communities of southern Ethiopia.

Background: Globally, more than 815 million estimated people worldwide suffer from malnutrition or are unable to access enough food due to malnutrition. Conflict remains the single most fundamental factor contributing to chronic malnutrition in the conflict-affected areas. Developing a healthy and balanced dietary pattern is essential for school children because their habits in this period may last longer.

Effect of Amaranth-Containing Dietary Intervention in Improving Hemoglobin Concentration: A Systematic Review and Meta-Analysis.

Objective: Amaranth, a nutritious iron source, is known for treating anemia in young children and lactating mothers, but its effectiveness in reducing hemoglobin concentration needs further investigation. Therefore, this study aimed to summarize the effectiveness of amaranth-based food interventions in improving hemoglobin concentration.

Method: A randomized controlled trial and quasi-experimental study conducted since 2000 were searched in databases like PubMed, Scopus, Embase, Cochrane, AJOL, and Web of Science using prespecified keywords.

Socio-Economic Factors Influencing Intimate Partner Violence Among Adolescents and Young Women in Sub-Saharan Africa: A Scoping Review.

Objective: To summarize the evidence on how socio-economic status and intimate partner violence (IPV) are interrelated among adolescents and young women (AYW) in sub-Saharan Africa (SSA).

Methods: Online databases such as MEDLINE, Embase, PsycIFO, CINAHL, Cochrane Central, Sociological Abstracts, Web of Science, and the African Index Medicus were used to identify studies published between 2015 and 2022. The reporting procedure was the Preferred Reporting Item for Systematic Reviews and Meta-Analysis (PRISMA) as a checklist extension for the scoping review.

Chromium Removal Using a Basalt Rock Adsorbent in a Packed Bed Column for Efficient Environmental Protection.

The discharge of chromium(VI) into the environment is becoming a significant global concern. Despite the existence of numerous techniques for chromium(VI) removal, substantial challenges persist in effectively mitigating this issue. Therefore, this study investigates the feasibility of using low-cost basalt rock as an adsorbent for chromium(VI) removal.

Cu(II)-Catalyzed Synthesis of Pyrazolo[3,4-]pyridine Derivatives and Their Potential Antibacterial and Cytotoxic Activities with Molecular Docking, DFT Calculation, and SwissADME Analysis.

The present work focuses on a newly synthesized pyrazolo[3,4-]pyridine prepared by formal [3 + 3] cycloaddition using copper(II) acetylacetonate as the catalyst; efficient and effective mild reactions with high yields were obtained using this method. The synthesized compounds were identified by FT-IR, H and C NMR, and mass spectra (/) analyses. The compounds () were screened for several in vitro and in silico activities.

Socioeconomic and Environmental Impacts of Plantations in Ethiopia: An Evaluation of Benefits, Challenges, and Sustainable Practices.

was first introduced to Ethiopia in the late 19 century to address the scarcity of firewood and construction wood in the capital city. Since then, it has spread across the country and has become an important source of income for many households while also reducing the need for deforestation. Despite concerns raised by environmentalists about its eco-hydrological impact, the plantation has expanded to cover a vast area of the nation, including farmlands and mountainous regions.

Prevalence and predictors of self-medication practices among adult household members in Hosanna town, Hadiya zone, central Ethiopia.

Background: Self-medication is a global health concern with serious public health implications. Excessive and inappropriate self-medication practice can lead to recurrent infections and increased antibiotic resistance, which is a major problem impacting morbidity and mortality worldwide. Despite the significance of this issue, no single study has been conducted on self-medication practices in the study area, to the best of the researchers' knowledge.

Readiness to deliver quality curative care for under-five children at health posts in Ethiopia.

Background: The institutionalization of village health services with salaried community health workers has been established in Ethiopia for over a decade. However, there are serious concerns about the capacity of health posts to provide quality curative care for children under-five.Understanding the readiness of health posts is crucial for improving the care given to sick children.

Cognitive-Behavioral Intervention for Children With Hematological Cancer Receiving Chemotherapy: A Randomized Controlled Trial.

Objective: Cognitive-behavioral intervention (CBI) has shown positive effects in improving psychological and health-related outcomes in children with cancer. However, no evidence has been found in Ethiopia. This study aimed to evaluate the effects of CBI on anxiety, depression and quality of life (QoL) in Ethiopian children with hematological cancer receiving chemotherapy.

Association of gross domestic product with equitable access to childhood vaccines in 195 countries: a systematic review and meta-analysis.

Introduction: Gross domestic product (GDP) has been shown to affect government spending on various budget heads including healthcare and the purchase and distribution of vaccines. This vulnerable situation has been exacerbated by the COVID-19 pandemic which disrupted and exposed the fragile nature of equitable access to vaccines for childhood immunisation globally. A systematic review and meta-analysis to assess the association of country income status and GDP with vaccination coverage of vaccines for childhood immunisation and other major infectious diseases around the globe will inform global and national policy on equity in living standards and vaccine uptake.

Personalized medicine: An alternative for cancer treatment.

The incidence of cancer continues to increase worldwide, resulting in significant physical, emotional, and financial challenges for individuals, families, communities, and healthcare systems. Cancer is projected to be responsible for approximately 10 million deaths in 2020, accounting for one in six deaths globally. Prostate, colon, lung, and breast cancers are the most common types of cancer.

Incidence and determinants of mortality among patients with colorectal cancer in oncology centers of Amhara region, Ethiopia, 2024: multicenter retrospective follow up study.

Introduction: Colorectal cancer is a significant cause of mortality globally, with several factors impacting patient outcomes, including access to healthcare, early detection, and treatment. Despite this, the specific factors affecting incidence of death among colorectal cancer patients in the Amhara region have not been thoroughly investigated. Thus, this study seeks to assess incidence and determinants of mortality among colorectal cancer patients in Amhara Region oncology centers.

Bovine adenovirus prevalence and its role in bovine respiratory disease complex: a systematic review and meta-analysis.

Bovine adenoviruses (BAdVs) are major contributors to the bovine respiratory disease complex (BRDC). A systematic review and meta-analysis were carried out to explore the epidemiology of BAdV across diverse cattle populations using different detection methods. The study showed a higher BAdV prevalence of 0.

Exploring cultural intelligence and academic self-efficacy among teacher trainees in a context of intra-cultural diversity.

The purpose of this study was to determine Ethiopian teacher trainees' level of cultural intelligence and its association with demographic variables (gender and urban-rural dimension) within the context of intranational diversity. It was also aimed at determining the relationship between CQ and the academic self-efficacy of the participants. A quantitative approach was employed.