Treatment with anti-TNF-α for Crohn's disease is generally safe, but can cause skin issues like psoriasis, which may lead to discontinuation of the treatment.
Ustekinumab, a new treatment targeting interleukin 12/23, shows promise for Crohn's disease and psoriasis.
A case study illustrates a woman who developed psoriasis after two anti-TNF treatments but successfully managed both conditions with ustekinumab.