4,645 results match your criteria: "Eskisehir Osmangazi University; Eskisehir-Turkey.[Affiliation]"

Environmental pollution is a problem that affects food safety throughout the world. In this study, a health risk assessment of possible toxic metal and aflatoxin contamination in homemade and industrial noodles produced in Türkiye was carried out. Samples were taken from 67 kinds of homemade and five kinds of industrial noodles from different cities.

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Genome-wide analysis of cellulose synthase (CesA) and cellulose synthase-like (Csl) proteins in L.

PeerJ

December 2024

Agricultural Biotechnology Laboratory, Department of Plant Science and Landscape Architecture, University of Connecticut, Storrs, CT, United States of America.

The cellulose and hemicellulose components of plant cell walls are synthesized by the cellulose synthase (CESA) and cellulose synthase-like (CSL) gene families and regulated in response to growth, development, and environmental stimuli. In this study, a total of 29 CESA/CSL family members were identified in and were grouped into seven subfamilies (CESA, CSLA, CSLB, CSLC, CSLD, CSLE and CSLG) according to phylogenetic relationships. The CESA/CESA proteins of were closely related phylogenetically to the members of the subfamily of other species.

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The Effect of Olfactory Stimulation on Growth Parameters in Newborn Infants: A Systematic Review.

Breastfeed Med

December 2024

Faculty of Health Sciences, Department of Child Health and Disease Nursing, Eskisehir Osmangazi University, Eskisehir, Turkey.

Olfactory stimulation can be used for many purposes, such as providing comfort, improving sleep, and reducing pain in newborns. However, there are only a few studies in the literature examining the effect of olfactory stimulation on newborn growth. The aim of this study was to evaluate the effect of olfactory stimulation on growth parameters of newborns.

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Objective: Factors such as the risk of the spread of infectious diseases, global health crises, and disasters are among the major health and security challenges facing societies. Informed protective measures and effective risk awareness are necessary to cope with these challenges. As young adults, university students represent a significant segment of society, making studies conducted on this group critical for implementing effective measures against infectious disease risks.

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Objectives: A useful way to prepare the public for disasters is to teach them where to get information. The purpose of this study is to evaluate the readability and appropriateness of the content of websites prepared for the public on disaster preparedness.

Methods: In September-October 2022, we evaluated 95 disaster preparedness websites (intended for the public) using the Ateşman Readability Index, JAMA criteria, DISCERN, and a new researcher-created content comparison form.

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Aqueous zinc-ion batteries (ZIBs) are gaining attraction for large-scale energy storage systems due to their high safety, significant capacity, cost-effectiveness, and environmental friendliness. On the other hand, the development of aqueous ZIBs is restricted by the limited practical application of zinc (Zn) because of the high reactivity of Zn in aqueous electrolytes, which results in the severe dendrite growth and parasitic side reactions such as hydrogen evolution reaction (HER). In this study, heteroatom-doped carbon porous surface modification by laser-assisted carbonization of copper (Cu) doped polyaniline (PANI) is designed and fabricated on top of the Zn metal anode (c-Cu-PANI/Zn).

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The postpartum period is a well-defined risk factor for cerebral venous sinus thrombosis (CVST). However, it is unclear which patients are at risk for CVST in the postpartum period. Thus, determining some CVST risk factors in postpartum patients may be useful for preventing the disorder in this population.

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Sustainability in beekeeping depends on identifying the factors affecting honey and beeswax yields (HY and BWY) - key products - and accurately predicting these yields. Therefore, this study aimed to predict HY and BWY using a classification and regression tree (CART), eXtreme Gradient Boosting (XGBoost) and Random Forest (RF) algorithms, and thermal image processing in Apis mellifera. In this study, 13 colonies of 6 different breeds raised in 10-frame Langstroth hives were used.

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Article Synopsis
  • The study evaluates a new meningococcal vaccine (MenABCWY) that combines components of the existing MenB vaccine (4CMenB) and the MenACWY vaccine, aiming to provide broad immunization against various meningococcal strains and ease vaccination schedules.
  • Conducted as a phase 3 randomized trial across multiple countries, healthy participants aged 10-25 were assigned to receive different vaccine schedules to assess safety, immune response, and consistency of vaccine lots.
  • The trial primarily focused on the immune response to MenB strains, comparing MenABCWY's effectiveness to 4CMenB and evaluating the consistency of immune responses among different production lots of the vaccines.
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Background And Aim: Diabetes has been shown in last decades to be associated with a significantly higher mortality among patients with ST-segment elevation myocardial infarction (STEMI) treated with primary PCI (PPCI). Therefore, the aim of current study was to evaluate the impact of diabetes on times delays, reperfusion and mortality in a contemporary STEMI population undergoing PPCI, including treatment during the COVID pandemic.

Methods And Results: The ISACS-STEMI COVID-19 is a large-scale retrospective multicenter registry involving PPCI centers from Europe, Latin America, South-East Asia and North-Africa, including patients treated from 1st of March until June 30, 2019 and 2020.

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  • Autism spectrum disorders (ASDs) are neurodevelopmental conditions marked by social skill deficits and abnormal sensory responses, with an imbalance of excitation and inhibition in the brain being a crucial factor.
  • This study examined the levels of key neurotransmitters (GABA, glutamate, and serotonin) in the thalamus of rats induced with ASD using valproic acid (VPA) during pregnancy.
  • Results showed that ASD rats had higher serotonin levels, altered thalamic volumes, and fewer thalamic neurons and glia compared to the control group, suggesting a disrupted neurotransmitter balance in the thalamus related to ASD.
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Earthquakes may play a role in the development of several psychological distresses or psychopathologies. Nevertheless, protective factors such as positive emotions, psychological flexibility, and coping mechanisms may be helpful for earthquake survivors in coping. On the other hand, the role of both positive and negative emotions of earthquake survivors in psychological flexibility and coping remains elusive.

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  • PIWI-Interacting RNAs (piRNAs) are small non-coding RNAs that help regulate gene expression by silencing transposons and degrading mRNA, which is critical for controlling cancer cell behavior.
  • The study focused on inhibiting two specific piRNAs (piR-651 and piR-823) in triple-negative breast cancer cells (MDA-MB-231) and assessing the impact on healthy human vascular cells (HUVEC).
  • Findings showed that blocking piR-651 and piR-823 significantly reduced cancer cell motility and invasion, while having minimal effects on healthy cells, indicating their potential for use in targeted cancer therapies.
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Decoding Drug Discovery: Exploring A-to-Z In Silico Methods for Beginners.

Appl Biochem Biotechnol

December 2024

Department of Chemistry, Faculty of Sciences and Arts, Eskisehir Osmangazi University, Eskişehir, 26040, Turkey.

The drug development process is a critical challenge in the pharmaceutical industry due to its time-consuming nature and the need to discover new drug potentials to address various ailments. The initial step in drug development, drug target identification, often consumes considerable time. While valid, traditional methods such as in vivo and in vitro approaches are limited in their ability to analyze vast amounts of data efficiently, leading to wasteful outcomes.

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  • Acute kidney injury (AKI) significantly impacts mortality and morbidity in critically ill patients, and the serum uric acid-to-albumin ratio may serve as a prognostic marker for assessing patient outcomes.
  • A study involving over 1,000 ICU patients found that the uric acid-to-albumin ratio effectively predicted 28-day mortality, with specific ratios indicating varied levels of prediction accuracy for both AKI and non-AKI groups.
  • The findings suggest that utilizing this affordable biomarker in clinical settings could improve management strategies and better predict outcomes for critically ill patients.
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MicroRNA profiling in human cartilage is necessary for chondrogenesis. The study aimed to compare microRNA 127-5p (miR-127-5p) and TGF-β signaling pathway gene expressions of human adipose tissue-derived mesenchymal stem cells (hAT-MSCs) and synovial fluid-derived stem cells (hSF-MSCs) after induced chondrogenesis. MSCs induced into chondrogenic differentiation.

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  • Dual antiplatelet therapy (DAPT) is essential for managing acute and chronic coronary syndromes, helping to lower mortality rates and prevent further complications.
  • A study followed 1500 patients on a specific fixed-dose DAPT (ASA + clopidogrel) to evaluate its effectiveness and safety, primarily focusing on hospitalization and bleeding risks.
  • Results indicated that the fixed-dose combination therapy was effective, with low rates of hospitalization for cardiovascular issues and minimal bleeding complications in appropriately selected patients.
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Background: Manually creating multiple-choice questions (MCQ) is inefficient. Automatic item generation (AIG) offers a scalable solution, with two main approaches: template-based and non-template-based (AI-driven). Template-based AIG ensures accuracy but requires significant expert input to develop templates.

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Background: Bipolar disorder (BD) is a serious mood disorder, notable for its morbidity and prevalence. It ranks among the top 10 diseases globally in terms of functional impairment among affected individuals. Studies investigating neurobiological processes in the development of BD also aim to identify biological markers.

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  • Mitochondria play a crucial role in early embryo development by providing energy through mitochondrial DNA, particularly during the transition from oocyte to embryo.
  • This study compared the expression of specific genes related to mitophagy and apoptosis in the culture fluids of embryos from different patient groups, including those with polycystic ovary syndrome (PCOS) and varying ovarian reserves.
  • The findings suggest that analyzing the gene expressions in embryo culture fluids can offer insights into mitochondrial dysfunction and cellular health in female infertility without invasive procedures.
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  • The study aims to differentiate complicated acute appendicitis (CAA) from uncomplicated acute appendicitis (UCAA) by using serum sodium levels and the neutrophil-to-lymphocyte ratio (NLR) as potential diagnostic markers.
  • A total of 3,066 patients with histologically confirmed acute appendicitis were analyzed, revealing that 11.3% had CAA, and there was a statistically significant difference in mean ages between the two groups.
  • The findings indicated that while serum sodium is a stronger predictor for CAA than NLR, combining both metrics can improve identification of high-risk patients for timely surgical intervention.
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Purpose: This study aimed to develop the "Sudden Infant Death Syndrome Awareness Scale-Mother Form" (SIDSAS-MF) and assess its psychometric properties.

Design And Methods: The methodological study involved mothers (n = 450) with infants aged 0-12 months. Data were collected using a socio-demographic information form and the draft of the SIDSAS-MF.

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