3,297 results match your criteria: "Erythroderma Generalized Exfoliative Dermatitis"
[Erythroderma Complicated With Kaposi Varicelliform Eruption:Report of One Case].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
October 2024
Department of Dermatology, Second Hospital of Shanxi Medical University,Taiyuan 030001,China.
Kaposi varicelliform eruption (KVE) refers to an infectious skin disease that occurs after infection with herpes simplex virus,Coxsackie virus,or other viruses on the basis of preexisting skin diseases,commonly observed in the patients with eczema.It is rare for the patients with erythroderma to be complicated with KVE,and symptoms are often atypical,which pose a challenge to the diagnosis and treatment.This article reports a case of erythroderma complicated with KVE,aiming to raise awareness of clinicians in treating this disease.
View Article and Find Full Text PDFAdverse events associated with carbamazepine: a pharmacovigilance study using the FDA Adverse Event Reporting System.
Expert Opin Drug Saf
October 2024
Department of Acupuncture and Moxibustion, Foshan Hospital of Traditional Chinese Medicine, Foshan, Guangdong, China.
Article Synopsis
- Carbamazepine (CBZ) is a widely used medication for epilepsy, but its side effects can complicate treatment, prompting the need for more in-depth studies on adverse drug reactions (ADRs).
- The research utilized the FDA Adverse Event Reporting System (FAERS) database to analyze CBZ-related ADRs, employing various risk detection methods while considering patient demographics like sex and age.
- Findings revealed that common ADRs included hereditary disorders and infections, with notable risks such as bone metabolism issues and ocular problems that are often underreported, highlighting the need for better monitoring and alternative treatment options for high-risk patients.
Thymoma-Associated Multiorgan Autoimmunity (TAMA) Presenting as a Graft Versus Host Disease-Like Erythroderma.
J Cutan Pathol
January 2025
Department of Dermatology, West Virginia University School of Medicine, Morgantown, West Virginia, USA.
Article Synopsis
Erythroderma Following Pfizer-BioNTech COVID-19 Vaccination in a Patient With Atopic Dermatitis: A Case Report.
Cureus
September 2024
Dermatology, Imperial Dermatology, Hollywood, USA.
Article Synopsis
- Cutaneous reactions to mRNA COVID-19 vaccines can include various skin issues, especially in patients with existing dermatologic diseases.
- A case report details a 73-year-old man with atopic dermatitis who developed severe erythroderma after each Pfizer-BioNTech vaccine dose, which covered 95% of his body.
- Quick identification and treatment of erythroderma are crucial to prevent serious complications, highlighting the need for awareness of this reaction in susceptible individuals.
A case of revertant mosaic-like normal-looking spots in a patient with erythroderma with IL36RN and CARD14 heterozygous mutations.
J Dermatol
December 2024
Department of Dermatology, Gifu University Graduate School of Medicine, Gifu, Japan.
Article Synopsis
- An 89-year-old woman from Japan had a skin condition that made her skin very red and scaly.
- Doctors found some unusual changes in her skin cells and discovered she had mutations in two specific genes (IL36RN and CARD14).
- She later developed small, round spots on her skin that looked normal, but tests showed these spots might be different from her red, scaly skin despite having the same gene mutations.
A real-world pharmacovigilance analysis of eslicarbazepine acetate using the FDA adverse events reporting system (FAERS) database from 2013 (Q4) to 2024 (Q1).
Front Pharmacol
September 2024
Department of Pharmacy, The 305 Hospital of PLA, Beijing, China.
Article Synopsis
- The study investigates adverse events (AEs) associated with eslicarbazepine acetate (ESL), a medication approved in 2013 for partial-onset seizures, using data from the FDA Adverse Event Reporting System (FAERS).
- It employs various statistical methods to identify significant AE signals and examines demographic factors like gender and age related to these events.
- The analysis revealed 5,719 AE reports, with notable issues related to nervous system disorders occurring mostly within the first month of treatment, resulting in 86 significant positive signals.
Deciphering the Etiologies of Adult Erythroderma: An Updated Guide to Presentations, Diagnostic Tools, Pathophysiologies, and Treatments.
Am J Clin Dermatol
November 2024
Department of Dermatology, Northwestern University Feinberg School of Medicine, 676 N Saint Clair, Arkes 1600, Chicago, IL, 60611, USA.
Article Synopsis
- Erythroderma is a serious inflammatory skin condition known for widespread redness and can include symptoms like peeling, pus formation, and blisters, often leading to significant health risks.
- Identifying the root cause of erythroderma can be difficult, which complicates treatment and contributes to a generally poor outlook for affected individuals.
- The review outlines the appearance, causes, diagnosis, and treatment options for erythroderma, and highlights the differences between similar skin conditions, along with new research aimed at improving future diagnosis and care.
Pustular Erythroderma in an Infant.
JAMA Dermatol
October 2024
Division of Dermatology, Department of Pediatrics, Universite de Montreal, Montreal, Quebec, Canada.
Article Synopsis
- Erythroderma is a severe skin condition causing widespread redness and scaling, often linked with inflammatory conditions like psoriasis, and affects over 90% of the body's surface area.
- * A case report describes a 68-year-old man with erythrodermic psoriasis who faced complications including sepsis, endocarditis, and a mycotic aneurysm after failing multiple treatments.
- * The study highlights the urgent need for better treatment guidelines for psoriatic erythroderma due to high mortality risks from extensive skin damage and infections.
Hydrochlorothiazide-Induced Exfoliative Rash and Sepsis.
Cureus
July 2024
Internal Medicine, Garnet Health Medical Center, Middletown, USA.
Article Synopsis
- Hydrochlorothiazide is a common diuretic used to manage conditions like high blood pressure, fluid retention from heart issues, and certain kidney disorders.
- Diuretics increase urine output and can lead to side effects, with major concerns being low blood volume and electrolyte imbalances, alongside rarer issues like skin reactions.
- The case involves an 86-year-old man who experienced lightheadedness and a worsening rash after starting hydrochlorothiazide, prompting an emergency room visit.
Erythroderma-like crusted scabies in an immunocompetent patient after systemical corticosteroids.
Skin Res Technol
July 2024
Shanxi Medical University, Taiyuan, Shanxi, China.
Pulmonary manifestation of VEXAS syndrome.
BMJ Case Rep
July 2024
Pneumology Department, University Hospital Zurich, Zurich, Switzerland
Article Synopsis
- * Although the patient responded well to immunosuppression, his symptoms returned when the corticosteroid dosage was reduced, leading to a lengthy diagnostic process.
- * Ultimately, it took almost a year to correctly diagnose him with VEXAS syndrome, emphasizing the difficulties in recognizing such rare conditions and the necessity for greater awareness within the medical community.
Netherton Syndrome in Thai Children: A Report of Two Cases With a Literature Review.
Cureus
June 2024
Division of Allergy, Immunology, and Rheumatology, Department of Pediatrics, Queen Sirikit National Institute of Child Health, Bangkok, THA.
Article Synopsis
- Netherton syndrome (NS) is a rare genetic disorder that presents with three main features: skin conditions, hair abnormalities, and allergic tendencies.
- The cases discussed involved patients with serious skin issues, frequent infections, and allergy-related problems, where microscopic hair examination showed specific hair defects.
- Genetic testing revealed harmful mutations in the SPINK5 gene, and better skincare and nutrition could enhance the patients' overall well-being.
A novel MALT1 variant in an Egyptian patient presenting with exfoliative dermatitis: a case-based review.
Immunol Res
October 2024
Department of Pediatrics, Faculty of Medicine, Cairo University, Cairo, Egypt.
Article Synopsis
- Recent studies show that errors in the CARD11-BCL10-MALT1 (CBM) signalosome can cause severe immunodeficiencies, presenting with various symptoms including frequent infections and skin issues.
- A case study of an Egyptian patient with a mutation in the MALT1 gene revealed severe skin rashes, diarrhea, pneumonia, and abnormal immune markers, indicating a diagnosis of immunodeficiency-12 (IMD12).
- The research emphasizes the importance of molecular diagnosis to differentiate between similar immunodeficiencies, as better understanding can facilitate early treatment options like stem cell transplantation, improving patient outcomes.
Risk factors of bloodstream infection in erythroderma from atopic dermatitis, psoriasis, and drug reactions: a retrospective observational cohort study.
PeerJ
July 2024
Department of Dermatology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Article Synopsis
- A study examined the occurrence of bloodstream infections (BSI) in patients with erythroderma, finding BSI in 7.80% of cases, more commonly in drug reactions (17.14%) than in atopic dermatitis (7.14%) or psoriasis (2.00%).
- Key risk factors for developing BSI included abnormal body temperature, chilling sensations, kidney disease, and certain laboratory markers like high CRP and low albumin levels.
- The research emphasizes the need for heightened awareness and monitoring for BSI in erythroderma patients, especially those with identified risk factors.
Clinical Efficacy and Safety of Interleukin-17 Inhibitors in Treating Patients with Erythrodermic Psoriasis: A Retrospective Cohort, Three-Center Study.
Am J Clin Dermatol
September 2024
Department of Dermatology, The Eighth Affiliated Hospital, Sun Yat-Sen University, 3025 Shennan Road Central, Shenzhen, 518033, China.
Preoperative management and postoperative complications in 9 dogs undergoing surgical treatment of thymic-associated myasthenia gravis.
Can Vet J
July 2024
Department of Clinical Sciences, NC State University College of Veterinary Medicine, 1060 William Moore Drive, Raleigh, North Carolina 27607, USA (Saylor, Scharf); Department of Clinical Studies, University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1 (Oblak, McKenna); Department of Veterinary Clinical Sciences, Purdue University College of Veterinary Medicine, 625 Harrison Street, West Lafayette, Indiana 47907, USA (Risselada); Department of Small Animal Clinical Sciences, Texas A&M University College of Veterinary Medicine & Biomedical Sciences, 4474 Raymond Stotzer, College Station, Texas 77843, USA (Thieman).
Article Synopsis
- Paraneoplastic syndromes in dogs and cats linked to thymoma include diseases like myasthenia gravis (MG), which is the most frequently reported condition associated with thymic tumors in dogs.
- The study reviewed medical records of nine dogs treated surgically for thymic epithelial tumors and analyzed their preoperative care, postoperative issues, and overall outcomes.
- Results showed that while three dogs faced immediate complications, six survived surgery, with varying degrees of recovery in MG symptoms, indicating a significant risk of complications during surgery for these conditions.
Erythroderma in Adult-Onset Still's Disease Alleviated After Tocilizumab Therapy: A Case Report.
Cureus
May 2024
Department of Pathology, Peking University International Hospital, Beijing, CHN.
Erythroderma, also known as exfoliative dermatitis, is a rarely reported atypical cutaneous manifestation of adult-onset Still's disease (AOSD). We present the case of erythroderma in association with AOSD that was steroid dependent and responded to tocilizumab therapy. Skin rash, pruritis, and related laboratory findings were significantly improved upon the addition of tocilizumab, while prednisolone was successfully tapered to an ever-lowest maintenance level.
View Article and Find Full Text PDFLong-term Efficacy of Dupilumab in Papulo-erythroderma of Ofuji.
Acta Derm Venereol
June 2024
Department of Dermatology, Hôpital Robert-Debré, Reims, France;University of Reims Champagne-Ardenne (URCA), EA7509 IRMAIC, Reims, France.
Erythrodermic Pityriasis Rubra Pilaris Following COVID-19 Vaccination.
Cutis
April 2024
Department of Dermatology, Cairo University-Faculty of Medicine, Egypt.
A rare incidence of severe dermatological toxicities triggered by concomitant administration of all-trans retinoic acid and triazole antifungal in patients with acute promyelocytic leukemia: a case series and review of the literature.
J Med Case Rep
May 2024
Section of Malignant Haematology, National Institute of Blood Disease and Bone Marrow Transplantation, Karachi, Pakistan.
Background: All-trans retinoic acid (ATRA) is an indispensable part of the treatment of acute promyelocytic leukemia (APL). Although, mild cutaneous toxicities like mucocutaneous xerosis, rash, and pruritus are well reported, ATRA associated severe dermatological toxicities are extremely rare. ATRA is primary metabolized by cytochrome P450 (CYP450) enzyme system, and triazole antifungals are notorious for their strong inhibitory effect on CYP450.
View Article and Find Full Text PDFExploration of circulating metabolic signature of erythrodermic psoriasis based on LC-MS metabolomics.
Exp Dermatol
May 2024
Department of Dermatology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, Beijing, China.
Article Synopsis
- Erythrodermic psoriasis (EP) is a rare and serious disease, with unclear causes, prompting a study to analyze metabolic changes in affected patients compared to healthy individuals.
- An analysis of serum samples from EP patients identified 98 significantly altered metabolites, including lower levels of certain amino acids and higher levels of others, suggesting disruptions in amino acid and glycerophospholipid metabolism.
- The findings highlight that specific metabolic changes, particularly low levels of L-tryptophan, could help understand EP's development and may lead to new treatment strategies.
Early Gestational Diabetes Mellitus: An Update.
J Assoc Physicians India
March 2024
Consultant Obstetrician, BG Clinic & Maternity Nursing Home, Delhi, India.
Article Synopsis
- Erythroderma is a serious skin condition characterized by widespread redness and scaling affecting more than 90% of the body's surface area.
- It can be caused by a variety of conditions, including psoriasis, atopic dermatitis, and drug reactions, but is rarely linked to fungal infections like dermatophytosis.
- This text discusses a specific case where erythroderma developed as a result of extensive dermatophytosis infection.
Inappropriate Use of Steroids in Superficial Dermatophytosis: An Uncommon Case of Erythroderma.
J Assoc Physicians India
March 2024
Senior Resident, Department of Dermatology, Rabindranath Tagore Medical College, Udaipur, Rajasthan, India.
Article Synopsis
- Erythroderma is a serious skin condition characterized by widespread redness and scaling affecting almost the entire body surface.
- It can result from various causes, including psoriasis, atopic dermatitis, and certain types of skin infections, but cases due to dermatophytosis (fungal infections) are uncommon.
- This text discusses a specific case where erythroderma occurred as a secondary effect of extensive dermatophytosis.
Erythroderma: clinical and etiological study of 88 cases seen in a tertiary hospital over 25 years.
An Bras Dermatol
June 2024
Department of Internal Medicine, Universidade Estadual de Londrina, Londrina, PR, Brazil.