75 results match your criteria: "Erythema Induratum Nodular Vasculitis"
Nodular Vasculitis: Retrospective Study of an Uncommon Disease in a Non-Tuberculosis Endemic Country with Focus on Treatment Modalities and Efficacy.
Dermatology
November 2024
Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.
Introduction: Nodular vasculitis (NV) is a rare form of panniculitis primarily affecting middle-aged females, presenting as painful, sometimes ulcerated nodules on the dorsal lower legs. Erythema induratum of Bazin (EIB) is a form of NV and is considered a manifestation of cutaneous tuberculin hypersensitivity. This retrospective study aims to analyze demographics, clinicopathological findings, laboratory results, and treatment outcomes of NV in a non-TB endemic country.
View Article and Find Full Text PDFShould antituberculosis treatment be prescribed in erythema induratum? A case-control and incidence correlation study in Taiwan, 2001-2020.
Clin Exp Dermatol
July 2024
Department of Dermatology, Mackay Memorial Hospital, Taipei, Taiwan.
Article Synopsis
- Erythema induratum (EI) is linked to tuberculosis (TB), but recent data from Taiwan shows a low detection rate of Mycobacterium tuberculosis in EI cases.
- A study examined the relationship between EI cases and the annual incidence of TB in Taiwan over 20 years, using medical histories and PCR tests.
- The findings revealed that most EI cases are not related to TB infection, indicating that the condition can improve without the need for anti-TB treatment.
Nodular vasculitis (erythema induratum) associated with systemic minocycline.
Australas J Dermatol
March 2024
Department of Dermatology, Mater Dei Hospital, Msida, Malta.
Article Synopsis
- A 29-year-old woman experienced painful swelling and nodules on her legs after taking minocycline for acne for 3 years.
- Biochemical tests revealed liver issues and positive antibodies indicative of an autoimmune response, leading to a skin biopsy that confirmed nodular vasculitis.
- After stopping minocycline, her symptoms and liver function improved within 3 months, prompting caution about long-term minocycline use due to its potential to cause nodular vasculitis.
[Translated article] Atypical Nodular Vasculitis-A Diagnostic Clue in Metastatic Melanoma.
Actas Dermosifiliogr
December 2022
Servicio de Dermatología, Spain.
Etiologic dilemma and challenges of management of nodular vasculitis in tertiary health-care facility: A case report.
Niger J Clin Pract
September 2022
Department of Medical Microbiology, College of Medicine University of Nigeria/University of Nigeria Teaching Hospital, Ituku Ozalla, Enugu, Nigeria.
Article Synopsis
- Nodular vasculitis is an uncommon inflammatory skin condition that causes painful red nodules primarily on the legs, particularly affecting the calves and shins.
- A 17-year-old girl showed symptoms including a long-term cough, recurrent fever, and ulcerated nodules on her legs, alongside significant swelling and other systemic signs.
- Despite negative tests for HIV and tuberculosis and a biopsy revealing severe tissue damage and inflammation, her condition worsened after a brief response to antibiotics, ultimately leading to her death from sepsis.
Tuberculoid Leprosy Masquerading as Erythema Induratum.
HCA Healthc J Med
April 2021
Lotus Dermatology, Brooksville, FL.
Article Synopsis
- Erythema Induratum (EI) is a rare skin condition affecting the subcutaneous fat, diagnosed in a 70-year-old woman who presented with a painful, red rash.
- The condition is associated with various factors and typically appears as nodules on the lower legs, often requiring a biopsy for accurate identification.
- In this case, the patient's rash was linked to tuberculoid leprosy, and treatment involved both managing EI with NSAIDs and potassium iodide, and treating leprosy with dapsone and rifampin, highlighting the need for thorough clinical evaluation.
Program-wide review and follow-up of erythema Induratum of Bazin and tuberculosis-associated ocular inflammation management in a TB low-incidence setting: need for improved treatment candidate selection, therapy standardization, and care collaboration.
BMC Infect Dis
January 2019
Department of Medicine, University of Calgary, Alberta, Canada.
Article Synopsis
- Erythema induratum of Bazin (EIB) and Tuberculosis-Associated Ocular Inflammation (TB-AOI) are rare health problems connected to TB, and there aren’t clear ways to diagnose or treat them.
- A study looked at 21 EIB and 20 TB-AOI cases over 11 years, focusing on patients who got treatment and found that most were women from countries with lots of TB.
- While some patients got better after treatment, the results were better for EIB cases compared to TB-AOI, showing that doctors need better ways to choose treatments and work together across specialities.
Nodular vasculitis associated with lung adenocarcinoma.
An Bras Dermatol
February 2019
Department of Dermatology and Venereology, Hospital Santo António dos Capuchos, Centro Hospitalar de Lisboa Central, Lisbon, Portugal.
Article Synopsis
- * There has been only one previous instance of nodular vasculitis linked to metastatic colon cancer.
- * This report presents a unique case where nodular vasculitis is the first sign of lung adenocarcinoma, marking a novel association between the two.
Use of QuantiFERON-TB Gold to determine the aetiology of idiopathic erythema induratum: A case report.
SAGE Open Med Case Rep
October 2018
Toronto Regional Dermatology and Wound Healing Clinic, Mississauga, ON, Canada.
Article Synopsis
- - Erythema induratum, a rare skin condition linked to lobular panniculitis and vasculitis, is primarily triggered by hypersensitivity reactions but can have other causes.
- - A case study details a 73-year-old male with painful red nodules on his legs who was misdiagnosed with idiopathic erythema induratum after ineffective treatment with isoniazid for 9 months.
- - After testing positive for tuberculosis using the QuantiFERON-TB Gold assay, the patient was successfully treated with a combination of medications, demonstrating the importance of accurate testing and a multi-drug strategy over just isoniazid.
Nodular Vasculitis in a Patient With Crohn's Disease on Vedolizumab.
Am J Dermatopathol
March 2018
Department of Dermatology, University of California, Irvine, Irvine, CA.
Erythema induratum (EI), or nodular vasculitis (NV), is a type of panniculitis that is often associated with vasculitis affecting various-sized veins, venules, and arteries in reaction to various causative factors. Historically, EI was highly linked to tuberculosis, but in 1946, Montgomery first proposed the term NV to describe cases of EI not associated with tuberculosis. Only 2 reports of NV associated with inflammatory bowel disease have been reported in the literature.
View Article and Find Full Text PDFErythema induratum (nodular vasculitis) associated with Takayasu arteritis.
Eur J Dermatol
August 2017
Department of Dermatology, Shiga University of Medical Science, Setatsukinowa, Otsu, Shiga 520-2192, Japan.
Treatment of nodular vasculitis with colchicine.
Australas J Dermatol
August 2017
Department of Dermatology, St Vincent's Hospital, Melbourne, Victoria, Australia.
Article Synopsis
- * Three patients with NV who didn't respond to other treatments got better when they were given a medicine called colchicine.
- * Colchicine helped reduce symptoms and was safer than using steroids, but stopping it caused one patient’s symptoms to come back.
Panniculitis caused by Mycobacterium monacense mimicking erythema induratum: a case in Ecuador.
New Microbes New Infect
March 2016
Hospital Vozandes, Ecuador; Unidad de Investigaciones en Biomedicina, Zurita & Zurita Laboratorios, Ecuador; Facultad de Medicina, Pontificia Universidad Católica del Ecuador, Ecuador.
Article Synopsis
- A young woman in Ecuador was found to have chronic nodular vasculitis caused by a newly identified species called M. monacense.
- This case marks the first time M. monacense has been isolated in Ecuador.
- The identification of the species was accomplished using both traditional and molecular methods.
Nodular Vasculitis That Developed during Etanercept (Enbrel) Treatment in a Patient with Psoriasis.
Ann Dermatol
October 2015
Department of Dermatology, Chungnam National University School of Medicine, Daejeon, Korea.
Article Synopsis
- A 28-year-old man with long-standing psoriasis developed nodular lesions on his leg after starting etanercept, a treatment for psoriasis, one year prior.
- After a biopsy confirmed nodular vasculitis and tests ruled out tuberculosis, the patient stopped etanercept, leading to gradual improvement and no recurrence during a six-month follow-up.
A Case of Tuberculous Granulomatous Panniculitis without Vasculitis.
Case Rep Dermatol
September 2015
Department of Internal Medicine, Rehabilitation and Geriatrics, Geneva, Switzerland.
Article Synopsis
- An 87-year-old woman with B-cell chronic lymphocytic leukaemia developed skin lesions after starting chemotherapy, presenting initially as erythematous plaques.
- A biopsy revealed granulomatous panniculitis without caseation necrosis or vasculitis, and tests confirmed the presence of Mycobacterium tuberculosis in the skin.
- The case highlights the importance of combining clinical observations, histopathological findings, and microbiological analysis for diagnosing cutaneous tuberculosis, especially in immunocompromised patients.
Article Synopsis
- - The interferon-γ release assay (IGRA) is a new way to check if someone was exposed to tuberculosis (TB) and can be better than the old skin test, especially for people who might have gotten a vaccine called BCG in the past.
- - In a study of four patients with a skin condition linked to TB, the IGRA test helped show if their issues were related to TB or not.
- - The results showed that two patients had a connection to TB, while the other two did not but responded well to different treatments, suggesting that using the IGRA test could help doctors decide the best treatment for patients.
Panniculitis with vasculitis.
G Ital Dermatol Venereol
August 2013
Anatomic Pathology Unit Gaetano Rummo General Hospital, Benevento, Italy -
Article Synopsis
- Panniculitides include various conditions affecting the subcutaneous tissue, with a focus on identifying vasculitis through histopathology.
- The main differential diagnoses are polyarteritis nodosa (PAN), nodular vasculitis (NV), and Bazin's erythema induratum (EI), with PAN requiring long-term monitoring due to potential systemic progression.
- NV and EI are the most common types of lobular panniculitis with vasculitis, and it's important to differentiate them based on NV positive skin test results equating to EI, while other rare types are linked to systemic conditions like infections or autoimmune disorders.
How to make a specific diagnosis of panniculitis on clinical grounds alone: an integrated pathway of general criteria and specific findings.
G Ital Dermatol Venereol
August 2013
Article Synopsis
- This paper talks about how doctors diagnose a skin problem called panniculitis by looking closely at the patient's symptoms, history, and lab results.
- The goal is to help dermatologists make a specific diagnosis instead of just taking a skin sample and waiting for results.
- It also discusses different kinds of panniculitis, like Erythema Nodosum and Lupus Panniculitis, and explains what signs and symptoms doctors should pay attention to for a better diagnosis.
Erythema induratum of Bazin associated with Addison's disease: first description.
Sao Paulo Med J
September 2013
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, Brazil.
Article Synopsis
- Erythema induratum of Bazin (EIB) is a skin condition linked to tuberculosis, characterized by recurring painful nodules, and it can be confused with other diseases like nodular vasculitis and erythema nodosum.
- A case study reported a woman who developed Addison's disease while undergoing treatment with anti-tuberculosis drugs, showing improvement with glucocorticoid replacement therapy.
- This case is significant as it highlights the potential link between EIB and Addison's disease, emphasizing the role of tuberculosis in causing Addison's disease.
Application of the QuantiFERON®-TB Gold test in erythema induratum.
J Dermatolog Treat
June 2014
Department of Dermatology, College of Medicine, Soonchunhyang University, Seoul , South Korea.
Article Synopsis
- A 33-year-old woman's persistent ulcerative nodules led to a TB suspicion after initial conservative treatment failed, despite negative conventional tests for TB.
- The positive QuantiFERON®-TB Gold test confirmed latent TB infection, and the patient was successfully treated with antituberculosis therapy, resolving her skin lesions.
Clofazimine-induced enteropathy in treatment-resistant nodular vasculitis.
Australas J Dermatol
May 2012
Department of Dermatology, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.
Article Synopsis
- * The introduction of oral clofazimine at 300 mg daily allowed for a significant reduction in prednisolone dosage to 22.5 mg and completely suppressed the disease activity.
- * However, after nearly two years of successful treatment, the patient experienced clofazimine-induced enteropathy, leading to the discontinuation of the drug which resulted in a flare of the vasculitis, highlighting the need for caution and awareness of potential side effects when using clofazimine.
Chlamydophila pneumoniae Infection Induced Nodular Vasculitis.
Case Rep Dermatol
September 2011
Department of Dermatology, Kitasato University School of Medicine, Sagamihara, Japan.
Article Synopsis
- - A 48-year-old male with Chlamydophila pneumoniae infection developed nodular vasculitis, which is inflammation of the blood vessels causing skin nodules.
- - His respiratory symptoms preceded the development of the skin condition, linking the two health issues.
- - The diagnosis was confirmed through blood tests, highlighting the need to consider Chlamydophila pneumoniae as a possible cause of nodular vasculitis, especially since this infection is common and often asymptomatic.
Erythema induratum (nodular vasculitis) associated with Crohn's disease: a rare type of metastatic Crohn's disease.
Am J Dermatopathol
May 2012
Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan.
Article Synopsis
- A 54-year-old woman with a history of Crohn's disease (CD) developed erythema induratum/nodular vasculitis (EI/NV), presenting as painful red nodules on her legs.
- The skin biopsy showed a specific type of inflammation known as granulomatous panniculitis, characterized by distinct granulomas and damage to fat cells and veins.
- The study highlights that while CD can cause different types of skin inflammation, EI/NV associated with CD often shows unique features, including granulomatous vasculitis and fat tissue involvement, setting it apart from other causes of EI/NV.
Erythema nodosum and erythema induratum (nodular vasculitis): diagnosis and management.
Dermatol Ther
November 2010
Department of Pathology, University of Virginia Health System, Charlottesville, Virginia, USA.
Article Synopsis
- - Erythema nodosum is the most common type of panniculitis, which can be triggered by various infections and immune responses, but its exact cause is still not completely understood.
- - Treatment focuses on addressing underlying causes and primarily involves nonsteroidal anti-inflammatory drugs, along with supportive care options like potassium iodide and colchicine.
- - Erythema induratum is a similar condition linked mostly to Mycobacterium tuberculosis and other disorders, and its treatment aligns with that of erythema nodosum after tackling the specific infection.
Erythema induratum of Bazin.
Dermatol Online J
April 2010
University of California Davis, Sacramento, California, USA.
Article Synopsis
- An 81-year-old woman with a history of kidney cancer presented with painful nodules on her lower extremities after having pulmonary nodules for years.
- A biopsy indicated she had nodular vasculitis, and further tests suggested erythema induratum of Bazin, likely linked to tuberculosis.
- Treatment with a standard antituberculous regimen led to significant improvement, highlighting how skin symptoms can indicate larger health issues.