188 results match your criteria: "Ernest E. Moore Shock Trauma Center[Affiliation]"

Are we ready for "green surgery" to promote environmental sustainability in the operating room? Results from the WSES STAR investigation.

World J Emerg Surg

January 2024

Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Via Alessandro Brambilla, 74, 27100, Pavia, PV, Italy.

Background: The importance of environmental sustainability is acknowledged in all sectors, including healthcare. To meet the United Nations Sustainable Development Goals 2030 Agenda, healthcare will need a paradigm shift toward more environmentally sustainable practices that will also impact clinical decision-making. The study investigates trauma and emergency surgeons' perception, acceptance, and employment of environmentally friendly habits.

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Hemorrhage remains the leading cause of preventable death on the battlefield and the civilian arena. Many of these deaths occur in the prehospital setting. Traumatic brain injury also represents a major source of early mortality and morbidity in military and civilian settings.

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Background: Despite advances and improvements in the management of surgical patients, emergency and trauma surgery is associated with high morbidity and mortality. This may be due in part to delays in definitive surgical management in the operating room (OR). There is a lack of studies focused on OR prioritization and resource allocation in emergency surgery.

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A role for decorin in improving motor deficits after traumatic brain injury.

Matrix Biol

January 2024

Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA. Electronic address:

Traumatic brain injury (TBI) is the leading cause of death and disability due to injury worldwide. Extracellular matrix (ECM) remodeling is known to significantly contribute to TBI pathophysiology. Glycosaminoglycans, which are long-chain, variably sulfated polysaccharides abundant within the ECM, have previously been shown to be substantially altered after TBI.

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Antibiotic prophylaxis in trauma: Global Alliance for Infection in Surgery, Surgical Infection Society Europe, World Surgical Infection Society, American Association for the Surgery of Trauma, and World Society of Emergency Surgery guidelines.

J Trauma Acute Care Surg

April 2024

From the General, Emergency and Trauma Surgery Department (F.C., C.C.), Pisa University Hospital, Pisa; General and Emergency Surgery (M.S.), Macerata Hospital, Macerata, Italy; Department of Surgery (R.S.), Western Michigan University Homer Stryker MD School of Medicine Kalamazoo, Michigan; Department of Surgery (K.R.), Anadolu Medical Center, Kocaali, Turkey; General, Emergency and Trauma Surgery Department (M.C.), Monza University Hospital, Monza; ICU Department (B.V.), Careggi Hospital, Firenze; Emergency and Trauma Surgery (F.C.), Maggiore Hospital, Parma, Italy; General and Emergency Surgery (D.D.), NHS Lothian, Edinburgh, United Kingdom; General, Emergency and Trauma Surgery Department (E.C.), Pavia University Hospital, Pavia, Italy; Ernest E Moore Shock Trauma Center at Denver Health (E.E.M.), Denver, Colorado; Trauma Surgery Department (W.L.B), Scripps Memorial Hospital, La Jolla, California; and Division of Trauma and Acute Care Surgery (R.C.) and Comparative Effectiveness and Clinical Outcomes Research Center (R.C.), Riverside University Health System, Moreno Valley, California.

Trauma is a complex disease, and the use of antibiotic prophylaxis (AP) in trauma patients is common practice. However, considering the increasing rates of antibiotic resistance, AP use should be questioned and limited only to specific cases. Antibiotic stewardship is of paramount importance in fighting resistance spread.

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Background: The use of Zone 1 REBOA for life-threatening trauma has increased dramatically.

Study Design: The Aortic Occlusion for Resuscitation in Trauma and Acute Care Surgery database was queried for blunt and penetrating trauma between 2013 and 2021. Outcomes were examined both for mechanisms of injury combined and separately and for combinations of abdominal injury with and without traumatic brain injury and chest injuries (Abbreviated Injury Scale [AIS] score >2).

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Background: Laparoscopy is widely adopted across nearly all surgical subspecialties in the elective setting. Initially finding indication in minor abdominal emergencies, it has gradually become the standard approach in the majority of elective general surgery procedures. Despite many technological advances and increasing acceptance, the laparoscopic approach remains underutilized in emergency general surgery and in abdominal trauma.

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Enhanced perioperative care protocols become the standard of care in elective surgery with a significant improvement in patients' outcome. The key element of the enhanced perioperative care protocol is the multimodal and interdisciplinary approach targeted to the patient, focused on a holistic approach to reduce surgical stress and improve perioperative recovery. Enhanced perioperative care in emergency general surgery is still a debated topic with little evidence available.

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Iatrogenic vascular air embolism is a relatively infrequent event but is associated with significant morbidity and mortality. These emboli can arise in many clinical settings such as neurosurgery, cardiac surgery, and liver transplantation, but more recently, endoscopy, hemodialysis, thoracentesis, tissue biopsy, angiography, and central and peripheral venous access and removal have overtaken surgery and trauma as significant causes of vascular air embolism. The true incidence may be greater since many of these air emboli are asymptomatic and frequently go undiagnosed or unreported.

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A core outcome set for appendicitis: A consensus approach utilizing modified Delphi methodology.

J Trauma Acute Care Surg

March 2024

From the Division of Trauma, Acute Care Surgery & Surgical Critical Care (C.A.B.), Department of Surgery, Reading Hospital-Tower Health, West Reading, Pennsylvania; Department of Surgery, University of Tennessee Health Science Center (S.B.), Memphis, Tennessee; UC Irvine Healthcare, Orange (J.N.), California; Department of Surgery, University of Alabama at Birmingham (R.G.), Birmingham, Alabama; University of Manitoba, Winnipeg (M.Z.), Manitoba, Canada; Department of Surgery, University of Texas Southwestern, Dallas (B.B.), Texas; Department of Surgery, University of Washington, Seattle (G.H.D.), Washington; AST5 ASR Marche, Hospital Madonna del Soccorso (S.D.S.), San Benedetto del Tronto, Italy; Department of Medicine, University of Illinois School of Medicine (T.J.E.), Peoria, Illinois; Department of Surgery, Columbia University Irving Medical Center (K.F.), New York, New York; Division of Trauma, Critical Care, Burns, and Emergency Surgery, Department of Surgery (B.J.), College of Medicine, University of Arizona, Tuscon, Arizona; Trauma, Emergency Surgery, and Surgical Critical Care (H.K.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Department of Gastroenterological Surgery (P.M., H.S.), Helsinki University Hospital, Helsinki, Finland; Department of General and Emergency Surgery (M.P.), Cagliari University Hospital, Cagliari, Italy; Division of Acute Care Surgery, Department of Surgery (J.V.S.), Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Surgery (P.S.), University of Turku, Turku, Finland; Department of Surgery, Western Michigan University School of Medicine: Western Michigan University Homer Stryker MD School of Medicine (R.G.S.), Kalamazoo, Michigan; Roy J. and Lucille A. Carver College of Medicine (D.S.), University of Iowa, Iowa City, Iowa; Division of General Surgery, Trauma and Surgical Critical Care, Acute Care Surgery (R.T.), Zuckerberg San Francisco General Hospital, San Francisco, California; and Ernest E Moore Shock Trauma Center at Denver Health (D.D.Y.), University of Colorado, Denver, Colorado.

Background: Appendicitis is one of the most common pathologies encountered by general and acute care surgeons. The current literature is inconsistent, as it is fraught with outcome heterogeneity, especially in the area of nonoperative management. We sought to develop a core outcome set (COS) for future appendicitis studies to facilitate outcome standardization and future data pooling.

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Article Synopsis
  • - Iatrogenic urinary tract injury (IUTI) is a serious complication that can arise from emergency digestive surgery, leading to increased health risks and long-term quality of life issues for patients.
  • - The incidence of IUTIs varies from 0.3% to 1.5%, highlighting the need for clear strategies for prevention and management, especially given the high number of these surgeries done globally.
  • - The World Society of Emergency Surgery (WSES) has developed guidelines based on extensive literature review and expert consultations, focusing on effective prevention measures, detection methods, and management strategies—including antibiotic use—pertaining to IUTIs in emergency settings.
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Objective: The aim of this study was to evaluate the association of annual trauma patient volume on outcomes for emergency medical services (EMS) agencies.

Background: Regionalization of trauma care saves lives. The underlying concept driving this is a volume-outcome relationship.

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Article Synopsis
  • This study investigates the effectiveness of measuring end tidal carbon dioxide (ETCO) in predicting mortality among trauma patients before they reach the hospital, using a nasal capnography cannula (NCC) or in-line ventilator circuit (ILVC).
  • Researchers collected ETCO data alongside other indicators like systolic blood pressure (SBP) and shock index (SI) from 550 trauma patients, finding that lower ETCO values were a better predictor of mortality compared to SBP and SI.
  • The results suggest that prehospital ETCO measurements can significantly aid in assessing the risk of mortality for injured patients, indicating their potential use in emergency medical settings.
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Article Synopsis
  • The study explores how traumatic brain injury (TBI) affects the body's thromboinflammatory response, emphasizing the need for personalized medicine in trauma care.
  • It utilizes 'omics' technology to analyze plasma from patients with TBI and non-TBI, revealing significant differences in proteins and metabolites, particularly in coagulation pathways and metabolic markers.
  • Findings suggest that TBI leads to increased levels of certain metabolites and highlights the potential for targeted research into treatments addressing neural inflammation and related complications.
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Laparotomy incisions provide easy and rapid access to the peritoneal cavity in case of emergency surgery. Incisional hernia (IH) is a late manifestation of the failure of abdominal wall closure and represents frequent complication of any abdominal incision: IHs can cause pain and discomfort to the patients but also clinical serious sequelae like bowel obstruction, incarceration, strangulation, and necessity of reoperation. Previous guidelines and indications in the literature consider elective settings and evidence about laparotomy closure in emergency settings is lacking.

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Objectives: Our understanding of blunt cerebrovascular injury (BCVI) has changed significantly in recent decades, resulting in a heterogeneous description of diagnosis, treatment, and outcomes in the literature which is not suitable for data pooling. Therefore, we endeavored to develop a core outcome set (COS) to help guide future BCVI research and overcome the challenge of heterogeneous outcomes reporting.

Methods: After a review of landmark BCVI publications, content experts were invited to participate in a modified Delphi study.

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Pediatric emergency resuscitative thoracotomy: A Western Trauma Association, Pediatric Trauma Society, and Eastern Association for the Surgery of Trauma collaborative critical decisions algorithm.

J Trauma Acute Care Surg

October 2023

From the Deparment of Surgery (M.J.M., K.I.), University of Southern California, Los Angeles, California; Deparment of Surgery (M.J.M.), Keck School of Medicine, Los Angeles, California; Deparment of Surgery (K.J.B.), Oregon Health Science University, Portland, Oregon; Deparment of Surgery (C.V.R.B.), Dell Medical School, University of Texas at Austin, Austin, Texas; Deparment of Surgery (J.L.H.), University of Kansas Medical Center, Kansas City, Kansas; Deparment of Surgery (M.d.M.), Medical College of Wisconsin, Milwaukee, Wisconsin; Deparment of Surgery (E.J.L.), Cedars-Sinai Medical Center, Los Angeles, California; Deparment of Surgery (E.E.M.), Ernest E Moore Shock Trauma Center, Denver, Colorado; Deparment of Surgery (K.A.P.), Scripps Mercy Hospital, San Diego, California; Deparment of Surgery (A.G.R.), Guthrie Health System, Sayre, Pennsylvania; Deparment of Surgery (N.G.R.), Children's Hospital, Cincinnati, Ohio; Deparment of Surgery (J.A.W.), St. Joseph's Medical Center, Phoenix, Arizona; Deparment of Surgery (R.C.), Riverside University Health System Medical Center, Riverside, California; Deparment of Surgery (M.C.), University of Florida College of Medicine, Jacksonville, Florida; Deparment of Surgery (K.M.), Loma Linda University Medical Center, Loma Linda; Deparment of Surgery (R.I.), University of California San Diego/Rady Children's Hospital, San Diego, California; Deparment of Surgery (S.L.), East Carolina University, Greenville, North Carolina; Deparment of Surgery (K.T.F.-O'B.), Medical College of Wisconsin, Children's Wisconsin, Milwaukee, Wisconsin; Deparment of Surgery (G.N.), Texas Tech University Health Sciences Center, El Paso, Texas; and Deparment of Surgery (L.S., M.J.), Oregon Health and Sciences University, Portland, Oregon.

Literature synthesis and expert opinion, Level V.

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[Acute mesenteric ischemia-An overview and recommendations (S2k analogous) of the World Society of Emergency Surgery].

Chirurgie (Heidelb)

July 2023

Klinik für Allgemein‑, Viszeral‑, Thorax‑, Transplantations- und Kinderchirurgie, Universitätsklinikum Gießen, Rudolf-Buchheim-Straße 7, 35392, Gießen, Deutschland.

Acute mesenteric ischemia is a severe illness, which if untreated, rapidly leads to a critical condition with sepsis, multiple organ failure and death in affected patients. The diagnosis and initiation of treatment of acute mesenteric ischemia should be performed as early and expeditiously as possible and follows the principle of the shortest possible time to reperfusion. Otherwise, the outcome of the patient rapidly deteriorates.

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Objective: Advanced mass spectrometry methods were leveraged to analyze both proteomics and metabolomics signatures in plasma upon controlled tissue injury (TI) and hemorrhagic shock (HS)-isolated or combined-in a swine model, followed by correlation to viscoelastic measurements of coagulopathy via thrombelastography.

Background: TI and HS cause distinct molecular changes in plasma in both animal models and trauma patients. However, the contribution to coagulopathy of trauma, the leading cause of preventable mortality in this patient population remains unclear.

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Early venous thromboembolism prophylaxis in patients with trauma intracranial hemorrhage: Analysis of the prospective multicenter Consortium of Leaders in Traumatic Thromboembolism study.

J Trauma Acute Care Surg

November 2023

From the Division of Trauma, Emergency Surgery, and Surgical Critical Care (Y.-T.W., C.-Y.C., K.M., M.S., K.I., M.J.M.), LAC+USC Medical Center, University of Southern California, Los Angeles, California; Department of Trauma and Emergency Surgery (Y.-T.W.), Chang Gung Memorial Hospital, Linkou; Department of General Surgery (C.-Y.C.), Chang Gung Memorial Hospital, Keelung, Taiwan; Department of Surgery (E.E.M.), Ernest E Moore Shock Trauma Center at Denver Health Center; School of Public Health (A.S.), University of Colorado, Denver, Colorado; and Department of Surgery (M.M.K.), University of California San Francisco, San Francisco, California.

Background: The optimal time to initiate venous thromboembolism prophylaxis (VTEp) for patients with intracranial hemorrhage (ICH) is controversial and must balance the risks of VTE with potential progression of ICH. We sought to evaluate the efficacy and safety of early VTEp initiation after traumatic ICH.

Methods: This is a secondary analysis of the prospective multicenter Consortium of Leaders in the Study of Thromboembolism study.

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Article Synopsis
  • The study investigates the effectiveness of tissue plasminogen activator (tPA) combined with thrombelastography (TEG) to predict massive transfusion (MT) in trauma patients with hypotension.
  • It analyzes trauma activation patients with early or delayed hypotension, comparing tPA-challenge-TEG's predictive performance to existing strategies using receiver operating characteristics curves.
  • Results show that tPA-challenge-TEG is the best predictor of MT for early hypotension cases and performs well in delayed hypotension cases, offering insights for early MT recognition.
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Titratable partial aortic occlusion: Extending Zone I endovascular occlusion times.

J Trauma Acute Care Surg

August 2023

From the Division of General Surgery (D.G., J.R., A.B.), St. Michael's Hospital, and Li Ka Shing Knowledge Institute (D.G., A.N., J.R., A.B.), Unity Health Toronto; Department of Surgery (D.G., J.R., A.B.), Temetry Faculty of Medicine, and Institute of Health Policy, Management and Evaluation (D.G.), University of Toronto, Toronto, Ontario, Canada; Division of Acute Care Surgery (B.M.D.), Vanderbilt University Medical Center, Nashville, Tennessee; Program in Trauma (R.K.), R Adams Cowley Shock Trauma Center, University of Maryland, Baltimore, Maryland; Division of Acute Care Surgery (E.B.), Grady Memorial Hospital, Atlanta, Georgia; Ernest E Moore Shock Trauma Center at Denver Health (R.L., E.E.M.), University of Colorado Denver, Denver, Colorado; Department of Surgery (J.N.), Morehouse School of Medicine, Atlanta, Georgia; Norman McSwain Trauma Center (J.D.), Tulane Acute Care Surgery, New Orleans, Louisiana; Division of Trauma and Acute Care Surgery (C.S., S.D.), Grant Medical Center, Columbus, Ohio; and Prytime Medical Devices (C.V.S.), San Antonio, Texas.

Background: Extending the time to definitive hemorrhage control in noncompressible torso hemorrhage (NCTH) is of particular importance in the battlefield where transfer times are prolonged and NCTH remains the leading cause of death. While resuscitative endovascular balloon occlusion of the aorta is widely practiced as an initial adjunct for the management of NCTH, concerns for ischemic complications after 30 minutes of compete aortic occlusion deters many from zone 1 deployment. We hypothesize that extended zone 1 occlusion times will be enabled by novel purpose-built devices that allow for titratable partial aortic occlusion.

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Feasibility of conducting a military-relevant multicenter cohort study to assess outcomes of early trauma resuscitative interventions in a prolonged care civilian setting.

J Trauma Acute Care Surg

August 2023

From the Department of Emergency Medicine (N.-K.M.-M., J.M.D., C.F.), School of Medicine, University of Colorado Denver, Aurora, Colorado; Division of Surgery (H.J.L.), Stellenbosch University, Cape Town, South Africa; Adult and Child Consortium for Health Outcomes Research and Delivery Science (B.B.), and Department of Biostatistics and Informatics (B.F.), Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado; Emergency Medical Services (S.d.V.), Western Cape Government, Cape Town, South Africa; US Army Institute for Surgical Research (S.G.S.), Joint Base San Antonio, Fort Sam Houston, Texas; Division of Surgery (E.S.), and Division of Forensic Medicine (J.V.), Stellenbosch University; Worcester Hospital (L.H.), Khayelitsha Hospital (S.M.), and Ceres Hospital (K.D.), Western Cape Government Department of Health; Division of Emergency Medicine (W.S.), University of Cape Town, Cape Town, South Africa; Department of Emergency Medicine (S.K.), School of Medicine, University of Colorado Denver, Aurora, Colorado; US Department of Defense Joint Trauma System En Route Combat Casualty Care (C.C.), San Antonio, Texas; Department of Surgery (E.E.M.), Ernest E. Moore Shock Trauma Center at Denver Health, Denver; Department of Emergency Medicine (A.A.G.), and Department of Emergency Medicine (V.S.B.), School of Medicine, University of Colorado Denver, Aurora, Colorado.

Background: The Epidemiology and Outcomes of Prolonged Trauma Care (EpiC) study is a 4-year, prospective, observational, large-scale epidemiologic study in South Africa. It will provide novel evidence on how early resuscitation impacts postinjury mortality and morbidity in patients experiencing prolonged care. A pilot study was performed to inform the main EpiC study.

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