5,392 results match your criteria: "Epworth Hospital; and.[Affiliation]"

Purpose: Pharyngeal residue rating scales are often used to rate pharyngeal residue observed during flexible endoscopic evaluation of swallowing. Despite the widespread use of pharyngeal residue rating scales, there is no data that has systematically explored user experience. The aim of this scoping review was to investigate specific reporting of user experience, user centred design principles, and normative data in the development of pharyngeal residue rating scales.

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Background: OSA causes episodes of fragmented sleep and intermittent hypoxia and leads to excessive daytime sleepiness (EDS). Deficits in cognitive function are a troublesome symptom in patients with OSA and EDS.

Research Question: How does solriamfetol affect cognitive function in patients with cognitive impairment associated with OSA and EDS?.

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Initial Assessment of Resectability of Colorectal Cancer Liver Metastases Versus Clinical Outcome.

Clin Colorectal Cancer

October 2024

Personalised Oncology Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia; Department of Medical Oncology, Western Health, Footscray, Victoria, Australia.

Background: Surgery improves long-term survival for resectable, liver-only metastatic colorectal cancer (mCRC). With no consensus definition of "resectable" disease, decisions regarding resectability are reliant on the expertise and judgement of the treating clinician working in consultation with a multidisciplinary team (MDT). This study examines the clinical outcome versus initial assessment of resectability in an Australian population with mCRC.

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Background: For children and adolescents with cerebral palsy (CP) who are independently ambulant (Gross Motor Function Classification System (GMFCS) I or II), running is a fundamental movement skill that enables them to play and engage in school and community activities. A running intervention which resulted in good running goal attainment should logically have improved running kinematics, however, this has not yet been established.

Research Question: Does a low-load plyometric running intervention improve joint kinematics during running in children with CP?

Methods: Three-dimensional gait analysis was undertaken before and after a 12-week intervention.

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: Biochemical recurrence (BCR) after radical prostatectomy (RP) is a significant predictor of distal metastases and mortality in prostate cancer (PCa) patients. This systematic review aims to evaluate the accuracy of artificial intelligence (AI) in predicting BCR post-RP. : Adhering to PRISMA guidelines, a comprehensive literature search was conducted across Medline, Embase, Web of Science, and IEEE Xplore.

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Impaired balance is a key symptom following acute concussion. Unfortunately, the recommended clinical balance assessment lacks sensitivity and discriminative ability, relying on the experience of the clinician for interpretation. The aim of this pilot study is to explore smartphone technology to remotely assess balance impairment in people with acute concussion.

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Effects of sleeve gastrectomy on populations with obesity and obstructive sleep apnea: a meta-analysis.

Surg Obes Relat Dis

October 2024

Department of General Surgery, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China. Electronic address:

Background: Obstructive sleep apnea (OSA) is highly prevalent in patients with morbid obesity, prompting interest in bariatric surgery as a potential management strategy. Sleeve gastrectomy (SG), being the primary bariatric surgical option, offers simplicity, reduced postoperative complications, and favorable outcomes for obesity and its associated conditions.

Objectives: This study aims to assess the efficacy of SG in treating populations with obesity and OSA.

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Sleep quality, daytime sleepiness, and risk of falling: results from an exploratory cross-sectional study.

Eur Geriatr Med

November 2024

Sleep Disorder Centre, Department of Medical Sciences, and Public Health, University of Cagliari, SS 554 Bivio Sestu, 09042 Monserrato, Cagliari, Italy.

Article Synopsis
  • The study investigates the link between sleep quality and daytime sleepiness with fall risk in older adults aged 75 and above.
  • Conducted in Italy, the research assessed 206 participants using sleep quality metrics and fall risk evaluations, revealing that a significant number had poor sleep quality and excessive daytime sleepiness.
  • Findings indicate that poor sleep quality and excessive daytime sleepiness significantly increase the risk of falls, suggesting these factors should be managed in elderly care.
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Background: There is a lack of comprehensive data sources on various rating instruments that have been developed, translated, and adapted in Indian context.

Aim: Accordinly, this review aimed to compile the available scales/questionnaires/instruments developed, adapted, and translated for use in India.

Methods: For this, the search engines like PUBMED, Google Scholar, MedKnow, and Science Direct were searched for scales that have been developed, translated, and adapted in Indian context or an Indian language.

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Introduction: Nicotine addiction is one of the most common forms of dependence. It is shown to be associated with many chronic diseases that develop mostly through smoking. The association between sleep quality and smoking or nicotine addiction has not been clarified yet.

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Article Synopsis
  • - Restless legs syndrome (RLS) disrupts sleep and lowers quality of life, leading researchers to develop the RLS-Self-care Behaviour questionnaire (RLS-ScBq) to measure self-care activities for patients with this condition.
  • - The study with 788 patients assessed the questionnaire's validity and reliability, finding it useful for evaluating physical and mental self-care actions in managing RLS.
  • - Results indicated a two-factor solution with decent internal consistency, suggesting the RLS-ScBq could help healthcare professionals understand and promote self-care in RLS patients.
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Introduction: Generalized anxiety disorder (GAD) is a common mental disorder that often begins in adolescence or early adulthood and is characterized by widespread and persistent anxiety. Partial sleep deprivation (PSD) is an important risk factor for GAD development and a common comorbidity. Adolescence is a period of rapid brain and nervous system development, and during this time, the occurrence of GAD can lead to neurocognitive deficits, such as impaired attention, cognitive control, and attention bias, that significantly affect cognitive function.

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Development and Validation of a Nomogram for Predicting Non-Adherence to Continuous Positive Airway Pressure Therapy in Patients with Obstructive Sleep Apnea.

Nat Sci Sleep

October 2024

Department of Otolaryngology Head and Neck Surgery, Changde Hospital, Xiangya School of Medicine, Central South University, Changde, People's Republic of China.

Background: Continuous positive airway pressure (CPAP) is an effective treatment for obstructive sleep apnea (OSA), but its long-term efficacy is limited by poor patient adherence. This study aimed to develop and validate a predictive nomogram for CPAP non-adherence in patients with OSA.

Methods: This is a secondary analysis of a retrospective study.

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Association of sleep disturbances with diminished ovarian reserve in women undergoing infertility treatment.

Sci Rep

November 2024

Department of respiratory and critical care medicine, Institute of Respiratory Disease, First Affiliated Hospital of Fujian Medical University, Fujian Medical University, Fujian Provincial Sleep-disordered Breathing Clinic Center, Fuzhou, China.

With an aging population seeking infertility treatment, diminished ovarian reserve (DOR) is a prevalent indication for assisted reproductive technology (ART). This study aims to investigate the relationship between sleep parameters and DOR among women attending an infertility clinic. Methods We consecutively enrolled women attending an infertility clinic from July 2020 to June 2021.

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Background: Tonsillectomy is an effective treatment option for obstructive sleep apnoea in selected adult patients, but there has been a lack of long-term follow-up data.

Objectives: To analyse the long-term outcomes of extracapsular tonsillectomy in the treatment of obstructive sleep apnoea in adults, with the longest follow-up periods to date.

Materials And Methods: We recruited adults who had undergone extracapsular tonsillectomy because of obstructive sleep apnoea between 2004 and 2018 in the Hospital District of Southwest Finland.

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Article Synopsis
  • A scoping review examined barriers and enablers to effective weight management for individuals with obesity in high-income countries, analyzing 216 relevant studies.
  • Three main themes identified were healthcare provider-related factors, the provision of care, and policy/funding issues.
  • Key barriers included lack of provider knowledge and prioritization of obesity management, while enablers highlighted the need for improved education, consistent policies, and increased funding for comprehensive care.
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Article Synopsis
  • The study evaluates a modified "Baveno classification" for treating obstructive sleep apnoea (OSA) by incorporating a cardiovascular disease (CVD) risk score and considering severe breathing issues.
  • Researchers analyzed data from 8,625 OSA patients, categorizing them into risk groups and assessing the impact of treatment over 12-24 months using results from the Epworth Sleepiness Scale (ESS) and systolic blood pressure (SBP).
  • Findings show that treatment indications increased with higher CVD risk, and significant improvements in sleepiness and blood pressure were noted, supporting the importance of CVD assessment in OSA management.
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Introduction: Preclinical and clinical evidence has elucidated that cannabis-based medical formulations (CBMFs) may display anxiolytic, antidepressive, and neuroprotective properties. CBMFs are often considered as novel therapeutic anxiolytic agents that can be prescribed as pharmacotherapy for symptomatic domains in anxiety disorders (ADs). Our aim was to explore effectiveness and tolerability of enriched cannabidiol (CBD) oil extract formulations in adults with anxiety symptoms in an outpatient mental health program in Colombia during the COVID-19 pandemic.

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Introduction: Allergic rhinitis (AR) is a chronic condition caused by an immunoglobulin E-mediated response to environmental allergens, which affects 10-40% of the global population. AR symptoms, such as nasal congestion and rhinorrhea, significantly reduce quality of life and are associated with sleep disturbances, further exacerbating the condition's burden. Despite the known impact of AR on sleep, the effects of intranasal corticosteroids on sleep quality have not been comprehensively reviewed.

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We aimed to evaluate the presence of sleep-disordered breathing (SDB) in generalized anxiety disorder (GAD) patients and its impacts after 12-week of escitalopram treatment. In this prospective observational study, GAD patients were followed up to determine whether comorbid SDB affects their treatment response. They underwent a home sleep apnea test (HSAT), and oxygen desaturation index ≥5 was considered indicative of SDB.

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This study evaluated patient-reported outcomes (PROs) of Medicine Access Programmes (MAPs) for Australian metastatic breast cancer patients on ribociclib. Limited patient awareness of MAP enrolment was identified, emphasising the need for improved education and consent processes. Most patients expressed gratitude for accessing non-funded medications and perceived enhanced medication adherence as a key benefit.

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Depressive Symptoms and Gut Microbiota after Bowel Preparation and Colonoscopy: A Pre-Post Intervention Study.

Microorganisms

September 2024

The Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine and Barwon Health, Deakin University, Geelong, VIC 3220, Australia.

Mechanical bowel preparation (MBP) is essential for visualisation of the colon during colonoscopy. Previous studies have identified changes in gut microbiota composition after MBP and colonoscopy. Considering the gut microbiota is increasingly implicated in psychiatry, we explored the potential impact of this intervention on mood and the microbiota-gut-brain axis.

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Objective: To assess fertility treatment outcomes according to primary language spoken in patients undergoing fertility treatment in an Australian setting.

Methods: This retrospective cohort study examined female patients who received fertility treatment through a public hospital fertility service between September 2020 and May 2023. The primary outcome was clinical pregnancy rate following embryo transfer for patients who spoke English and patients who primarily spoke a language other than English.

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