Which performance indicators are used globally for evaluating healthcare in patients with a hip fracture? : a mixed methods systematic review.

Aims: Performance indicators are increasingly used to evaluate the quality of healthcare provided to patients with a hip fracture. The aim of this review was to map the variety of performance indicators used around the world and how they are defined.

Methods: We present a mixed methods systematic review of literature on the use of performance indicators in hip fracture care.

Reactive Hypoglycaemia at Glucose Tolerance Test-Another Presentation of Gestational Diabetes: A Multicentre Retrospective Study.

Objective: To assess obstetric outcomes in pregnant women with 'reactive hypoglycaemia' (RH) during an oral glucose tolerance test (OGTT), defined as a 2-h blood glucose level lower than the fasting value.

Design: Retrospective observational study.

Setting: Two tertiary maternity units in the United Kingdom.

The Evolving Paradigm of Myocardial Infarction in the Era of Artificial Intelligence.

The classification and treatment of myocardial infarction (MI) have evolved significantly over the past few decades, with the ST-segment elevation myocardial infarction (STEMI)/non-STEMI (NSTEMI) paradigm dominating clinical practice. While STEMI, identified by ST-segment elevation (STE) on electrocardiogram (ECG), has been the hallmark for urgent reperfusion therapy, this model misses a substantial number of patients with occlusive myocardial infarction (OMI) who do not exhibit STE. Recent evidence reveals that up to 25% of NSTEMI patients have OMI, leading to higher mortality due to delayed reperfusion.

Fasting appetite-related gut hormone responses after weight loss induced by calorie restriction, exercise, or both in people with overweight or obesity: a meta-analysis.

Objectives: Altered appetite-related gut hormone concentrations may reflect a physiological adaptation facilitating weight regain after weight loss. This review investigates hormonal changes after weight loss achieved through calorie restriction (CR), exercise (EX), or both combined (CREX).

Methods: A systematic search of PubMed (MEDLINE), EMBASE, SPORTDiscus, Cochrane Library, Web of Science, and ClinicalTrials.

Nutrition Status of People Experiencing Homelessness Residing in Temporary Accommodation in London.

Objectives: London has the highest proportion of people experiencing homelessness (PEH) living in temporary accommodation in the United Kingdom. PEH have poorer health outcomes, greater dietary inequalities, and die younger than the general population. Despite this, little is known about the nutrition status of PEH.

Preoperative peripheral nerve blocks are not independently associated with improved functional outcome, patient satisfaction, or risk of chronic pain at one year following knee arthroplasty.

Aims: Control of acute pain following knee arthroplasty (KA) with a perioperative peripheral nerve block (PNB) may improve functional outcomes and reduce the risk of chronic postoperative knee pain (CPKP). The aims of this study were to assess whether a PNB influences patient-reported outcomes and risk of CPKP at one year following KA.

Methods: A retrospective study was conducted over a two-year period and included 3,338 patients who underwent KA, of whom 1,434 (43.

Assessment of frailty in patients with heart failure: A new Heart Failure Frailty Score developed by Delphi consensus.

Aims: The Heart Failure Frailty Score (HFFS) is a novel, multidimensional tool to assess frailty in patients with heart failure (HF). It has been developed to overcome limitations of existing frailty assessment tools while being practical for clinical use. The HFFS reflects the concept of frailty as a multidimensional, dynamic and potentially reversible state, which increases vulnerability to stressors and risk of poor outcomes in patients with HF.

The cytotoxic/genotoxic role of impurities in soluble minerals: The case of natural (fibrous epsomite) versus synthetic (Epsom salt) magnesium sulphate.

Epsomite and Epsom salt are very common mineral phases, and many known uses are found in agriculture, and in food and pharmaceutical industries. Natural epsomite can be fibrous and inhalable, potentially reaching the digestive tract after dissolving in mucus and saliva. Epsom salt is a common food additive (E 518) to which humans can be exposed daily, although its health effects are still debated.

Comparison of glycosylated fibronectin versus soluble fms-like tyrosine kinase/placental growth factor ratio testing for the assessment of pre-eclampsia: protocol for a multicentre diagnostic test accuracy study.

Introduction: Pre-eclampsia is a condition associated with significant maternal and neonatal morbidity and mortality. The prediction of pre-eclampsia in high-risk populations using angiogenic markers, such as serum placental growth factor (PlGF) assessment, has been shown to improve maternal outcomes and is recommended by the National Institute for Health and Care Excellence (NICE). However, such tests are not yet available at the point of care (POC).

Prevalence of complications in older adults after hip fracture surgery : a systematic review and meta-analysis.

Aims: Older adults with hip fractures are at high risk of experiencing complications after surgery, but estimates of the rate of specific complications vary by study design and follow-up period. The aim of this systematic review was to determine the prevalence of complications in older adults after hip fracture surgery.

Methods: MEDLINE, Embase, CINAHL, and CENTRAL databases were searched from inception until 30 June 2023.

Understanding and Deterring Online Child Grooming: A Qualitative Study.

The prevalence of online child sexual grooming offenses has been on the rise, posing significant risks to children. Child sexual grooming involves sexual communication with minors. This study aims to understand motivations and pathways of individuals who have engaged in online grooming behaviour, as well as propose effective prevention and intervention strategies.

Revolutionising Osseous Biopsy: The Impact of Artificial Intelligence in the Era of Personalised Medicine.

In a rapidly evolving healthcare environment, artificial intelligence (AI) is transforming diagnostic techniques and personalised medicine. This is also seen in osseous biopsies. AI applications in radiomics, histopathology, predictive modelling, biopsy navigation, and interdisciplinary communication are reshaping how bone biopsies are conducted and interpreted.

Diffusion weighted imaging to predict longer term response in Crohn's disease patients commencing biological therapy: Results from the MOTILITY Trial.

Objectives: Predicting longer term response to biological therapy for small bowel Crohn's disease (SBCD) is an unmet clinical need. Diffusion-weighted MR imaging (DWI) may indicate disease activity, but its predictive ability, if any, is unknown. We investigated the prognostic value of DWI for one year response or remission (RoR) in SBCD patients commencing biologic therapy, including incremental value over C-reactive protein (CRP) and faecal calprotectin (FC).

Lupus psychosis: an unusual cause of acute confusion presenting to acute medicine.

A young lady was brought to the hospital by the police after they found her wandering in the streets far away from her home behaving oddly. At admission, she was confused and had various delusional thoughts accompanied by visual and auditory hallucinations. After she was identified and her old medical notes were retrieved, it was found that she had a diagnosis of systemic lupus erythematosus (SLE) previously for which she declined any treatment.

Qualitative methods: the missing link in orthopaedic research.

Cite this article:  2025;14(1):16–19.

Iron management and exercise training in individuals with chronic kidney disease: lived experiences.

Background: Non-anaemic iron deficiency is highly prevalent in people living with chronic kidney disease (CKD) but is underdiagnosed and undertreated, especially in earlier stages of CKD. A multicentre trial assessing the effect of intravenous iron supplementation in iron-deficiency but not anaemic people with CKD included a qualitative sub-study that aimed to explore the patient experience and psychosocial impact of living with CKD and iron deficiency, and the experience of the therapeutic intervention (intravenous iron and exercise).

Methods: Semi-structured interviews were conducted with 23 trial participants blinded to treatment.

Blended soil amendments: A viable strategy to reduce soluble phosphorus in soils.

Phosphorus (P) loss from soils can contribute significantly toward P enrichment in water bodies, impairing water quality. Application of soil amendments is a viable strategy to decrease soluble P in surface soils. Since soluble P is reduced through different mechanisms that are amendment-specific, blended amendments could be a better approach than single amendment applications; however, very little information is available on blended amendment effects in reducing P loss from soils.

Head and Neck Squamous Cell Carcinoma of Unknown Primary-Who Can Be Offered Surgery as the Sole Treatment Modality? A Systematic Review.

Objective: Evaluate the role of surgery as the sole treatment modality for patients with cervical head and neck squamous cell carcinoma of unknown primary (HNSCCUP).

Design: Systematic review of observational cohort studies with qualitative synthesis.

Setting: PubMed, Ovid EMBASE, and Cochrane Controlled register of Trials (CENTRAL) were screened from January 2000 up to October 2021.

The Oxford hip score demonstrates moderate ceiling effects at one and two years after total hip arthroplasty: which patients are at risk and does it matter?

Background: The aim was to assess whether the postoperative Oxford Hip Score (OHS) demonstrated a ceiling effect at 1 or 2 years after total hip arthroplasty (THA) and to identify which patients are more likely to achieve a ceiling score and whether this limits assessment of their outcome.

Methods: A retrospective cohort of 7871 patients undergoing primary THA was identified from an established arthroplasty database. Patient demographics, ASA grade, socioeconomic status, OHS and EuroQol questionnaire were collected preoperatively and at 1 and 2 years postoperatively.

The British Geriatrics Society's position on assisted dying.

In response to increased focus on the issue of Assisted Dying (AD) in the UK due to the presentation of The Terminally Ill Adults (End of Life) Bill 2024-25 [1] and bills before parliaments in the Isle of Man, Guernsey and Scotland, the British Geriatric Society (BGS) recently developed a position statement opposing legalisation of AD in the UK [2]. We set out our key reasoning behind this position, namely the current adverse health and social care context and significant concern about whether effective safeguards can be created to protect older people with complex needs from undue harms. The BGS asks for improved, personalised, multidisciplinary care for older people at the end of their lives, including high-quality palliative and end-of-life care.

A multi-centre UK-based survey on angioedema secondary to acquired C1 inhibitor deficiency.

Background: Acquired angioedema due to C1-inhibitor deficiency (AAE-C1-INH) is very rare compared to its prototype, hereditary angioedema. An updated characterisation of the AAE-C1-INH cohort in UK is required to inform management.

Objectives: To describe the disease burden of AAE-C1-INH, long-term prophylaxis (LTP) and the clinical, immunochemical and treatment profiles of AAE-associated diseases in UK.

The ADHD Assessment Quality Assurance Standard for Children and Teenagers (CAAQAS).

Around 5% of the children and teenagers worldwide are affected by Attention-Deficit/Hyperactivity Disorder [ADHD], making it a major public health concern. Recently, demand for assessments has substantially increased, putting strain on healthcare and waiting lists. There is concern that pressure to clear service bottlenecks is leading to variable quality and reliability of ADHD assessments in this population.