The study evaluated long-term adrenocorticotropic therapy (LT-ACTH) for preventing relapses in West syndrome (WS) and assessed adverse effects through a retrospective analysis of 16 children with the condition.
The results showed a nonrelapse rate of 60.6% at 24 months post-treatment, with some patients experiencing relapses during the weekly injection phase.
While LT-ACTH could be a promising treatment option for intractable WS, the study's limitations include a small sample size and lack of long-term safety data.