588 results match your criteria: "Epidural and Subdural Infections"

Case: A 73-year-old woman, after spinal surgery, presented with symptomatic spinal subdural extra-arachnoid hygroma (SSEH) because of a fall on the third postoperative day. The hygroma was diagnosed by magnetic resonance imaging (MRI). Lumbar puncture was performed under local anesthesia, after which the leg pain disappeared immediately.

View Article and Find Full Text PDF

Optimal treatment and outcome after spinal hematoma remain unclear. Close neurological monitoring is the key to successful treatment. Here, we present a case of an infected spinal hematoma management.

View Article and Find Full Text PDF
Article Synopsis
  • - Atypical spinal infections (ASIs) pose significant challenges in management due to their subtle onset and serious complications, making early recognition crucial.
  • - Diagnosis involves monitoring inflammatory markers and culturing organisms, followed by treatment with antibiotics and possible surgical procedures like decompression or fusion based on spine stability.
  • - Timely intervention can reduce neurological impairments and the length of treatment, and advancements in surgical techniques have improved outcomes for patients with ASIs.
View Article and Find Full Text PDF

There are no clinical guidelines for performing nephrectomy in patients with autosomal recessive polycystic kidney disease (ARPKD). Few reports have described the clinical course of ARPKD diagnosed in the neonatal period in detail. Here, we report seven patients diagnosed with ARPKD and treated at our center during the neonatal period.

View Article and Find Full Text PDF

A 20-Year Study of Intracranial Pyogenic Complications of Sinusitis in Children.

Pediatr Infect Dis J

February 2024

From the Division of Infectious Diseases, The Hospital for Sick Children, Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada.

Article Synopsis
  • Intracranial pyogenic complications from sinusitis in children can lead to serious health issues, as revealed by a 20-year study examining clinical and microbiologic data from 104 cases.
  • The majority of affected children were male, with common complications including epidural and subdural empyema, and a significant portion required neurosurgery or otolaryngologic intervention.
  • The findings highlight the prevalence of Streptococcus anginosus and polymicrobial infections, indicating the necessity for broad-spectrum antibiotics and the importance of timely diagnosis to reduce the likelihood of lasting neurologic effects.
View Article and Find Full Text PDF

Imaging in spinal infections: Current status and future directions.

N Am Spine Soc J

December 2023

Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, Connecticut.

Article Synopsis
  • Imaging is crucial for diagnosing spinal infections, as early detection significantly improves treatment outcomes.
  • The article covers various spinal infections including pyogenic and tuberculous spondylodiscitis, septic facet arthritis, and abscesses, highlighting their imaging techniques.
  • While MRI is the preferred method due to its sensitivity, CT and nuclear medicine imaging are important alternatives in certain situations and are also useful for guiding biopsies.
View Article and Find Full Text PDF

Background: Spinal infections are associated with a wide variety of clinical conditions, including osteomyelitis, spondylitis, diskitis, septic facet joints, and abscesses. Based on its anatomical relationship with the dura mater, the abscess can be epidural (extradural) or subdural (intrathecal). Subdural intramedullary abscesses of the lumbar spinal canal are more common than subdural extramedullary abscesses.

View Article and Find Full Text PDF

Objective: Septic cerebral venous sinus thrombosis (CVST) is a recognized complication of pediatric sinogenic and otogenic intracranial infections. The optimal treatment paradigm remains controversial. Proponents of anticoagulation highlight its role in preventing thrombus propagation and promoting recanalization, while others cite the risk of hemorrhagic complications, especially after a neurosurgical procedure for an epidural abscess or subdural empyema.

View Article and Find Full Text PDF

Actinomycosis is a chronic, indolent, granulomatous disease process caused by the genus of bacteria. More severe forms of actinomycosis include disseminated or central nervous system (CNS) infections. is the most common species of isolated from brain abscesses.

View Article and Find Full Text PDF

Staged or simultaneous operations for ventriculoperitoneal shunt and cranioplasty: Evidence from a meta-analysis.

CNS Neurosci Ther

November 2023

Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

Objective: To date, there is no consensus on the surgery strategies of cranioplasty (CP) and ventriculoperitoneal shunt (VPS) placement. This meta-analysis aimed to investigate the safety of staged and simultaneous operation in patients with comorbid cranial defects with hydrocephalus to inform future surgery protocols.

Methods: A meta-analysis of PubMed, Ovid, Web of Science, and Cochrane Library databases from the inception dates to February 8, 2023 adherent to PRISMA guidelines was conducted.

View Article and Find Full Text PDF
Article Synopsis
  • A systematic literature review was conducted on the use of sonolucent cranioplasty (SC) with transcranioplasty ultrasonography, analyzing data from 16 eligible studies involving 189 patients, primarily females aged from teens to 80s.
  • Key indications for the SC procedures included hydrocephalus, tumor, traumatic brain injury, and intracerebral hemorrhage.
  • The review identified various complications associated with SC, such as wound infections and cerebrospinal fluid leaks, and recommended future studies focus on collecting quantitative measurement data to improve the validation of imaging techniques.
View Article and Find Full Text PDF
Article Synopsis
  • Intracranial infections often stem from sinus infections, primarily caused by Streptococcus intermedius, leading to a need for effective microbiological assessment through sampling.* ! -
  • A study conducted on 31 patients over three years revealed that only 7% had matching pathogens in both intracranial and sinus samples, indicating a discrepancy in diagnosis and the need for better sampling methods.* ! -
  • The research highlighted that 50% of sinus samples failed to identify the main brain pathogen, emphasizing the importance of intracranial sampling for accurate diagnosis and treatment.* !
View Article and Find Full Text PDF

The purpose of this study is to investigate the risk factors of intracranial complications in adult patients with Pott Puffy Tumor (PPT). A systematic review was conducted of clinical studies from January 1983 to December 2022 that reported on PPT adult patients. The full-text articles were reviewed for the patients' ages, sex, cultured organisms, surgical procedures, clinical sequalae, and underlying diseases that may affect the onset of intracranial complications in PPT adult patients.

View Article and Find Full Text PDF

Background: Fitusiran, a subcutaneous investigational siRNA therapeutic, targets antithrombin with the goal of rebalancing haemostasis in people with haemophilia A or haemophilia B, regardless of inhibitor status. We aimed to evaluate the efficacy and safety of fitusiran prophylaxis in people with severe haemophilia without inhibitors.

Methods: This multicentre, open-label, randomised phase 3 study was conducted at 45 sites in 17 countries.

View Article and Find Full Text PDF
Article Synopsis
  • Sinusitis is a frequent infection in kids that can sometimes lead to serious brain complications if not treated quickly.
  • The case discusses a 13-year-old boy who had suspected sinusitis and developed a thrombosis in a brain vein, plus collections of pus in the brain's protective layers.
  • If these types of complications occur, they can lead to significant health issues or even death, highlighting the importance of timely medical intervention.
View Article and Find Full Text PDF

Background: The coronavirus disease 2019 (COVID-19) pandemic affected all countries' health systems and people's lifestyles. In this study, we aimed to investigate its effects in a university hospital neurosurgery clinic.

Methods: The 2019 year's 6 months' data as a prepandemic period compared to the 2020 year's same period as a pandemic date.

View Article and Find Full Text PDF

Objectives: Motor cortex stimulation (MCS) is an effective technique in treating chronic intractable pain for some patients. However, most studies are small case series (n < 20). Heterogeneity in technique and patient selection makes it difficult to draw consistent conclusions.

View Article and Find Full Text PDF

Objective: This study aimed to evaluate the management practices and outcomes in children with sinogenic intracranial suppuration.

Method: This was a retrospective cohort study in a single paediatric tertiary unit that included patients younger than 18 years with radiologically confirmed intracranial abscess, including subdural empyema and epidural or intraparenchymal abscess secondary to sinusitis. Main outcomes studied were rate of return to the operating theatre, length of hospital stay, death in less than 90 days and neurological disability at 6 months.

View Article and Find Full Text PDF

Pott's puffy tumor (PPT) is a life-threatening complication of infectious sinusitis/osteomyelitis of the frontal bone. It occurs due to infection or trauma and is often seen in late childhood and adolescence. If left untreated for a protracted period, intracranial complications such as epidural abscess, subdural empyema, meningitis, and a cerebral abscess may occur.

View Article and Find Full Text PDF
Article Synopsis
  • - Recent research indicates that spinal infections are becoming more common, but cases involving multiple compartments in the spine are uncommon.
  • - This report documents a unique case of a tetra-compartmental spinal infection that involved the epidural, subdural, subarachnoid, and intramedullary areas, linked to a severe condition requiring surgery.
  • - The findings emphasize the critical role of surgery for severe infections, the necessity of MRI for monitoring the infection's spread, and the importance of using intraoperative ultrasound to assess complex spinal infections.
View Article and Find Full Text PDF

Background: Patients with head trauma may develop hydrocephalus after decompressive craniectomy. Many studies have referred one-stage cranioplasty (CP) and ventriculoperitoneal shunt (VPS) was applied to treat cranial defect with post-traumatic hydrocephalus (PTH), but the safety and efficiency of the procedure remain controversial.

Methods: This is a retrospective cohort study including 70 patients of PTH following decompressive craniectomy who underwent simultaneous (50) and separated (20) procedures of cranioplasty and VPS from March 2014 to March 2021 at the authors' institution with at least 30 days of follow-up.

View Article and Find Full Text PDF

Background: Extra axial abscess of the brain is a rare entity, moreover, extra-axial abscess concomitant with intraparenchymal purulent collections are scarcely reported in the literature. Etiology includes penetrating trauma, paranasal sinusitis, mastoiditis, craniospinal surgeries, and the rare spread of infectious agents through the hematogenous route.

Case Description: We present a case of a young male with Burkholderia pseudomallei Central Nervous System (CNS) melioidosis, forming abscesses in extra-axial and intraparenchymal planes without contiguity.

View Article and Find Full Text PDF

Chronic subdural hematomas (CSDHs) are a common neurosurgical disease for which middle meningeal artery (MMA) embolization is emerging as an attractive and efficacious endovascular treatment modality. We present the first known case of a epidural abscess that resulted following MMA embolization for a left-sided CSDH that required evacuation and washout through a craniotomy. Intracranial infections can be a potentially devastating complication from MMA embolization in this patient population.

View Article and Find Full Text PDF

Aim: To present our experience on intracranial infections, and to determine the possible locations as well as the risk factors for surgical treatment.

Material And Methods: Over 13 years, 103 patients with intracranial infection underwent surgical evacuation. Seventy-one (68.

View Article and Find Full Text PDF