2 results match your criteria: "Epidemiology and Informatics at the University Medical Centre of the Johannes Gutenberg-University[Affiliation]"
Selection of patients with rectal cancer for neoadjuvant therapy using pre-therapeutic MRI - Results from OCUM trial.
Eur J Radiol
February 2022
Department of Surgery, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Purpose: No consensus is available on the appropriate criteria for neoadjuvant chemoradiotherapy selection of patients with rectal cancer. The purpose was to evaluate the accuracy of MRI staging and determine the risk of over- and undertreatment by comparing MRI findings and histopathology.
Method: In 609 patients of a multicenter study clinical T- and N categories, clinical stage and minimal distance between the tumor and mesorectal fascia (mrMRF) were determined using MRI and compared with the histopathological categories in resected specimen.
The Link Between Local Recurrence and Distant Metastases in Patients With Rectal Cancer.
Anticancer Res
June 2019
Institute of Medical Biostatistics, Epidemiology and Informatics at the University Medical Centre of the Johannes Gutenberg-University, Mainz, Germany
Background/aim: The relationships between local recurrence (LR), the development of distant metastases (DM) and prognosis in patients with rectal cancer remain unclear.
Patients And Methods: In 606 patients who underwent curative resection, the role of LR was assessed retrospectively by time-dependent multivariate Cox models with inverse probability of treatment weighting taking into account competing risks.
Results: Patients with LR had more DM than patients without LR (49/79, 62% vs.