306 results match your criteria: "Eosinophilic Pustular Folliculitis"

Article Synopsis
  • Eosinophilic pustular folliculitis (EPF) is a rare inflammatory skin disease mainly involving eosinophils and can appear in both follicle areas and less commonly in follicle-free areas.
  • This case study details two patients with difficult-to-treat EPF who had previous treatment failures with various standard therapies.
  • Both patients responded positively to the medication abrocitinib, achieving complete remission in one week and four weeks, with no side effects reported, suggesting it could be a safe treatment option for EPF.
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Eosinophilic Pustular Folliculitis in the Setting of Untreated Chronic Lymphocytic Leukemia.

Cutis

March 2024

University of Pittsburgh School of Medicine, Pennsylvania. Drs. Kim and Patton are from the Department of Dermatology, and Drs. Beatty and Choudhary are from the Department of Dermatopathology.

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Article Synopsis
  • The case study investigates the effectiveness and safety of a Janus kinase (JAK) inhibitor for treating generalized eosinophilic pustular folliculitis (EPF) in a 16-year-old patient who did not respond to traditional treatments.
  • The patient was initially treated with oral tofacitinib, resulting in significant symptom relief, but a relapse occurred when the dosage was reduced.
  • A switch to the more selective JAK1 inhibitor upadacitinib led to complete recovery, suggesting that JAK inhibitors could be a viable option for EPF patients resistant to standard therapies.
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A Case of Eosinophilic Pustular Folliculitis Misdiagnosed as Eczema.

Clin Cosmet Investig Dermatol

January 2024

Department of Cosmetic Dermatology, The Fifth People's Hospital of Hainan Province, Haikou, Hainan, People's Republic of China.

Article Synopsis
  • - Eosinophilic pustular folliculitis (EPF) is a rare skin condition, often misdiagnosed, where lesions appear primarily on the upper limbs, face, and trunk, but can initially show up on palms and soles.
  • - A male patient, misdiagnosed with eczema for ten years, experienced recurring skin issues and had a biopsy that confirmed EPF due to eosinophilic infiltrates in hair follicles.
  • - Treatment with 75mg/day of oral indomethacin led to complete resolution of his skin lesions, with no recurrence noted after three months.
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Article Synopsis
  • Infancy associated eosinophilic pustular folliculitis (I-EPF) is a variant of eosinophilic pustular folliculitis that occurs in children and shows distinct clinical and histological differences from classic EPF.
  • A study of two patients with I-EPF treated with topical indomethacin revealed unique patterns of eosinophilic infiltration compared to classic EPF, specifically less perifollicular and more perivascular infiltration.
  • Immunohistochemical analysis indicated that both I-EPF and classic EPF have CD4-dominant T cells, but classic EPF has significantly more CD68-positive cells; HPGDS-positive cells that promote eosinophil activity were also
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Clinical and Pathological Analysis of 10 Cases of Eosinophilic Pustular Folliculitis.

Clin Cosmet Investig Dermatol

September 2023

Department of Cosmetic Dermatology, The Fifth People's Hospital of Hainan Province, Haikou, Hainan, People's Republic of China.

Article Synopsis
  • - We analyzed data from 10 patients diagnosed with eosinophilic pustular folliculitis at a dermatology clinic between January 2020 and June 2023, noting that rashes appeared on various body parts and often evolved from scattered papules to larger, circular plaques.
  • - The conditions varied in severity, with most patients experiencing pustules and pruritus; the rashes affected different areas, including the face, trunk, hands, and feet.
  • - Histopathological examination revealed specific skin changes, and treatments using oral indomethacin, prednisone, and minocycline proved to be effective for managing the condition.
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Article Synopsis
  • - Eosinophilic pustular folliculitis (EPF) is a rare skin condition often diagnosed through invasive tissue examinations, which many patients avoid due to discomfort.
  • - Reflectance confocal microscopy (RCM) offers a non-invasive alternative that can accurately identify biopsy areas and provide objective imaging to track treatment progress.
  • - The article includes a case report showcasing how RCM effectively diagnosed and monitored treatment for EPF, highlighting its potential as a valuable diagnostic tool.
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Article Synopsis
  • * Histopathological examination of her lesions revealed various skin changes, including mild hyperkeratosis, pustules, and immune cell infiltration.
  • * Based on her symptoms and tissue analysis, the diagnosis was determined to be Wolf's isotopic response following her herpes zoster infection.
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Article Synopsis
  • - Eosinophilic pustular folliculitis (EPF) is a rare and chronic skin condition characterized by itchy, non-infectious pustules.
  • - The study reports a case of a 7-year-old child with infantile EPF (I-EPF) who was successfully treated with oral azithromycin and topical narrow band UVB light, resulting in no recurrence.
  • - This successful treatment approach may offer valuable insights for managing EPF in other pediatric patients.
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Article Synopsis
  • Eosinophilic pustular folliculitis (EPF) is a rare, chronic skin condition that is non-infectious and often linked to other health issues like HIV and syphilis.
  • A case study highlights the first known instance of EPF occurring in a patient with syphilis, suggesting a connection between the two conditions through similar immune responses.
  • The patient, a 48-year-old man, had symptoms that included redness and pustules on his face and neck, which improved significantly after treatment, though some skin pigmentation remained.
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Article Synopsis
  • - Hematologic-associated eosinophilic pustular folliculitis (EPF) is a skin condition seen in patients with blood cancers, often arising after treatments like chemotherapy or transplants.
  • - There are limited reports of this condition in children, highlighting its rarity in pediatric cases.
  • - A case study is presented where a skin smear stained with Wright's method helped quickly confirm the diagnosis of hematologic-associated EPF through the identification of eosinophils.
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Article Synopsis
  • Naltrexone, an effective medication for treating alcohol and opioid use disorders, is highlighted in this case report due to a patient experiencing a unique skin reaction after taking the drug.
  • The case involves a 20-year-old female with a history of several mental health and substance use disorders who faced drug-induced skin reactions twice within three months.
  • The report emphasizes the importance of a thorough medication history and monitoring for adverse effects when using naltrexone, aiming to prevent future reactions and ensure effective treatment for substance use disorders.
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Eosinophilic pustular folliculitis of infancy.

Arch Dis Child Fetal Neonatal Ed

July 2023

Department of Dermatology, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China.

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Article Synopsis
  • The text discusses a unique instance of eosinophilic pustular folliculitis arising as a side effect of mRNA COVID-19 vaccines.
  • The authors highlight the interesting histology findings from the biopsy of the affected skin.
  • This case emphasizes the potential skin reactions associated with the vaccines that might not be widely recognized.
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