Association between Complex and Gene Polymorphisms and Elite Endurance Sports in Koreans: A Case-Control Study.

and polymorphisms are associated with endurance exercise ability. This case-control study explored the association of and gene polymorphisms with elite pure endurance in Korean athletes, hypothesizing that individuals with both and genotypes would exhibit superior endurance. We recruited 934 elite athletes (713 males, 221 females) and selected 45 pure endurance athletes (36 males, 9 females) requiring "≥90% aerobic energy metabolism during sports events", in addition to 679 healthy non-athlete Koreans (361 males, 318 females) as controls.

Nationwide survey in Korea for risk assessment of pesticide residues in fishery and seaweed products.

Pesticide residues in fishery products are a concern due to environmental contamination. However, it is not sufficiently managed because of a lack of established standards. This study was conducted to monitor pesticide residues in fishery and seaweed product samples and assess the risk to humans.

Gasterophilus intestinalis infestation in lion (Panthera leo) and plains zebra (Equus quagga) in the Serengeti ecosystem: Morphological and molecular profiling.

This study was conducted to clarify the host specificity and the geographical distribution of Gasterophilus species (Diptera, Oestridae) in the Serengeti ecosystem. A total of 317 larvae were recovered from two common zebras (Equus quagga, formerly Equus burchellii) in Maswa Game Reserve, and 58 larvae were recovered from an African lion (Panthera leo) in the Serengeti National Park. The study emphasizes the rare occurrence of Gasterophilus sp.

Computed Tomographic Findings of Liver Cirrhosis in Dogs: Comparison between Compensated and Decompensated Cirrhosis.

This study aimed to describe computed tomography (CT) characteristics of histologically confirmed cirrhosis and to compare these CT characteristics between compensated and decompensated cirrhosis. Sixteen dogs who underwent contrast CT and histopathological examinations were included; eleven dogs were assigned to the compensated group, and five dogs were assigned to the decompensated group. Irregular hepatic contours with a diffuse nodular distribution and hepatic lymph node enlargement are common concomitant features of cirrhotic livers on CT images.

Heterologous immunization targeting the CST1 antigen confers better protection than ROP18 in mice.

To evaluate the protective efficacy induced by heterologous immunization with recombinant baculoviruses or virus-like particles targeting the CST1 and ROP18 antigens of .: Recombinant baculovirus and virus-like particle vaccines expressing CST1 or ROP18 antigens were developed to evaluate protective immunity in mice upon challenge infection with 450 (ME49). Immunization with CST1 or ROP18 vaccines induced similar levels of -specific IgG and IgA responses.

Development of a multi-channel visible bremsstrahlung measurement system for the effective charge in the versatile experiment spherical torus (VEST).

A diagnostic system for measuring the effective charge in the versatile experiment spherical torus (VEST) has been developed. The system utilizes a toroidal array to observe the plasma radius on the low magnetic field side, providing a spatially resolved Zeff. The target wavelength of visible bremsstrahlung (VB) was carefully selected to avoid contamination by line emissions.

Acellular Dermal Matrix without Basement Membrane in Immediate Prepectoral Breast Reconstruction: A Randomized Controlled Trial.

Background: Acellular dermal matrix (ADM) has become popular in various reconstructive procedures of different anatomic regions. There are different needs depending on the clinical application, including breast, abdominal wall, and any other soft-tissue reconstruction. Removal of the basement membrane, which consists of collagen fibers, may help achieve natural and soft breast reconstruction, which requires highly elastic ADMs.

A Multi-bit ECRAM-Based Analog Neuromorphic System with High-Precision Current Readout Achieving 97.3% Inference Accuracy.

This article proposes an analog neuromorphic system that enhances symmetry, linearity, and endurance by using a high-precision current readout circuit for multi-bit nonvolatile electro-chemical random-access memory (ECRAM). For on-chip training and inference, the system uses activation modules and matrix processing units to manage analog update/read paths and perform precise output sensing with feedback-based current scaling on the ECRAM array. The 250nm CMOS neuromorphic chip was tested with a 32 x 32 ECRAM synaptic array, achieving linear and symmetric updates and accurate read operations.

Elucidating Anomalous Intensity Ratios in Chlorine L-Edge X-ray Absorption Spectroscopy: Multiplet Effects and Core Rydberg Transitions.

A relativistic core-valence-separated equation-of-motion coupled cluster (CVS-EOM-CC) study of chlorine L-edge X-ray absorption near-edge structure (XANES) spectra using CHCl and CHICl as representative molecules is reported. The nearly identical intensity for the main features in the L- and L-edge XANES spectra is attributed to multiplet effects and the overlap between core-valence and core Rydberg transitions. The multiplet effects originating from the interaction between the core hole and the C-Cl σ* orbitals account for around half of the deviation of the L and L intensity ratio from the 2:1 ratio of the numbers of 2p and 2p electrons.

Development of Mesenchymal Stem Cell Encoded with Myogenic Gene for Treating Radiation-Induced Muscle Fibrosis.

Radiation therapy (RT) is a typical treatment for head and neck cancers. However, prolonged irradiation of the esophagus can cause esophageal fibrosis due to increased reactive oxygen species and proinflammatory cytokines. The objective of this study was to determine whether myogenic gene-transfected mesenchymal stem cells (MSCs) could ameliorate damage to esophageal muscles in a mouse model of radiation-induced esophageal fibrosis.

A DFT/MRCI Hamiltonian parameterized using only ab initio data. II. Core-excited states.

A newly parameterized combined density functional theory and multi-reference configuration interaction (DFT/MRCI) Hamiltonian, termed core-valence separation (CVS)-QE12, is defined for the computation of K-shell core-excitation and core-ionization energies. This CVS counterpart to the recently reported QE8 Hamiltonian [Costain et al., J.

"Straw in the Clay Soil" Strategy: Anticarbon Corrosive Fluorine-Decorated Graphene Nanoribbons@CNT Composite for Long-Term PEMFC.

Carbon corrosion poses a significant challenge in polymer electrolyte membrane fuel cells (PEMFCs), leading to reduced cell performance due to catalyst layer degradation and catalyst detachment from electrodes. A promising approach to address this issue involves incorporating an anticorrosive carbon material into the oxygen reduction reaction (ORR) electrode, even in small quantities (≈3 wt% in electrode). Herein, the successful synthesis of fluorine-doped graphene nanoribbons (F-GNR) incorporated with graphitic carbon nanotubes (F-GNR@CNT), demonstrating robust resistance to carbon corrosion is reported.

C-TERMINAL DOMAIN PHOSPHATASE-LIKE 1 promotes flowering with TAF15b by repressing the floral repressor gene FLOWERING LOCUS C.

Arabidopsis TATA-BINDING PROTEIN-ASSOCIATED FACTOR15b (TAF15b) is a plant-specific component of the transcription factor IID complex. TAF15b is involved in the autonomous pathway for flowering and represses the transcription of FLOWERING LOCUS C (FLC), a major floral repressor in Arabidopsis. While components of the autonomous flowering pathway have been extensively studied, scant attention has been directed toward elucidating the direct transcriptional regulators responsible for repressing FLC transcription.

Development of Ocular Muscle Stimulation Systems and Optimization of Electrical Stimulus Parameters for Paralytic Strabismus Treatment.

Paralysis of the extraocular muscles can lead to complications such as strabismus, diplopia, and loss of stereopsis. Current surgical treatments aim to mitigate these issues by resecting the paralyzed muscle or transposing the other recti muscles to the paralyzed muscle, but they do not fully improve the patient's quality of life. Electrical stimulation shows promise, while requiring further in vivo experiments and research on various stimulation parameters.

Equation-of-motion regularized orbital-optimized second-order perturbation theory with the density-fitting approximation.

The density-fitted equation-of-motion (EOM) orbital-optimized second-order perturbation theory (DF-EOM-OMP2) method is presented for the first time. In addition, κ-DF-EOM-MP2 and κ-DF-EOM-OMP2 methods are implemented with the addition of κ-regularization. The accuracy of the DF-EOM-OMP2, κ-DF-EOM-MP2, and κ-DF-EOM-OMP2 methods are compared to the density-fitted EOM-MP2 (DF-EOM-MP2), EOM coupled-cluster (CC) singles and doubles (DF-EOM-CCSD), and EOM-CCSD with the triples excitation correction model [EOM-CCSD(fT)] for excitation energies of many closed- and open-shell chemical systems.

In Vivo Optical Clearing of Mammalian Brain.

Established methods for imaging the living mammalian brain have, to date, taken optical properties of the tissue as fixed; we here demonstrate that it is possible to modify the optical properties of the brain itself to significantly enhance at-depth imaging while preserving native physiology. Using a small amount of any of several biocompatible materials to raise the refractive index of solutions superfusing the brain prior to imaging, we could increase several-fold the signals from the deepest cells normally visible and, under both one-photon and two-photon imaging, visualize cells previously too dim to see. The enhancement was observed for both anatomical and functional fluorescent reporters across a broad range of emission wavelengths.

Early Events in G-quadruplex Folding Captured by Time-Resolved Small-Angle X-Ray Scattering.

Time-resolved small-angle X-ray experiments (TR-SAXS) are reported here that capture and quantify a previously unknown rapid collapse of the unfolded oligonucleotide as an early step in G4 folding of hybrid 1 and hybrid 2 telomeric G-quadruplex structures. The rapid collapse, initiated by a pH jump, is characterized by an exponential decrease in the radius of gyration from 20.6 to 12.

Skin Improvement Effects of Ultrasound-Enzyme-Treated Collagen Peptide Extracts from Flatfish () Skin in an In Vitro Model.

Collagen is considered to be an intercellular adhesive that prevents tissue stretching or damage. It is widely utilized in cosmetic skin solutions, drug delivery, vitreous substitutions, 3D cell cultures, and surgery. In this study, we report the development of a green technology for manufacturing collagen peptides from flatfish skin using ultrasound and enzymatic treatment and a subsequent assessment on skin functionality.

Biologics for eosinophilic otitis media: a retrospective case study in a multidisciplinary center.

Purpose: Eosinophilic otitis media (EOM) is a difficult-to-treat otitis media characterized by eosinophilic accumulation in the middle ear mucosa and effusion. It is refractory to conventional treatments and is strongly associated with asthma and chronic rhinosinusitis with nasal polyps (CRSwNP). The diagnostic criteria for EOM were established by IINO in 2011.

Control ultrafiltration membrane fouling in Chlorella-laden water treatment by integrated heat-activated peroxydisulfate pre-oxidation and coagulation treatment.

The membrane fouling induced by algal extracellular organic matter (EOM) remain a bottleneck in restricting ultrafiltration (UF) application during harmful algal-water treatment. In current study, the application of heat-activated peroxydisulfate (PMS) and coagulation (Aluminum chlorohydrate, PACI) on membrane fouling behavior during Chlorella-laden water treatment was investigated. The membrane fouling mechanism was analyzed using the extended Derjaguin-Landau-Verwey-Over-beek (XDLVO) theory.