Anatomical variations of the external jugular veins and collaterals incidentally diagnosed with computed tomography in Shih Tzu dogs.

Introduction: The external jugular vein (EJV) is a superficial vein of the neck in dogs; its significance is evident in veterinary clinical practice, encompassing surgeries and interventional procedures. However, there have been no reports on EJV variations in canines, despite extensive studies on variations in the jugular veins in humans. This study aimed to use CT imaging to evaluate the prevalence of anatomic vascular variations of the EJVs in Shih Tzu dogs and to describe the clinical and CT characteristics of these vascular variants.

Stability and bifurcation analysis of a 2DOF dynamical system with piezoelectric device and feedback control.

This study aims to demonstrate the behaviors of a two degree-of-freedom (DOF) dynamical system consisting of attached mass to a nonlinear damped harmonic spring pendulum with a piezoelectric device. Such a system is influenced by a parametric excitation force on the direction of the spring's elongation and an operating moment at the supported point. A negative-velocity-feedback (NVF) controller is inserted into the main system to reduce the undesired vibrations that affect the system's efficiency, especially at the resonance state.

Creating ultra-strong and recyclable green plastics from marine-sourced alginate-chitosan nanowhisker nanocomposites for controlled release urea fertilizer.

In response to the pressing environmental challenge posed by petroleum-derived plastics, the development of green plastics derived from all-biomass nanocomposites offers promising solutions. However, conventional nanocomposites often prioritize enhanced stiffness at the expense of flexibility. We introduce sodium alginate (SA)/chitosan nanowhisker (CSW) nanocomposites, derived entirely from marine-sourced all-biomass, to create ultra-strong and flexible green plastics.

Sequential Fasciotomies for Managing Abdominal Compartment Syndrome: Porcine Experimental Study.

Introduction: Abdominal compartment syndrome (ACS) poses a significant clinical challenge, with high morbidity and mortality rates. Conventional treatment via decompressive laparotomy with open abdomen and temporary closure presents significant drawbacks. This experimental study evaluates the efficacy of open minimally invasive sequential fasciotomy in managing simulated ACS in a porcine model.

Fungal degradation of phenylacetate focusing on CRISPR/Cas9-assisted characterization of two oxidative enzyme genes of Akanthomyces muscarius AM1091.

The degradation of phenylacetate (PA) was investigated as a model to explore aromatic compound breakdown in the fungal system. Fungal strains capable of utilizing PA as their sole carbon source were isolated using a minimal solid medium supplemented with 0.5 % PA.

Reduced-dose Radiation Therapy for Stage IE Gastric Mucosa-Associated Lymphoid Tissue Lymphoma: A Multi-Institutional Prospective Study (KROG 16-18).

Purpose: Definitive radiation therapy (RT) of 30 Gy or higher is commonly recommended to treat Helicobacter pylori-independent gastric mucosa-associated lymphoid tissue (MALT) lymphoma with an excellent disease control rate. However, the efficacy of reduced-dose RT has not yet been evaluated in a prospective cohort study. This multi-institutional study aimed to determine the role of reduced-dose RT in the treatment of stage IE gastric MALT lymphoma.

CpG-adjuvanted virus-like particle vaccine induces protective immunity against Leishmania donovani infection.

Visceral leishmaniasis (VL) poses a significant public health challenge due to the lack of an approved human vaccine. We attempted to enhance the efficacy of virus-like particle vaccines expressing the Leishmania donovani promastigote surface antigen (LdPSA-VLP) by adjuvanting with CpG oligodeoxynucleotide (CpG-ODN). Here, adjuvanted vaccine-induced immune responses and their efficacies in mice challenged with mCherry-expressing L.

Diagrams in Polaritonic Coupled Cluster Theory.

We present a diagrammatic notation to derive the quantum-electrodynamic coupled cluster (QED-CC) equations needed for the description for polaritonic ground and excited states. Our presented notation is a generalization of the existing diagrammatic notation of standard electronic coupled-cluster theory. It is used to derive the QED-CC and QED-EOM-CC equations for the QED-CCSD-1-SD and QED-CCSD-12-SD truncation schemes.

The prevention and response to infectious diseases in long-term care facilities in Korea: a nationwide survey.

Objectives: Long-term care facilities (LTCFs) are communal environments for patients with chronic diseases or older adults, making them particularly susceptible to significant harm during infectious disease outbreaks. Nonetheless, LTCFs have historically been subject to less stringent infection prevention and control (IPC) mandates. This study aimed to assess the current state of LTCFs and to develop an IPC system tailored for these facilities following the coronavirus disease 2019 (COVID-19) pandemic.

Identification of a central network hub of key prognostic genes based on correlation between transcriptomics and survival in patients with metastatic solid tumors.

Background: Dysregulated pathways in cancer may be hub addicted. Identifying these dysregulated networks for targeting might lead to novel therapeutic options.

Objective: Considering the hypothesis that central hubs are associated with increased lethality, identifying key hub targets within central networks could lead to the development of novel drugs with improved efficacy in advanced metastatic solid tumors.

Toxicological and mechanistic insights into organic contaminants released from on-line membrane cleaning during ultrafiltration of algal-containing waters.

Eutrophication has significantly challenged the treatment of algae-contaminated water. Ultrafiltration has become an essential method for water purification, though frequent on-line chemical cleaning is necessary to maintain membrane permeability. This study aims to systematically investigate the impact of various chemical cleaning agents on the release of dissolved organic matters and toxic by-products, particularly from algal cells.

Efficacy of ursodeoxycholic acid for bile reflux after distal gastrectomy in patients with gastric cancer: a secondary analysis of the PEGASUS-D randomized clinical trial.

Background: Few studies have been conducted on the prevention of bile reflux in gastric cancer patients who have undergone gastrectomy. The aim of this study was to evaluate the efficacy and safety of ursodeoxycholic acid (UDCA) in preventing bile reflux after gastrectomy in patients with gastric cancer.

Methods: This study was a secondary analysis of the PEGASUS-D trial, a randomized, double-blind, placebo-controlled clinical trial.

Developing Porous Protein Cage Nanoparticles as Cargo-Loadable and Ligand-Displayable Modular Delivery Nanoplatforms.

Protein cage nanoparticles, self-assembled from protein subunits, provide distinct exterior and interior spaces and can carry diagnostic and/or therapeutic cargo agents through chemical conjugation, disassembly/reassembly process, or assembly-mediated encapsulation. Here, we developed porous SpyCatcher-mi3 (SC-mi3) as modular delivery nanoplatforms, capable of loading cargos through pores and displaying targeting ligands using SpyCatchers (SC) as anchors for SpyTagged (ST) ligands. Fluorescent dyes (F5M and A647) and a pH-sensitive prodrug (Aldox) were conjugated to the interior surface cysteines of SC-mi3, forming F5M@SC-mi3, A647@SC-mi3, and Aldox@SC-mi3.

Optical Gaps of Ionic Materials from GW/BSE-in-DFT and CC2-in-DFT.

This work presents a density functional theory (DFT)-based embedding technique for the calculation of optical gaps in ionic solids. The approach partitions the supercell of the ionic solid and embeds a small molecule-like cluster in a periodic environment using a cluster-in-periodic embedding method. The environment is treated with DFT, and its influence on the cluster is captured by a DFT-based embedding potential.

Comparison of computed tomography findings between perianal tumors originating from the anal sacs and perianal glands in dogs.

Tumors originating from the anal sacs and perianal glands are common tumors of the perianal region. However, differentiation of perianal tumors based on CT findings remains challenging because perianal tumors can show overlapping CT characteristics. Therefore, this retrospective, multi-institutional study aimed to identify the CT findings that can differentiate between tumors originating from the anal sacs and perianal glands in canines.

Orbital Involvement in Kimura's Disease Presenting as Diffuse Bilateral Extraocular Muscle Enlargement: A Case Report.

Kimura's disease (KD) is a rare, chronic inflammatory disorder characterized by angiolymphoid hyperplasia, peripheral eosinophilia, and elevated serum immunoglobulin E levels. It primarily affects young Asian males and typically involves the head and neck region, especially near the mandible and postauricular regions. Orbital involvement is unusual and extraocular muscle (EOM) involvement is exceedingly rare, with only a few cases reported in the literature.

Comparative analysis of single versus tandem autologous stem cell transplantation in patients with multiple myeloma in Korea: the KMM2102 study.

Tandem autologous stem cell transplantation can improve the prognosis of patients with multiple myeloma. However, the precise role of tandem transplantation remains debatable. We evaluated the clinical benefits of tandem transplantation retrospectively.

A spin-flip study of the diradical isomers of pyrrole, furan, and thiophene.

Heteroaromatic species are commonly found in complex gaseous mixtures, from tobacco smoke to petroleum and asphaltene combustion products. At high temperatures, C-H bond rupture produces various dehydro radical isomers. We have used the spin-flip formulation of equation-of-motion coupled cluster theory with single and double substitutions (EOM-SF-CCSD) to characterize the energies and wave functions of the lowest lying singlet and triplet states of the diradical (2,3), (2,4), (2,5), and (3,4) di-dehydro isomers of pyrrole, furan, and thiophene.

From the Beginning of the Korean Gynecologic Oncology Group to the Present and Next Steps.

The Korean Gynecologic Oncology Group (KGOG) was established in 2002 and is the only organization in Korea conducting multi-center clinical trials for gynecologic cancers. Since its re-establishment as a non-profit organization in 2021, KGOG has grown significantly, now including 207 gynecologic oncology specialists from 76 hospitals. This growth is a testament to the dedication and hard work of all those involved in the organization.

Anti-Melanogenic Effects of a Polysaccharide Isolated from Sporophyll Extracts.

is a temperate brown alga known to exert free radical-scavenging and anti-inflammatory effects. In this study, we investigated the skin-whitening effects of sporophyll extracts (UPEs) in α-melanocyte-stimulating hormone (α-MSH)-stimulated B16F10 melanoma cells. The crude polysaccharide fraction (UPF) was obtained via ethanol precipitation.

Assessment of the similarity-transformed equation of motion (STEOM) for open-shell organic and transition metal molecules.

This study benchmarks the newly re-implemented single-reference excited-state methods, IP-EOM-CCSD, EA-EOM-CCSD, and STEOM-CCSD, in ORCA6.0, with a focus on open-shell systems. We compare STEOM against EOM-CCSD, CC3, and CCSDT across a range of systems, including small organic radicals, hydrated transition metal (TM) ions, and TM diatomic systems with both closed and open-shell configurations.