Transurethral resection of the prostate (TUR-P) and associated risk of infective endocarditis.

Purpose: Bacteremia is a well-known complication to surgery and may result in infective endocarditis (IE). Transurethral resection of the prostate (TUR-P) may give rise to bacteremia, but the associated risk of IE is not well described. We aimed to examine risk of infective endocarditis following TUR-P.

Evaluation of elderly patients with bacteremia in the cardiology intensive care unit.

In this study, the blood culture results of patients aged >65 years who were admitted to the cardiology intensive care unit in a training and research hospital and who had positive blood cultures within the first 48 hours were evaluated. This was a retrospective, observational and nonrandomized study. Patient data at the time of the blood culture were included in the study.

Urinary Tract Infection in Children and the Potential Role of Pivmecillinam as a Treatment Option.

We investigated the potential role of pivmecillinam in the treatment of urinary tract infections in children. Among 351 children (0-6 years) with urinary tract infections, 83% could be treated with pivmecillinam following urine culture. Resistance was highest in infants (0-3 months) caused by the high prevalence of Enterococcus faecalis.

Antimicrobial resistance-attributable mortality: a patient-level analysis.

Background: The impact of antimicrobial resistance (AMR) on death at the patient level is challenging to estimate. We aimed to characterize AMR-attributable deaths in a large UK teaching hospital.

Methods: This retrospective study investigated all deceased patients in 2022.

Long-term Risk of Infection Among Patients Colonized With Antimicrobial-Resistant Pathogens: A Population-wide Cohort Study.

Background: Antimicrobial-resistant (AMR) pathogens represent an ongoing global health burden. Colonization is often a prerequisite for infection, but the risk of infection after AMR colonization is not well understood. Using population-level health administrative data, we sought to investigate the risk of infection with the same AMR organism after detection of colonization.

Diversity of Endodontic Enterococcus faecalis from Brazil with a High Occurrence of the ST 397 Clone.

Enterococcus faecalis is a common cause of nosocomial infections and is frequently associated with endodontic infections. However, there is a scarcity of studies addressing the genetic characterization of E. faecalis lineages most commonly associated with root canals.

resensitization of multidrug-resistant clinical isolates of and through phage-antibiotic synergy.

Bacteriophages are an increasingly attractive option for the treatment of antibiotic-resistant infections, but their efficacy is difficult to discern due to the confounding effects of antibiotics. Phages are generally delivered in conjunction with antibiotics, and thus, when patients improve, it is unclear whether the phages, antibiotics, or both are responsible. This question is particularly relevant for enterococcus infections, as limited data suggest phages might restore antibiotic efficacy against resistant strains.

The healthy human gut can take it all: vancomycin-variable, linezolid-resistant strains and specific bacteriocin-species interplay in spp.

spp. are opportunistic human pathogens colonizing the human gut and a significant reservoir for the continuous adaptation of hospital clones. However, studies on the features of enterococci species co-colonizing healthy individuals are scarce.

In vitro comparison of Enterococcus Faecalis survival in dentinal tubules following root canal therapy with AH plus, endoseal MTA, and cold ceramic sealers.

Background: Enterococcus faecalis (E. faecalis) is the most common microorganism responsible for post-endodontic infections, which can penetrate deep into dentinal tubules. This study aimed to compare the survival of E.

Unlocking the pharmacological potential of Brennnesselwurzel (Urtica dioica L.): an in-depth study on multifaceted biological activities.

Brennnesselwurzel (Urtica dioica L.) is recognized for its diverse pharmacological properties. With a range of chemical constituents, such as vitamins, minerals, phenolic compounds, fibers, and amino acids, Brennnesselwurzel (BWE) has a long history of traditional medicinal use in Europe and Asia.

Enterococcus avium Infection After Liver Transplantation in Vietnam: A Case Report.

Background: The infectious complications are the most common and can be life-threatening to liver transplant recipients, in particular, within the first month after transplantation. Early diagnosis of these severe complications and accurate detection of causative etiologies are crucial for the choice of therapeutic strategies and management of liver transplants.

Case Report: We present a case report of a patient with a history of primary sclerosing cholangitis who underwent a liver transplantation (LT) from a living donor.

necrotising fasciitis of the face after minor trauma presenting as periorbital cellulitis.

Necrotising fasciitis (NF), commonly referred to as 'flesh-eating disease', is a rare but life-threatening infection. It rapidly affects subcutaneous tissue, leading to necrosis of the overlying skin. Though primarily seen in the abdomen, perineum and lower limbs, periorbital involvement is rare.

Profile of co-occurring or secondary infections among COVID-19 patients with HBOT: a single-center retrospective study.

Introduction: This study was designed to describe the profile of co-occurring or secondary infections in hospitalized coronavirus disease 2019 (COVID-19) patients undergoing hyperbaric oxygen therapy (HBOT) and those without.

Methodology: Out of 716 COVID-19 patients, 79 cases of co-occurring or secondary infections were included. These patients were categorized into two groups based on their usage of HBOT.

Antimicrobial properties of copper tetraamine fluoride.

Background: A stable copper tetraamine fluoride (CTF) with low cytotoxicity has been developed for dental use.

Objective: To investigate the antimicrobial effects of CTF against common microbes associated with dental caries and periodontal disease.

Method: The minimum inhibitory concentrations (MIC) and minimum bactericidal/fungicidal concentrations (MBC/MFC) were used to evaluate the antimicrobial effects of CTF against eight common bacteria and one fungus associated with dental caries and periodontal disease.

The bacterial burden of worn face masks-observational research and literature review.

Introduction: Facemasks were widely mandated during the recent SARS-CoV-2 pandemic. Especially the use by the general population is associated with a higher risk of improper handling of the mask and contamination and potential adverse microbiological consequences.

Methods: We investigated and quantified bacterial accumulation in facemasks used by the general population, using 16S rRNA (Sanger Sequencing), culture and biochemical analysis along with Rose Bengal staining.

A Novel Approach to Identifying Appropriate Candidates for Transvenous Lead Extraction.

Background: The need for transvenous lead extractions (TLEs) in the setting of cardiac implantable electronic device-(CIED) related infections continues to rise. Delays in referral for TLE in this setting are common and are associated with increased mortality.

Objective: To describe the outcomes of a comprehensive approach, including an electronic medical record (EMR)-based notification algorithm designed to identify patients with active CIED-related infections to facilitate timely TLE.

Australian Group on Antimicrobial Resistance (AGAR) Australian Enterococcal Surveillance Outcome Program (AESOP) Bloodstream Infection Annual Report 2023.

From 1 January to 31 December 2023, fifty-six institutions across Australia participated in the Australian Enterococcal Surveillance Outcome Program (AESOP). The aim of AESOP 2023 was to determine the proportion of enterococcal bacteraemia isolates in Australia that were antimicrobial resistant, and to determine the molecular epidemiology. Of the 1,599 unique episodes of enterococcal bacteraemia investigated, 92.

Defining a panel of principal bacteria associated with endometritis.

The aim of this study is to present a panel that includes the main bacterial genera associated with endometritis. We conducted a search using the terms "endometritis women" OR "female endometritis" OR "pelvic inflammatory disease" AND bacteria* OR "uterine microbiome" in two databases: PubMed and Web of Science, without language or publication year restrictions. The panel is based on an analysis of 40 studies published over the past 38 years.

Antimicrobial coating of biologically synthesized silver nanoparticles on surgical fabric and surgical blade to prevent nosocomial infections.

In this study, biologically synthesized AgNPs were found to be effective against six hospital prevalent bacterial species (, , , Methicillin-resistant and ). AgNPs were deposited on the fabric and surgical blades using layer-by-layer and electrochemical deposition methods, respectively. The coated objects were characterized using scanning electron microscopy, X-ray diffraction and Fourier transform infrared spectroscopy and energy dispersive X-ray.

Analysis of the Chemical Composition, Antimicrobial, and Antioxidant Qualities of Microwave and Supercritical CO-Extracted Lavender Essential Oils Cultivated in a Hyperarid Region of Türkiye.

This study compares the chemical composition, antioxidant capacity, and antibacterial properties of lavender essential oils extracted using microwave-assisted extraction (MAE) and supercritical CO extraction (SCDE). Gas chromatography-mass spectrometry analysis revealed that the MAE oil contained higher levels of linalyl acetate (36.19%) and linalool (28.

New Conjugates of Vancomycin with Cell-Penetrating Peptides-Synthesis, Antimicrobial Activity, Cytotoxicity, and BBB Permeability Studies.

Vancomycin (Van) is a glycopeptide antibiotic commonly used as a last resort for treating life-threatening infections caused by multidrug-resistant bacterial strains, such as and spp. However, its effectiveness is currently limited due to the rapidly increasing number of drug-resistant clinical strains and its inherent cytotoxicity and poor penetration into cells and specific regions of the body, such as the brain. One of the most promising strategies to enhance its efficacy appears to be the covalent attachment of cell-penetrating peptides (CPPs) to the Van structure.

Disruption of the Enterococcus faecalis-Induced Biofilm on the Intraocular Lens Using Bacteriophages.

Purpose: To compare the effects of bacteriophages (phages) and vancomycin on Enterococcus faecalis-induced biofilms on the intraocular lens.

Methods: E. faecalis strains EF24, GU02, GU03, and phiEF14H1 were used.

Concomitant Therapy of Inactivated CECT7121 with Fluoroquinolones in a Enteritidis Murine Sepsis Model.

Optimization of existing antimicrobial therapies is a strategy proposed for extending antimicrobial activity and delaying resistance development. This study aimed to assess the effect of inactivated CECT7121 (I-EFCECT7121) in a combined therapy with Enrofloxacin or Ciprofloxacin in a Enteritidis murine sepsis model. Firstly, dose titration studies were performed to set up: (a) Enteritidis (SE) Lethal dose 99 (LD99) and (b) safety of I-EFCECT7121 (c) I-EFCECT7121 dosage scheme.

How do residential aged care antibiograms compare with other local resistance data?

Background: Antibiograms can optimise empirical antibiotic prescribing however they are not readily available for residential aged care facilities (RACFs) in Queensland, Australia. This study aimed to determine whether alternatively available data can be used to approximate resistance patterns for RACFs.

Method: Annual RACF-specific antibiograms were compared with local hospital antibiograms accessed through pathology providers.