Targeted Multimodality Treatment to Eliminate the Need for Enucleation in Advanced Coats Disease.

To examine the trends and outcomes in the management of Coats disease and evaluate the effects of a staged therapeutic approach using transpupillary laser vascular ablation, intravitreal (IVT) bevacizumab, and adjunct as-needed posterior sub-Tenon triamcinolone acetonide (used only in cases with a persistent active exudation) on globe retention, anatomic status, and visual acuity (VA). An evaluation was performed from 2005 to 2023. Previous case series published in the literature were reviewed.

Characteristics and Risks of Endophthalmitis Following 25-gauge Vitrectomy Surgery over a 14-year period.

Purpose: To analyze endophthalmitis characteristics and risks following a 25-gauge vitrectomy or microincision vitrectomy surgery (MIVS).

Design: Retrospective.

Subjects: Post-MIVS endophthalmitis patients.

The diagnosis and treatment progress of infectious endophthalmitis.

Endophthalmitis is a blinding disease that may lead to permanent vision loss. The diagnosis of endophthalmitis relies on clinical findings. It is crucial to identify causative microorganisms in time for subsequent treatment and saving vision.

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is an emerging pathogen that causes life-threatening infections in neonates and immunocompromised patients. In this study, we performed next-generation sequencing (NGS) to characterize 10 strains isolated from clinical patients in Nantong, China. Core, accessory, and unique genomes were composed of 2,891, 1,633, and 498 genes, respectively.

Evaluation of the reliability and readability of answers given by chatbots to frequently asked questions about endophthalmitis: A cross-sectional study on chatbots.

This study aimed to investigate the accuracy, reliability, and readability of A-Eye Consult, ChatGPT-4.0, Google Gemini and Copilot AI large language models (LLMs) in responding to patient questions about endophthalmitis. The LLMs' responses to 25 questions about endophthalmitis, frequently asked by patients, were evaluated by two ophthalmologists using a five-point Likert scale, with scores ranging from 1-5.

EFFICACY OF INTRACAMERAL MOXIFLOXACIN VERSUS TOPICAL MOXIFLOXACIN IN PREVENTING ACUTE ENDOPHTHALMITIS AFTER CATARACT SURGERY BY PHACOEMULSIFICATION.

Background: Endophthalmitis is an acute infection of anterior and posterior segment of the eye involving aqueous humour and vitreous cavity along with the other structures. It is classified into many types including bacterial, Fungal, protozoal, viral and atypical forms. Most common route of infection is exogenous either after the surgery or traumatic perforation Objectives were of evaluate the efficacy of intracameral moxifloxacin versus topical moxifloxacin in preventing postoperative acute endophthalmitis after cataract surgery by phacoemulsification.

Management of late postoperative capsular bag distension syndrome - two year case series.

Introduction: Late capsular bag distension syndrome (CBS) is a rare complication of the ^lcataract surgery.

Aim: The aim is to present 9 cases with delayed presentation and describe their successful management with surgical approach.

Method: A two-year retrospective review of 9 cases was undertaken.

Successful use of PRGF-endoret® and ILM peeling for full thickness macular hole in MacTel type 2: A case report and review of literature.

Purpose: To describe the successful use of plasma rich in growth factors (PRGF-Endoret®) and internal limiting membrane peeling for full thickness macular hole in Macular Telangiectasia type 2.

Case Presentation: A case report of a full thickness macular hole (FTMH) associated with Macular Telangiectasia (MacTel) type 2 is described. 25-G vitrectomy with internal limiting membrane (ILM) peeling and use of (PRGF-Endoret®) was performed.

A lacrimal drainage pathway disease-associated keratopathy (LDAK) case with non-infectious endophthalmitis.

Purpose: To report a case of lacrimal drainage pathway disease-associated keratopathy (LDAK) with endophthalmitis.

Observations: An 80-year-old man with diabetic retinopathy and nephropathy was referred to our hospital with endophthalmitis of the left eye. Slit-lamp examination revealed slight eye discharge, peripheral corneal ulcers, diffuse hyperemia of the conjunctiva, iris synechia, and a large amount of fibrin in the anterior chamber of the left eye.

Quality of Life in Patients With Acquired Anophthalmia Using an Ocular Prosthesis.

Purpose: To employ a validated survey for evaluation of quality of life (QoL) outcomes and associated factors in a US cohort of adult patients with acquired anophthalmia wearing a prosthesis.

Methods: A retrospective cohort study was performed at a single, US academic institution of patients cared for between 2012 and 2021. The electronic medical record database was queried for adult patients with a history of evisceration or enucleation surgery and placement of an orbital implant.

State-of-the-Art Review: Ocular Infections.

Collaborations between ophthalmologists and infectious disease specialists are critical for optimizing care of many patients with eye infections. We review challenges in common and uncommon eye infections to promote better understanding of these infections and prioritize areas for further research.

Endophthalmitis patients in Makassar City: molecular identification of pathogenic fungal profile.

Background: Endophthalmitis is a severe inflammation of the internal ocular structures, usually caused by bacterial or fungal infections, and can lead to rapid, irreversible blindness. Fungal endophthalmitis (FE), primarily due to Candida albicans and Aspergillus, is less common than bacterial endophthalmitis but has shown an increase in prevalence over the past two decades. Diagnosing FE is challenging and often delayed due to the time-consuming nature of traditional culture methods.

Pooled Multicenter Safety Analysis of Lupin's Intravitreal Biosimilar Ranibizumab (Ranieyes) in Chorioretinal Vascular Diseases.

Introduction: This study aims to evaluate the ocular and systemic safety profiles of intravitreal biosimilar ranibizumab Ranieyes (Lupin Pharmaceuticals, Mumbai, India) in real-world clinical settings across multiple chorioretinal vascular diseases, including neovascular age-related macular degeneration (nAMD), diabetic macular edema (DME), and retinal vein occlusion (RVO) in adults.

Methods: We conducted a retrospective, consecutive, interventional, uncontrolled multicenter study using data from three hospital networks in India. A total of 1401 eyes received 2194 injections of Ranieyes between June 2022 and November 2023.

Endophthalmitis Associated With Intravitreal Pegcetacoplan Injection.

To describe a case of endophthalmitis caused by , an encapsulated bacterium, after intravitreal (IVT) injection of pegcetacoplan. A single retrospective case was evaluated. An 88-year-old woman with a history of diabetes mellitus, on dialysis for chronic kidney disease, hypertension, hypothyroidism, diffuse large B-cell lymphoma, and geographic atrophy in both eyes received an IVT injection of pegcetacoplan in both eyes.

Povidone iodine-infused pars plana vitrectomy for severe fungal endophthalmitis.

Purpose: Arthrographis kalrae is an opportunistic fungus that can cause a severe and atypical endophthalmitis. In limited studies, low-dose povidone iodine has been shown to be effective in treating fulminant bacterial endophthalmitis. In this case report, we describe the successful treatment of recalcitrant keratitis-associated endophthalmitis with intraocular povidone iodine during pars plana vitrectomy.

Combined sewing machine technique cyclopexy With transscleral diode cyclophotocoagulation for complete posttraumatic cyclodialysis.

Purpose: To describe an alternative technique used in massive post-traumatic cyclodialysis. Classic techniques such as direct cyclopexy are performed ab externo and entail a higher risk of endophthalmitis or ciliary body hemorrhage. Therefore we present a case report using combined sewing machine technique cyclopexy with transscleral diode cyclophotocoagulation for complete post-traumatic cyclodialysis.

Bilateral Endogenous Endophthalmitis As a First Presentation of Endocarditis.

To present a case of bilateral endogenous endophthalmitis as the first presentation of endocarditis. A single case was evaluated. A 64-year-old Black woman presented with rapidly progressive bilateral vision loss.

Bilateral Anti-VEGF on Same-Day-Investigation on Safety in Retinopathy of Prematurity: A Multicenter Retrospective Study.

Purpose: To report an incidence of procedure-related complications in preterm infants with retinopathy of prematurity (ROP) treated with intravitreal anti-VEGFs injection in both eyes on the same day.

Design: Retrospective, multicenter case series.

Subjects: Preterm infants with ROP treated with anti-VEGF bilaterally on the same day.

Post-Cataract Surgery Fungal Endophthalmitis: 6-Year Experience in Management and Outcomes at a Tertiary Eye Care Center.

Purpose: This study aimed to describe the functional and anatomical outcomes of post-cataract surgery fungal endophthalmitis at King Khaled Eye Specialist Hospital (KKESH).

Patients And Methods: A retrospective analysis of clinical data from a single institution was performed. This study included 29 patients with post-cataract surgery endophthalmitis with suspected or confirmed fungal etiology who presented between January 1, 2017, and December 31, 2022.